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Trial Research Agreement • March 31st, 2017

CLINICAL TRIAL RESEARCH AGREEMENT No. 08/OVZ/16/064-P SMLOUVA O VÝZKUMNÉM KLINICKÉM HODNOCENÍ č.08/OVZ/16/064-P This Clinical Trial Research Agreement (“Agreement”) is entered into as of the date of signing by the last Party (“Effective Date”), by and among Fakultní nemocnice Ostrava, 17. listopadu 1790, 708 52 Ostrava, Czech Republic, Organization ID No.: 00843989, VAT Reg. No.: CZ00843989, person authorized to act and sign in respect of this Agreement: MUDr. Josef Srovnal, Deputy Director for Medical Care, Bank details: Česká národní banka, Na Příkopě 28, 115 03 Praha (Prague) 1, Account No.: 66332761/0710, IBAN: CZ59 0710 0000 0000 6633 2761,SWIFT: CNBACZPP, variable symbol for this study: 649071052 (“Institution”) and Prof. MUDr. Roman Hájek, CSc., with his place of work at Fakultní nemocnice Ostrava (University Hospital Ostrava), Klinika hematoonkologie (Clinic for Haematology and Oncology), 17. listopadu 1790, 708 52 Ostrava, Czech Republic (“Principal Investigator”)and Acerta Ph

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