EXHIBIT 1
JOINT FILING AGREEMENT
Each of the undersigned agrees that (i) the statement on Schedule 13D
relating to the Common Stock of Acura Pharmaceuticals, Inc., has been adopted
and filed on behalf of each of them, (ii) all future amendments to such
statement on Schedule 13D will, unless written notice to the contrary is
delivered as described below, be jointly filed on behalf of each of them, and
(iii) the provisions of Rule 13d-1(k)(1) under the Securities Exchange Act of
1934 apply to each of them. This agreement may be terminated with respect to the
obligations to jointly file future amendments to such statement on Schedule 13D
as to any of the undersigned upon such person giving written notice thereof to
each of the other persons signature hereto, at the principal office thereof.
This Agreement may be executed in any number of counterparts, each of
which shall be deemed an original, but all of which together shall constitute
one and the same instrument.
Date: December 7, 0000 XXXXX XXXXXXXXX HEALTH VENTURES FUND V, L.P.
By: Essex Woodlands Health Ventures Fund V,
L.L.C.
/s/ Xxxxxx X. Xxxxxx
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Name: Xxxxxx X. Xxxxxx
Title: Managing Director
ESSEX WOODLANDS HEALTH VENTURES FUND V, L.L.C.
/s/ Xxxxxx X. Xxxxxx
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Name: Xxxxxx X. Xxxxxx
Title: Managing Director
/s/ Xxxxx X. Xxxxxx
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Name: Xxxxx X. Xxxxxx
/s/ Xxxxxx X. Xxxxxx
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Name: Xxxxxx X. Xxxxxx
/s/ Xxxxxxxx Xxxxxxxxx
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Name: Xxxxxxxx Xxxxxxxxx
/s/ J. Xxxxxxx Xxxxxx
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Name: J. Xxxxxxx Xxxxxx