CUSIP NO. 00000X000 Schedule 13G Page 20 of 24
EXHIBIT 1
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JOINT FILING AGREEMENT PURSUANT TO RULE 13d-1(k)(1)
The undersigned acknowledge and agree that the foregoing
statement on Schedule 13G is filed on behalf of each of the undersigned and
that all subsequent amendments to this statement on Schedule 13G shall be
filed on behalf of each of the undersigned without the necessity of filing
additional joint filing statements. The undersigned acknowledge that each
shall be responsible for the timely filing of such amendments, and for the
completeness and accuracy of the information concerning him, her or it
contained herein, but shall not be responsible for the completeness and
accuracy of the information concerning the other entities or persons, except
to the extent that he, she or it knows or has reason to believe that such
information is inaccurate.
Dated as of February 14, 2006
PERSEUS-XXXXX BIOPHARMACEUTICAL FUND, LP
By: Perseus-Xxxxx Partners, LLC
General Partner
By: SFM Participation, L.P.
Managing Member
By: SFM AH LLC
General Partner
By: Xxxxx Fund Management LLC
Managing Member
By: /s/ Xxxxx X. Xxxxxxxxx
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Name: Xxxxx X. Xxxxxxxxx
Title: Assistant General Counsel
CUSIP NO. 00000X000 Schedule 13G Page 21 of 24
PERSEUS-XXXXX PARTNERS, LLC
By: SFM Participation, L.P.
Managing Member
By: SFM AH LLC
General Partner
By: Xxxxx Fund Management LLC
Managing Member
By: /s/ Xxxxx X. Xxxxxxxxx
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Name: Xxxxx X. Xxxxxxxxx
Title: Assistant General Counsel
PERSEUS BIOTECH FUND PARTNERS, LLC
By: Perseuspur, LLC
Member
By: /s/ Xxxx Xxxxxxx
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Name: Xxxx Xxxxxxx
Title: Secretary and Treasurer
SFM PARTICIPATION, L.P.
By: SFM AH LLC
General Partner
By: Xxxxx Fund Management LLC
Managing Member
By: /s/ Xxxxx X. Xxxxxxxxx
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Name: Xxxxx X. Xxxxxxxxx
Title: Assistant General Counsel
CUSIP NO. 00000X000 Schedule 13G Page 22 of 24
SFM AH LLC
By: Xxxxx Fund Management LLC
Managing Member
By: /s/ Xxxxx X. Xxxxxxxxx
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Name: Xxxxx X. Xxxxxxxxx
Title: Assistant General Counsel
PERSEUSPUR, LLC
By: /s/ Xxxx Xxxxxxx
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Name: Xxxx Xxxxxxx
Title: Secretary and Treasurer
XX. XXXXX X. XXXXX
By: /s/ Xxxx Xxxxxxx
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Name: Xxxx Xxxxxxx
Title: Attorney-in-Fact
MR. XXXXXX XXXXX
By: /s/ Xxxxx X. Xxxxxxxxx
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Name: Xxxxx X. Xxxxxxxxx
Title: Attorney-in-Fact
XXXXX FUND MANAGEMENT LLC
By: /s/ Xxxxx X. Xxxxxxxxx
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Name: Xxxxx X. Xxxxxxxxx
Title: Assistant General Counsel