AMENDMENT TO JANUS ASPEN SERIES INVESTMENT ADVISORY AGREEMENT MODERATE ALLOCATION PORTFOLIO

Exhibit (d)(75)

AMENDMENT TO

JANUS ASPEN SERIES

INVESTMENT ADVISORY AGREEMENT

MODERATE ALLOCATION PORTFOLIO

     THIS AMENDMENT is made this 1^st day of May, 2013, between JANUS ASPEN SERIES, a Delaware statutory trust (the “Trust”), and JANUS CAPITAL MANAGEMENT LLC, a Delaware limited liability company (“JCM”).

W I T N E S S E T H

     WHEREAS, the Trust and JCM are parties to an Investment Advisory Agreement on behalf of Dynamic Allocation Portfolio (the “Fund”), dated May 1, 2009, amended July 1, 2010 and August 31, 2011 (the “Agreement”);

     WHEREAS, the parties desire to amend the Agreement as set forth in greater detail below;

     WHEREAS, the name of Moderate Allocation Portfolio has been changed to Global Allocation Portfolio — Moderate;

     WHEREAS, pursuant to Section 11 of the Agreement, any amendment to the Agreement is subject to approval (i) by a majority of the Trustees, including a majority of the Trustees who are not interested persons (as that phrase is defined in Section 2(a)(19) of the Investment Company Act of 1940, as amended (the “1940 Act”)) of any party to the Agreement, and (ii) if required by applicable law, by the affirmative vote of a majority of the outstanding voting securities of the Fund (as that phrase is defined in Section 2(a)(42) of the 1940 Act);

     WHEREAS, the parties have obtained Trustee approval as set forth above, and the parties agree that a shareholder vote is not required to amend the Agreement; and

     NOW, THEREFORE, in consideration of the premises and of the mutual agreements set forth below, the parties agree to amend the Agreement as follows:

     1. All references to “Moderate Allocation Portfolio” have been changed to “Global Allocation Portfolio — Moderate.”

     2. The parties acknowledge that the Agreement, as amended, remains in full force and effect as of the date of this Amendment, and that this Amendment, together with the Agreement and any prior amendments, contains the entire understanding and the full and

complete agreement of the parties and supercedes and replaces any prior understandings and agreements among the parties respecting the subject matter hereof.

     3. This Amendment may be contemporaneously executed in two or more counterparts, each of which shall be deemed an original but all of which together shall constitute one and the same instrument.

     IN WITNESS WHEREOF, the parties have caused their duly authorized officers to execute this Amendment as of the date first above written.

	JANUS CAPITAL MANAGEMENT LLC
	By:	/s/ Xxxxx X. Xxxxxx
		Xxxxx X. Xxxxxx
		Senior Vice President and General Counsel
	JANUS ASPEN SERIES
	By:	/s/ Xxxxxxxxx Xxxxxxxxxx-Xxxxxx
		Xxxxxxxxx Xxxxxxxxxx-Xxxxxx
		Chief Legal Counsel, Vice President and Secretary