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Study Agreement • February 16th, 2018

CLINICAL STUDY AGREEMENTconcluded pursuant to Section 269(2) of Act no. 513/1993,Commercial Code as amended(hereinafter only reffered as the “Agreement”) ZMLUVA O KLINICKOM SKÚŠANÍUzatvorená podľa § 269 ods. 2 zák,č. 513/1991 Zb. Obchodný zákonník, v znení neskorších predpisov (ďalej len “Zmluva”) This Agreement is concluded between: 1. AbbVie s.r.o.,Sponsor’s authorized representative based upon a power of attorney as of 3 January 2014: Karadžičova 10, 821 08 Bratislava, Slovak Republic, RN: 46640231, RN for tax: 2023529057, RN for VAT: SK2023529057, Statutory Body:Branislav Trutz, M.D., Managing Director; the Company is registered in Trade Register of District Court Bratislava I. Part Sro, insertion no. 81375/B, date of registration 11.05.2012 (hereinafter only reffered as"AbbVie")and 2.Univerzitná nemocnica L. Pasteura KošiceRegistered office: Rastislavova 43, 041 90 Košice, SlovakRepublic, RN : 00 606 707, RN for tax : 2021141969, RN for VAT: SK 2021141969Statutory Body: MUDr. Mila

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