Forwarded
to ADC
9/27/96
between
Apollon, Inc.
(Apollon)
and
The Trustees of the University of Pennsylvania
(Penn)
TABLE OF CONTENTS
Recitals............................................................... 1
Article 1. Sponsored Research Work..................................... 1
Article 2. Period of Performance...................................... 2
Article 3. Reimbursement of Costs, Payment............................ 3
Article 4. Intellectual Property ..................................... 3
Article 5. Option to License.......................................... 5
Article 6. Confidentiality............................................ 6
Article 7. Publication, Use of Name................................... 7
Article 8. Termination................................................ 8
Article 9. Warranties and Indemnity................................... 8
Article 10. Additional Provisions..................................... 9
Attachment A........................................................... 14
This is made by and between The Trustees Of
The University of Pennsylvania, a Pennsylvania nonprofit corporation
("Penn"), located at Suite 000, 000 Xxxxx 00xx Xxxxxx, Xxxxxxxxxxxx, XX
00000-0000, and Apollon, Inc., a corporation organized and existing under the
laws of Pennsylvania ("Apollon"), having a place of business at Xxx Xxxxx
Xxxxxx Xxxxxxx, Xxxxxxx, XX 00000-0000.
This Agreement is effective as of the first day of July, 1996 ("Effective
Date").
Recitals
WHEREAS, Xxxxxxx and Penn desire to enter into a relationship involving
research by or under the direction of Xxxxxx Xxxxx, M.D., Ph.D. relating to
the development of therapeutic and/or diagnostic agents and modalities for
the treatment and prophylaxis of human cancer and tuberculosis, which act via
interactions with ribonucleotide reductase and/or enzyme involved in DNA
metabolism, and the development of genetic vaccines for tuberculosis.
WHEREAS, Xxxxxxx desires to support such research conducted by Penn in
accordance with the terms and conditions of this Agreement;
WHEREAS, the research program contemplated by this Agreement is of mutual
interest to Xxxxxxx and Penn and furthers the educational, scholarship and
research objectives of Penn as a nonprofit, tax-exempt educational
institution, and may derive benefits for both Apollon and Penn through
inventions, improvements, and/or discoveries;
NOW, THEREFORE, in consideration of the premises and of the promises and
mutual covenants contained herein, and intending to be legally bound hereby,
the parties hereto agree as follows:
Article 1. Sponsored Research Work
1.1 Sponsored Research means the research program described in
Attachment A to this Agreement.
1.2 Performance. Penn shall commence the performance of the Sponsored
Research promptly after the Effective Date of this Agreement and upon payment
by Xxxxxxx of any funds due at signing, and shall use reasonable efforts to
perform such Sponsored Research substantially in accordance with the terms
and conditions of this Agreement. Anything in this Agreement to the contrary
notwithstanding, Xxxxxxx and Penn may at any time amend or
extend the Sponsored Research by mutual written agreement, and incorporate
such as an attachment to this Agreement.
1.3 Conduct and Supervision of Sponsored Research. Xxxxxxx acknowledges
that Penn and the Principal Investigator shall have the freedom to conduct
and supervise the Sponsored Research in a manner consistent with Penn's
research mission.
1.4 Principal Investigator.
1.4.1 Xxxxxx Xxxxx, M.D., Ph.D. has agreed to serve as Principal
Investigator for the Sponsored Research and shall be responsible for the
administration and supervision of the Sponsored Research.
1.4.2 If the services of Xx. Xxxxx become unavailable to Penn for
any reason, Penn shall be entitled to designate another member of its faculty
who is acceptable to both parties to serve as the Principal Investigator of
the Sponsored Research. If a substitute Principal Investigator who is
acceptable to both parties has not been designated within sixty (60) days
after the original Principal Investigator ceases his services under this
Agreement, either party may terminate this Agreement upon written notice
thereof to the other party, subject to Article 8.
1.5 Reporting. Principal Investigator shall report to Xxxxxxx in
writing the status and results of Sponsored Research within thirty (30) days
after the end of each one (1) year term hereunder. Further, Principal
Investigator agrees to be available to Apollon personnel at times to mutually
agreed upon for the purpose of discussing the progress of the Sponsored
Research, and to make an oral presentation of the status and results of
Sponsored Research at Xxxxxxx's place of business at least once every six (6)
months. Reports hereunder shall be sent to:
Xxxxxx Xxxxx, Ph.D.
Associate Director, Business Development
Apollon, Inc.
Xxx Xxxxx Xxxxxx Xxxxxxx, Xxxxx 00
Xxxxxxx, XX 00000-1423
Article 2. Period of Performance
2.1 Term. The initial term of the Sponsored Research shall begin on
the Effective Date of this Agreement and shall end on June 30, 1998 unless
terminated sooner pursuant to Sections 1.4.2 or 8.1 hereof. This Agreement
may be extended or renewed only by written agreement of both parties and
incorporated as an attachment to this Agreement.
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Article 3. Reimbursement of Costs, Payment
3.1 Reimbursement of Costs. To support the Sponsored Research of this
Agreement, Xxxxxxx shall pay to Penn the amounts set forth in Attachment A
hereto for the initial term of the Sponsored Research. Funding amounts for
any renewal term shall be determined by the parties if and when the
determination to renew is made under Article 2 herein.
3.2 Payment. Xxxxxxx agrees to make quarterly payments in advance to
Penn in accordance with the payment schedule set forth in Attachment A, upon
receipt from Penn of a written request for each payment. All payments are to
be made by check (or electronic funds transfer) in U.S. dollars, payable to
"The Trustees of the University of Pennsylvania", and sent to the address set
forth in Article 10.5.
3.3 Financial Records and Reports. Penn shall maintain accurate
records and books of account in accordance with accepted university
accounting practices relating to this Agreement, and shall make such records
and books available to Apollon upon reasonable notice during Penn's normal
business hours, but not more frequently than once each calendar year.
3.4 Title to Equipment. Xxxxxxx agrees that title to any permanent
equipment, laboratory animals, or any other materials acquired with funds
provided under this Agreement shall vest in Penn upon acquisition, and such
equipment, animals, or materials shall remain the property of Penn following
completion or termination of the Sponsored Research.
Article 4. Intellectual Property
4.1.1 Penn Intellectual Property means and includes all technical
information, inventions, patent applications, patents, trade secrets,
developments, discoveries, biological materials, software, know-how, methods,
techniques, formulae, data, processes and other proprietary ideas, whether or
not patentable or copyrightable, that are first conceived, discovered,
developed or reduced to practice in the performance of the Sponsored Research
by the Principal Investigator or other inventors owning a duty to assign to
Penn during the performance of this Agreement.
4.2.1 Joint Intellectual Property means and includes all technical
information, inventions, patent applications, patents, trade secrets,
developments, discoveries, biological materials, software, know-how, methods,
techniques, formulae, data, processes and other proprietary ideas, whether or
not patentable or copyrightable, that are first conceived, discovered,
developed or reduced to practice in the performance of the Sponsored Research
jointly by the Principal Investigator or other inventors owing a duty to
assign to Penn by
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employees of Xxxxxxx or other inventors owing a duty to assign to Xxxxxxx
during the performance of this Agreement.
4.2 Prosecution of Patent Applications
and Maintenance of Patents
4.2.1 Xxxx agrees to provide promptly to Xxxxxxx a complete written
disclosure of any invention reasonably considered patentable disclosed by
Principal Investigator under this Agreement. Xxxxxxx agrees to advise Penn,
no later than 30 days after receipt of such disclosure, whether it requests
Penn to file and prosecute a patent application related to such invention.
If Xxxxxxx does not request Penn to file and prosecute a patent, Penn may
proceed with such preparation and prosecution at its own cost and expense.
4.2.2 Penn shall be responsible for and shall control the
preparation, filing, and prosecution of all patent applications and the
maintenance of all patents related to Penn Intellectual Property. Xxxxxxx
shall have full rights of consultation in this process. Penn and Xxxxxxx
shall be mutually responsible for and shall control preparation, filing, and
prosecution of all patent applications and the maintenance of all patents
related to Joint Intellectual Property. Penn and Xxxxxxx shall consult with
each other fully in this process. Xxxxxxx agrees to reimburse Penn for all
documented expenses (including legal fees, filing and maintenance fees or
other governmental charges) incurred in connection with the filing and
prosecution of the patent applications and maintenance of the patents that
Xxxxxxx has requested Penn to prosecute under this Section 4.2.
4.2.3 Apollon and Penn shall mutually determine the countries where
the patent applications will be filed and prosecuted, and where the patents
will be maintained. If Xxxxxxx declines to reimburse Penn for the filing,
prosecution and maintenance costs in any jurisdiction, Penn may pay such
costs, but such patents shall be excluded from Apollon's option under Article
5 hereof.
4.2.4 Each party agrees to cooperate with the other party to
execute all lawful papers and instruments and to make all rightful oaths and
declarations as may be necessary in the preparation and prosecution of all
patent applications and other applications referred to in this Article 4.
4.3 Prosecution of Trademarks and Copyrights. The preparation,
prosecution, and maintenance of copyright, trademark and other intellectual
property applications related to the Penn Intellectual Property and owned by
Penn shall be subject to the provisions of this Article 4, Section 4.2
regarding Prosecution of Patent Applications and Maintenance of Patents.
4.4 Penn Ownership. Penn shall retain all right, title and interest in
and to the Penn
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Intellectual Property and any patents, copyrights and other intellectual
property rights related thereto, regardless of which party prepares and
prosecutes the applications associated therewith, or maintains the patents,
copyrights or other intellectual property rights related to the Penn
Intellectual Property, subject to any express license granted to Apollon
under Section 5.1 hereof.
4.5 Apollon Ownership. Rights to inventions, improvements and/or
discoveries, whether or not patentable or copyrightable, and any patents,
copyrights and other intellectual property rights related thereto, relating
to Sponsored Research made solely by employees of Apollon using Apollon's
facilities shall belong to Xxxxxxx. Xxxxxxx agrees to disclose to Penn any
such inventions, improvements, and/or discoveries.
4.6 Joint Ownership. Rights to Joint Intellectual Property shall belong
jointly to Penn and to Apollon. Such inventions, improvements, and/or
discoveries shall be subject to the terms and conditions of this Agreement.
Article 5. Option to License
5.1 Option to License. In consideration of Xxxxxxx's funding of
the Sponsored Research and payment for intellectual property expenses as
provided for in Article 4, Penn grants Apollon an exclusive option to
negotiate a world-wide, exclusive, royalty-bearing license to practice Penn
Intellectual Property and to make, have made, use, sell and have sold
products using or incorporating Penn Intellectual Property. Xxxxxxx's option
must be exercised by written notice to Penn within six (6) months after Penn
discloses the Penn Intellectual Property to Apollon under Article 4, hereof
within nine (9) months from the Effective Date of this Agreement whichever is
later. If Apollon exercises its exclusive option, Penn will negotiate
exclusively with Apollon in good faith to determine the terms of a license
agreement as to each item of Penn Intellectual Property relating to the
development of therapeutic and/or diagnostic agents and modalities for the
treatment and prophylaxis of human cancer and tuberculosis, which act via
interactions with ribonucleotide reductase and/or enzyme involved in DNA
metabolism, and the development of genetic vaccines for tuberculosis under
this Agreement for which Apollon has exercised its exclusive option. If
Apollon fails to exercise its exclusive option within six (6) months after
disclosure of the Penn Intellectual Property to Apollon or within nine (9)
months from the Effective Date of this Agreement whichever is later, or if
Apollon and Penn fail to execute a license agreement within eighteen (18)
months from the Effective Date of this Agreement, Penn shall be free to
license the Penn Intellectual Property to any party upon such terms as Penn
deems appropriate, without any further obligation to Apollon. After a license
agreement is executed between Penn and Apollon, each new item of Penn
Intellectual Property for which Apollon exercises its exclusive option can be
added to such license agreement by an amendment.
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5.2 Retained Rights of U.S. Government. Any license granted to Apollon
pursuant to Section 5.1 hereof shall be subject, if applicable, to the rights
of the United States government reserved under Public Laws 96-517, 97-256 and
98-620, codified at 35 U.S.C. 200-212, and any regulations issued thereunder.
Penn hereby agrees that it has taken and will in the future take under such
laws to perfect its rights to the subject matter of any such license granted
to Xxxxxxx.
Article 6. Confidentiality
6.1 Confidential Information means (i) any information or material in
tangible form that is marked as confidential and proprietary by the
furnishing party at the time it is delivered to the receiving party, and (ii)
information that is furnished orally if the furnishing party identifies such
information as confidential or proprietary when it is disclosed and promptly
confirms such designation in writing within thirty (30) days after such
disclosure.
6.2 Confidentiality.
6.2.1 Xxxxxxx agrees to maintain in confidence and not to disclose
to any third party the Penn Intellectual Property and any Confidential
Information of Penn received pursuant to this Agreement, without the prior
written consent of Penn. The foregoing obligation shall not apply to:
6.2.1.1 information that is known to Xxxxxxx or
independently developed by Apollon prior to the time of disclosure, in each
case, to the extent evidenced by written records promptly disclosed to Penn
upon receipt to the Confidential Information;
6.2.1.2 information disclosed to Apollon by a third party
that has a right to make such disclosure;
6.2.1.3 information that becomes patented, published or
otherwise part of the public domain as a result of acts of Penn or a third
person obtaining such information as a matter of right;
6.2.1.4 information that is required to be disclosed by
order or regulation of the U.S. Food and Drug Administration or similar
authority or a court of competent jurisdiction; provided that the parties
shall use their best efforts to obtain confidential treatment of such
information by the agency or court; or
6.2.1.5 information disclosed by Xxxxxxx to a third party
under an agreement of confidentiality in furtherance of the development of
the Penn Intellectual Property.
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6.3 Xxxxxxx agrees to take all reasonable steps to protect the
Confidential Information of Penn with the same degree of care the Apollon
uses to protect its own Confidential or Proprietary Information. Without
limiting the foregoing, Xxxxxxx agrees to ensure that all of its employees
having access to the Confidential Information of Penn are on need-to-know
basis and are obligated (in writing) to abide by Xxxxxxx's obligations
hereunder.
6.4 Penn shall not be obligated to accept any Confidential Information
from Apollon. If Xxxxxxx desires to furnish any Confidential Information to
the Principal Investigator or other Penn personnel, Xxxxxxx may request such
individual to sign a confidentiality agreement with Xxxxxxx. Penn bears no
institutional responsibility for maintaining the confidentiality of any
Confidential Information of Apollon.
Article 7. Publication, Use of Name
7.1 Apollon acknowledges that the basic objective of research activities
at Penn is the generation of new knowledge and its expeditious dissemination.
To further that objective, Penn retains the right, at its discretion, to
demonstrate, publish or publicize the results of the Sponsored Research,
subject to the provisions of Section 7.2 below.
7.2 Should Principal Investigator desire to disclose publicly, in
writing or by oral presentation, the results of the Sponsored Research,
Principal Investigator shall notify Xxxxxxx and Penn in writing of his
intention at least thirty (30) days before such disclosure. The Principal
Investigator shall include with such notice a description of the oral
presentation or, in the case of a manuscript or other proposed written
disclosure, a current draft of such written disclosure. Xxxxxxx may request
Penn, no later than thirty (30) days following the receipt of such notice, to
file a patent, copyright or other application related to such invention. All
such filings shall be subject to the provisions of Article 4 of this
Agreement. Upon receipt of such request, Penn shall arrange for and
Principal Investigator agrees to a short delay in publication, not to exceed
sixty (60) days, to permit filing of a patent application, copyright or other
application by Penn or Apollon as provided by Section 4.2 hereof, or if Penn
declines to file such application, to permit Xxxxxxx to make such a filing.
7.3 Use of Name. Penn agrees not to use directly or indirectly Xxxxxxx's
name without Xxxxxxx's prior written consent except that Penn may acknowledge
Xxxxxxx's funding of this Sponsored Research in scientific publications and
in listings of Sponsored Research projects. Xxxxxxx agrees not to use
directly or indirectly Penn's name, or the name of any trustee, officer,
faculty member, student or employee thereof, without Penn's prior written
consent which shall not be unreasonably withheld. Notwithstanding the
foregoing, Apollon and Penn may include an accurate description of the terms
of this Agreement to the extent required under federal or state securities or
other disclosure laws and internal communications.
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Article 8. Termination
8.1 Termination
8.1.1 In addition to the termination right set forth in Section
1.4.2 hereof, either party may terminate this Agreement effective upon
written notice to the other party, if the other party breaches the terms of
this Agreement and fails to cure such breach within sixty (60) days after
receiving notice thereof.
8.1.2 This Agreement shall automatically terminate if Xxxxxxx
becomes insolvent; or if voluntary or involuntary proceedings by or against
Apollon are instituted in bankruptcy or under any insolvency law; or if a
receiver or custodian is appointed for Apollon; or if proceedings, if
involuntary, shall not have been dismissed within sixty (60) days after the
date of filing; or if Xxxxxxx makes an assignment for the benefit of
creditors; or if substantially all of the assets of Apollon are seized or
attached and not released within sixty (60) days thereafter.
8.1.3 In addition, Xxxxxxx may terminate this Agreement for any
reason upon ninety (90) days prior written notice to Penn.
8.2 Effect of Termination. In the event of termination of this Agreement
prior to its stated term whether for breach or for any other reason
whatsoever, Penn shall be entitled to retain from the payments made by
Apollon prior to termination Penn's reasonable costs of concluding the work
in progress. Allowable costs include, without limitation, all costs or
noncancellable commitments incurred prior to the receipt, or issuance, by
Penn of the notice of termination, and the full cost of each student and
faculty member supported hereunder through the end of such commitments. In
the event of termination, Penn shall submit a final report of all costs
incurred and all funds received under this Agreement within sixty (60) days
after the effective termination date. The report shall be accompanied by a
check in the amount of any excess of funds advanced over costs and allowable
commitments incurred. In case of a deficit of funds, Xxxxxxx agrees to pay
Penn the amount needed to cover costs and allowable commitments incurred by
Penn under this Agreement.
8.3 Survival. Termination of this Agreement shall not affect the rights
and obligations of the parties accrued prior to termination hereof. The
provisions of Articles 4, 6, 9, and 10 shall survive such termination.
Article 9. Warranties and Indemnity
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9.1 No Warranties. PENN MAKES NO WARRANTIES, EXPRESS OR IMPLIED, AS TO
ANY MATTER WHATSOEVER, INCLUDING, WITHOUT LIMITATION, WARRANTIES WITH RESPECT
TO THE CONDUCT, COMPLETION, SUCCESS OR PARTICULAR RESULTS OF THE SPONSORED
RESEARCH, OR THE CONDITION OF ANY INVENTION(S) OR PRODUCTS(S), WHETHER
TANGIBLE OR INTANGIBLE, CONCEIVED, DISCOVERED, OR DEVELOPED UNDER THIS
AGREEMENT, OR THE MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE OF THE
SPONSORED RESEARCH OR ANY SUCH INVENTION OR PRODUCT. PENN SHALL NOT BE
LIABLE FOR ANY DIRECT, CONSEQUENTIAL, PUNITIVE OR OTHER DAMAGES SUFFERED BY
XXXXXXX OR ANY OTHER PERSON RESULTING FROM THE SPONSORED RESEARCH OR THE USE
OF ANY SUCH INVENTION OR PRODUCT.
9.2 Indemnity.
9.2.1 Xxxxxxx agrees to defend, indemnify and hold harmless Penn,
the Principal Investigator and any of Penn's faculty, students, employees,
trustees, officers, affiliates and agents (hereinafter referred to
collectively as the "Indemnified Persons") from and against any and all
liability, claims, lawsuits, losses, damages, costs or expenses (including
attorneys' fees), which the Indemnified Persons may hereafter incur, suffer
or be required to pay by reason of: (a) Xxxxxxx's use of the results of
Sponsored Research; (b) any breach of this Agreement by Xxxxxxx; or (c) any
wrongful or negligent act or omission of Apollon, its employees, affiliates,
contractors, licensees or agents relating to any of the foregoing. Penn
shall notify Apollon upon learning of the institution or threatened
institution of any such liability, claims, lawsuits, losses, damages, costs
and expenses and Penn shall cooperate with Xxxxxxx in every proper way in the
defense or settlement thereof at Apollon's request and expense. Xxxxxxx's
indemnification hereunder shall not apply to any liability, claim, damage,
loss, cost or expense to the extent it is attributable to the negligence, or
reckless or intentional misconduct of any Indemnified Person hereunder.
9.2.2 Each party hereby assumes any and all risks of personal injury
and property damage attributable to the negligent acts or omissions of their
respective officers, employees, and agents hereof.
Article 10. Additional Provisions
10.1 Arbitration.
10.1.1 All disputes which cannot be resolved arising between Penn
and Apollon under this Agreement shall be settled by arbitration conducted in
the English language in accordance with the Commercial Arbitration Rules of
the American Arbitration Association.
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The parties will cooperate with each other in causing the arbitration to be
held in as efficient and expeditious a manner as practicable. Any
arbitration proceeding instituted under this Agreement shall be brought in
Philadelphia, Pennsylvania.
10.1.2 Any award rendered by the arbitrators shall be final and
binding upon the parties hereto. Judgment upon the award may be entered in
any court of record of competent jurisdiction. Each party shall pay its own
expenses of arbitration and the expenses of the arbitrator(s) shall be
equally shared unless the arbitrator(s) assess as part of their award all or
any part of the arbitration expenses of one party (including reasonable
attorneys' fees) against the other party.
10.1.3 Apollon irrevocably and unconditionally consents to the
jurisdiction of any such proceeding and waives any objection that it may have
to personal jurisdiction or the laying of venue of any such proceeding.
10.2 Assignment. No rights hereunder may be assigned by Xxxxxxx,
directly or by merger or other operation of law, without the express written
consent of Penn, which shall not be unreasonably withheld; provided, however,
that such consent shall not be required in the event or transfer by Xxxxxxx
of all or substantially all of the business to which it pertains. Any
prohibited assignment of this Agreement on the rights hereunder shall be null
and void. No assignment shall relieve Xxxxxxx of responsibility for the
performance of any accrued obligations which it has prior to such assignment.
This Agreement shall inure to the benefit of permitted assigns of Apollon.
10.3 No Waiver. A waiver by either party of a breach or violation of
any provision of this Agreement will not constitute or be construed as a
waiver of any subsequent breach or violation of that provision or as a waiver
of any breach or violation any other provision of this Agreement.
10.4 Independent Contractor. Nothing herein shall be deemed to
establish a relationship of principal and agent between Penn and Xxxxxxx, nor
any of their agents or employees for any purpose whatsoever. This Agreement
shall not be construed as constituting Penn and Apollon as partners, or as
creating any other form of legal association or arrangement which would
impose liability upon one party for the act or failure to act of the other
party.
10.5 Notices. Any notice under this Agreement shall be sufficiently
given if sent in writing by prepaid first class, certified or registered
mail, return receipt requested, addressed as follows:
If to Penn:
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Office of Research Administration
Philadelphia, PA 19104-3246
Attn: Executive Director
Office of General Counsel
000 Xxxxxxx Xxxx
Xxxxxxxxxx xx Xxxxxxxxxxxx
Xxxxxxxxxxxx, XX 00000-6303
Attn: General Counsel
cc: Dr. Xxxxxx Xxxxx
University of Pennsylvania
School of Medicine
Infectious Diseases
000 Xxxxxxx Xxxxxxxx
Xxxxxxxxxxxx, XX 00000-6073
If to Apollon:
Xx. Xxxxxxx X. Xxxxxxxx, Xx.
President and CEO
Apollon, Inc.
One Great Valley Parkway
Malvern, PA 19355-1423
10.6 Entire Agreement; Changes. This Agreement embodies the entire
understanding between the parties relating to the subject matter hereof and
supersedes all prior understandings and agreements, whether written or oral.
This Agreement may not be varied except by a written document signed by duly
authorized representatives of both parties.
10.7 Severability. Any of the provisions of this Agreement which are
determined to be invalid or unenforceable in any jurisdiction shall be
ineffective to the extent of such invalidity or unenforceability in such
jurisdiction, without rendering invalid or unenforceable the remaining
provisions hereof or affecting the validity or unenforceability of any of the
terms of this Agreement in any other jurisdiction.
10.8 Headings. The headings and captions used in this Agreement are for
convenience of reference only and shall not affect its construction or
interpretation.
10.9 No Third Party Benefits. Nothing in this Agreement, express or
implied, is intended to confer on any person other than the parties hereto or
their permitted assigns, any benefits, rights or remedies.
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10.10 Governing Law. This Agreement shall be construed and governed in
accordance with the laws of the Commonwealth of Pennsylvania, without giving
effect to conflict of law provisions.
10.11 Counterparts. This Agreement shall become binding when any one or
more counterparts hereof, individually or taken together, shall bear the
signatures of Penn and Xxxxxxx. This Agreement may be executed in any number
of counterparts, each of which shall be deemed an original as against the
party whose signature appears thereon, but all of which taken together shall
constitute but one and the same instrument.
10.12 Independent Research. This Agreement shall not be construed to
limit the freedom of individuals participating in the Sponsored Research to
engage in any other research. However, during the term of this Agreement,
the Principal Investigator shall not knowingly enter into any agreement with
non-governmental third parties on the same subject matter covered by this
Agreement.
10.13 Nondiscrimination. In accordance with U.S. laws, Penn and Xxxxxxx
shall not discriminate against any employee or applicant for employment
because of race, color, sex, sexual or affectional preference, age, religion,
national or ethnic origin, or handicap.
10.14 Force Majeure. Neither party shall be liable for any failure to
perform as required by this Agreement to the extent such failure to perform
is due to circumstances reasonably beyond such party's control, including,
without limitation, labor disturbances or labor disputes of any kind,
accidents, failure of any governmental approval required for full
performance, civil disorders or commotions, acts of aggression, acts of God,
energy or other conservation measures imposed by law or regulation,
explosions, failure of utilities, mechanical breakdowns, material shortages,
disease, or other such occurrences.
10.15 Export Control. This is subject to
United States laws and regulations controlling the export of technical data,
computer software, laboratory prototypes, and all other export controlled
commodities. These laws include, but are not limited to, the Arms Export
Control Act and the Export Administration Act as they may be amended. All
rights granted to Apollon by this are contingent
upon compliance with these laws and regulations. Apollon shall not, directly
or indirectly, export any export controlled commodities, which are subject to
this , unless the required authorization and/or
license is obtained from the proper government agency(ies) prior to export.
By granting rights in this , Penn does not
represent that export authorization or an export license will not be
necessary or, if necessary, that such authorization or export license will be
granted.
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IN WITNESS WHEREOF, the duly authorized representatives of the parties
hereby execute this as of the date first written
above.
THE TRUSTEES OF THE
UNIVERSITY OF PENNSYLVANIA APOLLON, INC.
By: /s/ Xxxxx X. Xxxxxxxx By: /s/ Xxxxxxx X. Xxxxxxxx
--------------------------- ------------------------------
Name: /s/ Xxxxx X. Xxxxxxxx Name: /s/ Xxxxxxx X. Xxxxxxxx, Xx.
------------------------- ----------------------------
Title: Research Administration Title: President and CEO
------------------------ ----------------------------
Date: 8/28/96 Date: 10 Sep. 96
------------------------ ----------------------------
Acknowledged and agreed to be
Principal Investigator:
By: /s/ Xxxxxx Xxxxx
--------------------------
Xxxxxx Xxxxx, M.D., Ph.D.
Date: Aug. 27 1996
-------------------------
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Attachment A
Summary of Sponsored Research
Work Scope
1) Research by or under the direction of Dr. Xxxxxx Xxxxx relating to
the development of therapeutic and/or diagnostic agents and modalities for
the treatment and prophylaxis of human cancer and tuberculosis, which act via
interactions with ribonucleotide reductase and/or enzyme involved in DNA
metabolism, and the development of genetic vaccines for tuberculosis.
2) Details of Program - See Attachment B
Principal Investigator
Xxxxxx Xxxxx, M.D., Ph.D.
Representative of Apollon
1) Name: Xxxxxxx X. Xxxxxxxx, Xx., Ph.D.
2) Phone Number: 000-000-0000
Period of Performance
1 February 1996 to 31 January 1998
Report Schedule
Final report within thirty (30) days after termination
Budget
$260,000.00 total costs over two years
Invoice and Payment Schedule
Year 1 $ Year 2 $
--------------------- -------------
February 1 1996 $ 32,500.00 1997 $ 32,500.00
May 1 1996 $ 32,500.00 1997 $ 32,500.00
August 1 1996 $ 32,500.00 1997 $ 32,500.00
November 1 1996 $ 32,500.00 1997 $ 32,500.00
----------- -----------
Totals $130,000.00 $130,000.00
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