HYBRIDON, INC. AND SUBSIDIARIES (A DEVELOPMENT STAGE COMPANY)

  


                     5

          HYBRIDON, INC. AND SUBSIDIARIES
          (A DEVELOPMENT STAGE COMPANY)


       
                             
                   6-MOS
                                    DEC-31-1998
                                       JAN-01-1998
                                         JUN-30-1998
                                                 5,518,682
                                                   0
                                            264,122
                                                   0
                                                    0
                                      12,116,480
                                                25,702,326
                                        13,199,366
                                        28,106,665
                                 13,706,877
                                                1,896,431
                                                  15,255
                                          0
                                                6,248
                                           (12,481,854)
                          28,106,665 
                                                1,506,689 
                                       2,369,051 
                                                          0
                                         15,693,700
                                               0
                                               0
                                     2,583,963
                                     (15,908,612)
                                                   0
                                 (15,908,612)
                                                 0
                                        8,876,685
                                                      0
                                         (7,031,927)
                                              (.86)
                                              (.86)