1 EXHIBIT 4.3 TRANSCEND THERAPEUTICS, INC. Amendment No. 1 of Second Amended and Restated Registration Rights Agreement ----------------------------- This Amendment No. 1 (the "Amendment") to the Second Amended and Restated Registration Rights...
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EXHIBIT 4.3
TRANSCEND THERAPEUTICS, INC.
Amendment No. 1 of Second Amended and Restated
Registration Rights Agreement
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This Amendment No. 1 (the "Amendment") to the Second Amended and Restated
Registration Rights Agreement dated as of August 21, 1996 among Transcend
Therapeutics, Inc., a Delaware corporation and the Holders, as defined therein
(the "Agreement") is made as of this 3rd day of March 1997. All capitalized
terms used herein and not otherwise defined herein shall have the meanings
described to them in the Agreement.
WHEREAS, in connection with the Company's February 1997 $1,039,000 bridge
financing, the Company intends to issue warrants (the "1997 Warrants") to
purchase shares of its Common Stock, par value $.01 per share, to the holders of
the Company's Non-Convertible Preferred Stock (the "1997 Warrantholders"); and
WHEREAS, the parties wish to provide registration rights with respect to
the shares of Common Stock issuable upon exercise of the 1997 Warrants.
NOW, THEREFORE, for valuable consideration, it is agreed as follows:
i. The definition of "Common Stockholder" in the Agreement is
hereby amended to renumber (iii) as (iv) and to insert therein
the following:
"(iii) the 1997 Warrantholders or any persons or entities to
whom the rights granted under this Agreement are transferred
by any such 1997 Warrantholder, and"
ii. The Agreement is hereby amended to include within the
definition of the term "Common Registrable Shares" the shares of
Common Stock issued or issuable upon exercise of the 1997
Warrants issued and sold to the 1997 Warrantholders pursuant to
the Non-Convertible Preferred Stock and Warrant Purchase
Agreement of even date herewith by and among the Company and the
1997 Warrantholders.
iii. Each of the 1997 Warrantholders hereby agrees to become a
party to, and to be bound by the Agreement.
iv. Each of the 1997 Warrantholders shall have all of the rights
provided to Purchasers under the Agreement.
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v. Section 16.1 of the Agreement is hereby amended to include
the following information regarding Notices to Purchasers:
If to ▇▇▇▇▇▇ ▇▇▇▇▇, M.D. at:
▇▇▇▇▇▇ ▇▇▇▇▇, M.D.
c/o Transcend Therapeutics, Inc.
▇▇▇ ▇▇▇▇▇▇▇▇ ▇▇▇▇▇
▇▇▇ ▇▇▇▇▇ ▇▇▇▇
▇▇▇▇▇▇▇▇▇, ▇▇ ▇▇▇▇▇
If to ▇▇▇▇ ▇. ▇▇▇▇▇▇, M.D. at:
▇▇▇▇ ▇. ▇▇▇▇▇▇, M.D.
c/o Transcend Therapeutics, Inc.
▇▇▇ ▇▇▇▇▇▇▇▇ ▇▇▇▇▇
▇▇▇ ▇▇▇▇▇ ▇▇▇▇
▇▇▇▇▇▇▇▇▇, ▇▇ ▇▇▇▇▇
IN WITNESS WHEREOF, this Amendment has been executed as of the date first
written above.
TRANSCEND THERAPEUTICS, INC.
By: /s/ ▇▇▇▇▇▇ ▇. ▇▇▇▇▇
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Name: ▇▇. ▇▇▇▇▇▇ ▇. ▇▇▇▇▇, M.D., Ph.D
Title: President
▇▇▇▇▇ ▇. ▇▇▇▇▇▇▇
/s/ ▇▇▇▇▇ ▇. ▇▇▇▇▇▇▇
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▇▇▇▇▇ ▇. ▇▇▇▇▇▇▇
▇▇▇▇▇▇▇ ▇. ▇▇▇▇
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▇▇▇▇▇▇▇ ▇. ▇▇▇▇
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▇▇▇▇▇ ▇. ▇▇▇▇▇▇▇
/s/ ▇▇▇▇▇ ▇. ▇▇▇▇▇▇▇
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▇▇▇▇▇ ▇. ▇▇▇▇▇▇▇
THE VENTURE CAPITAL FUND OF
NEW ENGLAND III, L.P.
By: F H & Co. III, L.P.
General Partner
By: /s/ ▇▇▇▇▇▇▇ ▇. ▇▇▇▇▇ III
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▇▇▇▇▇▇▇ ▇. ▇▇▇▇▇, III
General Partner
SPROUT CAPITAL VI, L.P.
By: DLJ Capital Corporation,
Managing General Partner
By: /s/ ▇▇▇▇▇▇▇▇ ▇▇▇▇▇▇▇
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Name: ▇▇▇▇▇▇▇▇ ▇▇▇▇▇▇▇
Title: Vice President
DLJ CAPITAL CORPORATION
By: /s/ ▇▇▇▇▇▇▇▇ ▇▇▇▇▇▇▇
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Name: ▇▇▇▇▇▇▇▇ ▇▇▇▇▇▇▇
Title: Vice President
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ADVENT INTERNATIONAL INVESTORS II
LIMITED PARTNERSHIP
By: Advent International Corporation,
General Partner
By: /s/ ▇▇▇▇▇▇ ▇. Moufflet
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Name: ▇▇▇▇▇▇ ▇. Moufflet
Title: Senior Vice President
ADVENT PERFORMANCE MATERIALS
LIMITED PARTNERSHIP
By: Advent International Limited
Partnership, General Partner
By: Advent International Corporation,
General Partner
By: /s/ ▇▇▇▇▇▇ ▇. Moufflet
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Name: ▇▇▇▇▇▇ ▇. Moufflet
Title: Senior Vice President
GLOBAL PRIVATE EQUITY II LIMITED
PARTNERSHIP
By: Advent International Limited Partnership,
General Partner
By: Advent International Corporation,
General Partner
By: /s/ ▇▇▇▇▇▇ ▇. Moufflet
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Name: ▇▇▇▇▇▇ ▇. Moufflet
Title: Senior Vice President
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ROVENT II LIMITED PARTNERSHIP
By: Advent International Limited Partnership,
General Partner
By: Advent International Corporation,
General Partner
By: /s/ ▇▇▇▇▇▇ ▇. Moufflet
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Name: ▇▇▇▇▇▇ ▇. Moufflet
Title: Senior Vice President
▇▇▇▇▇▇ HEALTHCARE CORPORATION
By: /s/ ▇▇▇▇ ▇. ▇▇▇▇▇▇▇
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Name: ▇▇▇▇ ▇. ▇▇▇▇▇▇▇, ▇▇.
Title: Vice President
CLINICAL NUTRITION HOLDINGS, INC.
By: /s/ ▇▇▇▇▇▇ ▇. ▇▇▇▇▇▇▇
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Name: ▇▇▇▇▇▇ ▇. ▇▇▇▇▇▇▇
Title: Vice President
CLINTEC INTERNATIONAL, INC.
(HELD IN LIQUIDATING TRUST)
By: /s/ ▇▇▇▇▇▇▇ ▇. ▇▇▇▇
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Name: ▇▇▇▇▇▇▇ ▇. ▇▇▇▇
Title: Vice President
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▇▇▇▇ ▇. ▇▇▇▇▇▇▇
By: /s/ ▇▇▇▇▇▇ ▇. Moufflet
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▇▇▇▇▇▇ ▇. Moufflet as attorney-in-fact
for ▇▇▇▇ ▇. ▇▇▇▇▇▇▇
▇▇▇▇▇▇▇ ▇▇▇
By: /s/ ▇▇▇▇▇▇ ▇. Moufflet
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▇▇▇▇▇▇ ▇. Moufflet as attorney-in-fact
for ▇▇▇▇▇▇▇ ▇▇▇
MASSACHUSETTS INSTITUTE OF
TECHNOLOGY
By:
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Name:
Title:
/s/ ▇▇▇▇▇▇ ▇. ▇▇▇▇▇
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▇▇▇▇▇▇ ▇. ▇▇▇▇▇, M.D.
/s/ ▇▇▇▇ ▇. ▇▇▇▇▇▇
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▇▇▇▇ ▇. ▇▇▇▇▇▇, M.D.
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