September 5, 2007 Meda AB Box 906 Pipers vag 2A Solna, Sweden Attention: Anders Lonners, CEO Dear Anders:

Exhibit 10.30

September 5, 2007

Meda AB

Box 906

Pipers vag 2A

17009

Solna, Sweden

Attention: Xxxxxx Xxxxxxx, CEO

Dear Xxxxxx:

This letter will confirm our agreement with Meda that neither BDSI, Arius nor Arius Two will take any action to amend, modify or terminate any agreement with a third party which would cause a termination or modification of Meda’s rights under the License and Development Agreement dated as of the date hereof, and each document, instrument, agreement, license and/or sublicense related thereto, unless provision is made for Meda’s rights under such License and Development Agreement and such related documents to continue undisturbed.

Very Truly Yours,
BioDelivery Sciences International, Inc.
By:		/s/ Xxxx X. Xxxxx, President and CEO
Arius Pharmaceuticals, Inc.
By:		/s/ Xxxx X. Xxxxx, President and CEO
Arius Two, Inc.
By:		/s/ Xxxx X. Xxxxx, President and CEO