Exhibit 10.15.1
AMENDMENT NO. 01
Dated September 30, 2005
TO
that certain Loan and Security Agreement No. 4201
dated as of September 7, 2004, ("AGREEMENT"), by and between
LIGHTHOUSE CAPITAL PARTNERS V, L.P. ("LENDER") AND
COMBINATORX, INCORPORATED ("BORROWER").
(All capitalized terms not otherwise defined herein shall have the meanings
given to such terms in the Agreement.)
Without limiting or amending any other provisions of the Agreement, Lender and
Borrower agree to the following:
SECTION 1.1, the following definitions of the Agreement shall be deleted in its
entirety and replaced with the following:
"COMMITMENT TERMINATION DATE" means the earliest to occur of (I)
October 15, 2005; (II) any Default or Event of Default, or (III) in Lender's
sole judgment, any adverse change in the management or composition of
Borrower's Board of Directors after the date hereof.
Except as amended hereby, the Agreement remains unmodified and unchanged.
BORROWER: LENDER:
COMBINATORX, INCORPORATED LIGHTHOUSE CAPITAL PARTNERS, V, L.P.
By: /s/ ▇. ▇▇▇▇▇▇▇▇▇ By: LIGHTHOUSE MANAGEMENT
PARTNERS V, L.L.C., its general partner
Name: ▇. ▇▇▇▇▇▇▇▇▇
Title: EVP & CFO By: /s/ illegible
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