ANACOR PHARMACEUTICALS, INC. AND , AS WARRANT AGENT FORM OF COMMON STOCK WARRANT AGREEMENT DATED AS OFCommon Stock Warrant Agreement • December 27th, 2011 • Anacor Pharmaceuticals Inc • Pharmaceutical preparations • New York
Contract Type FiledDecember 27th, 2011 Company Industry JurisdictionTHIS COMMON STOCK WARRANT AGREEMENT (this “Agreement”), dated as of [·], between ANACOR PHARMACEUTICALS, INC., a Delaware corporation (the “Company”) and [·], a [corporation] [national banking association] organized and existing under the laws of [·] and having a corporate trust office in [·], as warrant agent (the “Warrant Agent”).
ANACOR PHARMACEUTICALS, INC. [ • ] Shares of Common Stock Underwriting AgreementUnderwriting Agreement • November 12th, 2010 • Anacor Pharmaceuticals Inc • Pharmaceutical preparations • New York
Contract Type FiledNovember 12th, 2010 Company Industry JurisdictionCITIGROUP GLOBAL MARKETS INC. DEUTSCHE BANK SECURITIES INC. As Representatives of the several Underwriters listed in Schedule 1 hereto
3,129,890 Shares ANACOR PHARMACEUTICALS, INC. Common Stock UNDERWRITING AGREEMENTUnderwriting Agreement • April 26th, 2013 • Anacor Pharmaceuticals, Inc. • Pharmaceutical preparations • New York
Contract Type FiledApril 26th, 2013 Company Industry Jurisdiction
ANACOR PHARMACEUTICALS, INC. AND , AS WARRANT AGENT FORM OF PREFERRED STOCK WARRANT AGREEMENT DATED AS OFPreferred Stock Warrant Agreement • December 27th, 2011 • Anacor Pharmaceuticals Inc • Pharmaceutical preparations • New York
Contract Type FiledDecember 27th, 2011 Company Industry JurisdictionTHIS PREFERRED STOCK WARRANT AGREEMENT (this “Agreement”), dated as of [•], between ANACOR PHARMACEUTICALS, INC., a Delaware corporation (the “Company”) and [•], a [corporation] [national banking association] organized and existing under the laws of [•] and having a corporate trust office in [·], as warrant agent (the “Warrant Agent”).
ANACOR PHARAMEUTICALS, INC. AND , AS WARRANT AGENT FORM OF DEBT SECURITIES WARRANT AGREEMENT DATED AS OFSecurities Warrant Agreement • December 27th, 2011 • Anacor Pharmaceuticals Inc • Pharmaceutical preparations • New York
Contract Type FiledDecember 27th, 2011 Company Industry JurisdictionTHIS DEBT SECURITIES WARRANT AGREEMENT (this “Agreement”), dated as of [·], between ANACOR PHARAMEUTICALS, INC., a Delaware corporation (the “Company”) and [•], a [corporation] [national banking association] organized and existing under the laws of [·] and having a corporate trust office in [·], as warrant agent (the “Warrant Agent”).
AGREEMENT AND PLAN OF MERGER dated as of May 14, 2016 among ANACOR PHARMACEUTICALS, INC., PFIZER INC. and QUATTRO MERGER SUB INC.Agreement and Plan of Merger • May 16th, 2016 • Anacor Pharmaceuticals, Inc. • Pharmaceutical preparations • Delaware
Contract Type FiledMay 16th, 2016 Company Industry JurisdictionAGREEMENT AND PLAN OF MERGER (this “Agreement”), dated as of May 14, 2016, among Anacor Pharmaceuticals, Inc., a Delaware corporation (the “Company”), Pfizer Inc., a Delaware corporation (“Parent”), and Quattro Merger Sub Inc., a Delaware corporation and a wholly owned subsidiary of Parent (“Merger Sub”).
INDEMNIFICATION AGREEMENTIndemnification Agreement • November 12th, 2010 • Anacor Pharmaceuticals Inc • Pharmaceutical preparations • Delaware
Contract Type FiledNovember 12th, 2010 Company Industry JurisdictionThis Agreement is made as of , between Anacor Pharmaceuticals, Inc., a Delaware corporation (the "Company"), and (the "Indemnitee").
4,000,000 Shares ANACOR PHARMACEUTICALS, INC. Common Stock UNDERWRITING AGREEMENTUnderwriting Agreement • October 18th, 2012 • Anacor Pharmaceuticals Inc • Pharmaceutical preparations • New York
Contract Type FiledOctober 18th, 2012 Company Industry Jurisdiction
ContractWarrant Agreement • August 9th, 2013 • Anacor Pharmaceuticals, Inc. • Pharmaceutical preparations • California
Contract Type FiledAugust 9th, 2013 Company Industry JurisdictionTHIS WARRANT, AND THE SECURITIES ISSUABLE UPON THE EXERCISE OF THIS WARRANT, HAVE NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE “ACT”), OR ANY STATE SECURITIES LAWS. THEY MAY NOT BE SOLD, OFFERED FOR SALE, PLEDGED, OR HYPOTHECATED IN THE ABSENCE OF AN EFFECTIVE REGISTRATION STATEMENT RELATED THERETO OR AN OPINION OF COUNSEL (WHICH MAY BE COMPANY COUNSEL) REASONABLY SATISFACTORY TO THE COMPANY THAT SUCH REGISTRATION IS NOT REQUIRED UNDER THE ACT, OR ANY APPLICABLE STATE SECURITIES LAWS.
ContractAnacor Pharmaceuticals Inc • September 10th, 2010 • Pharmaceutical preparations • California
Company FiledSeptember 10th, 2010 Industry JurisdictionTHIS WARRANT HAS NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE "1933 ACT"), OR ANY APPLICABLE STATE SECURITIES LAWS, AND MAY NOT BE SOLD OR TRANSFERRED UNLESS SUCH SALE OR TRANSFER IS IN ACCORDANCE WITH THE REGISTRATION REQUIREMENTS OF SUCH ACT AND APPLICABLE LAWS OR SOME OTHER EXEMPTION FROM THE REGISTRATION REQUIREMENTS OF SUCH ACT AND APPLICABLE LAWS IS AVAILABLE WITH RESPECT THERETO.
ANACOR PHARMACEUTICALS, INC. EQUITY DISTRIBUTION AGREEMENTEquity Distribution Agreement • March 18th, 2013 • Anacor Pharmaceuticals Inc • Pharmaceutical preparations • New York
Contract Type FiledMarch 18th, 2013 Company Industry Jurisdiction
ContractAnacor Pharmaceuticals Inc • November 9th, 2012 • Pharmaceutical preparations • California
Company FiledNovember 9th, 2012 Industry JurisdictionTHIS WARRANT AND THE SHARES ISSUABLE HEREUNDER HAVE NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE “ACT”), OR THE SECURITIES LAWS OF ANY STATE AND, EXCEPT AND PURSUANT TO THE PROVISIONS OF ARTICLE 5 BELOW, MAY NOT BE OFFERED, SOLD OR OTHERWISE TRANSFERRED, PLEDGED OR HYPOTHECATED UNLESS AND UNTIL REGISTERED UNDER SAID ACT AND APPLICABLE STATE SECURITIES LAW OR, IN THE OPINION OF LEGAL COUNSEL IN FORM AND SUBSTANCE SATISFACTORY TO THE ISSUER OF THESE SECURITIES, SUCH OFFER, SALE OR TRANSFER, PLEDGE OR HYPOTHECATION IS EXEMPT FROM REGISTRATION.
FORM OF LOCK-UP AGREEMENTUp Agreement • December 10th, 2010 • Anacor Pharmaceuticals Inc • Pharmaceutical preparations • New York
Contract Type FiledDecember 10th, 2010 Company Industry JurisdictionThe undersigned understands that you, as Representatives of the several Underwriters, propose to enter into an Underwriting Agreement (the “Underwriting Agreement”) with Anacor Pharmaceuticals, Inc., a Delaware corporation (the “Company”), providing for the public offering (the “Public Offering”) by the several Underwriters named in Schedule 1 to the Underwriting Agreement (the “Underwriters”), of Common Stock of the Company (the “Securities”) pursuant to a Registration Statement on Form S-1 to be filed with the Securities and Exchange Commission (the “Registration Statement”). Capitalized terms used herein and not otherwise defined shall have the meanings set forth in the Underwriting Agreement.
COMMON STOCK PURCHASE AGREEMENTCommon Stock Purchase Agreement • March 29th, 2011 • Anacor Pharmaceuticals Inc • Pharmaceutical preparations • California
Contract Type FiledMarch 29th, 2011 Company Industry JurisdictionTHIS COMMON STOCK PURCHASE AGREEMENT (this “Agreement”) is dated as of November 23, 2010, by and among Anacor Pharmaceuticals, Inc., a Delaware corporation (the “Company”), and each purchaser identified on the signature pages hereto (each, including its successors and assigns, a “Purchaser” and collectively, the “Purchasers”).
ANACOR PHARMACEUTICALS, INC. A DELAWARE CORPORATION REGISTRATION RIGHTS AGREEMENT November 23, 2010Registration Rights Agreement • March 29th, 2011 • Anacor Pharmaceuticals Inc • Pharmaceutical preparations • California
Contract Type FiledMarch 29th, 2011 Company Industry JurisdictionThis Registration Rights Agreement (this “Agreement”) is made as of November 23, 2010, by and among Anacor Pharmaceuticals, Inc., a Delaware corporation (the “Company”) and the investors listed on Exhibit A hereto (each, an “Investor”).
ANACOR PHARMACEUTICALS, INC. CHANGE OF CONTROL AND SEVERANCE AGREEMENTAnacor Pharmaceuticals Inc • April 3rd, 2008 • Pharmaceutical preparations • California
Company FiledApril 3rd, 2008 Industry JurisdictionThis Change of Control and Severance Agreement (the "Agreement") is dated as of [ ], by and between ("Employee") and Anacor Pharmaceuticals, Inc., a Delaware corporation (the "Company" or "Anacor"). This Agreement is intended to provide Employee with certain benefits described herein upon the occurrence of specific events.
LOAN AND SECURITY AGREEMENTLoan and Security Agreement • October 9th, 2007 • Anacor Pharmaceuticals Inc • Pharmaceutical preparations • California
Contract Type FiledOctober 9th, 2007 Company Industry JurisdictionTHIS LOAN AND SECURITY AGREEMENT NO. 5251 (this "Agreement") is entered into as of June 30, 2006, by and between LIGHTHOUSE CAPITAL PARTNERS V, L.P. ("Lender") and ANACOR PHARMACEUTICALS, INC., a Delaware corporation ("Borrower") and sets forth the terms and conditions upon which Lender will lend and Borrower will repay money. In consideration of the mutual covenants herein contained, the parties agree as follows:
ContractAnacor Pharmaceuticals, Inc. • August 9th, 2013 • Pharmaceutical preparations • California
Company FiledAugust 9th, 2013 Industry JurisdictionTHIS WARRANT HAS NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE “1933 ACT”), OR ANY APPLICABLE STATE SECURITIES LAWS, AND MAY NOT BE SOLD OR TRANSFERRED UNLESS SUCH SALE OR TRANSFER IS IN ACCORDANCE WITH THE REGISTRATION REQUIREMENTS OF SUCH ACT AND APPLICABLE LAWS OR SOME OTHER EXEMPTION FROM THE REGISTRATION REQUIREMENTS OF SUCH ACT AND APPLICABLE LAWS IS AVAILABLE WITH RESPECT THERETO.
ANACOR PHARMACEUTICALS, INC. CHANGE OF CONTROL AND SEVERANCE AGREEMENTChange of Control and Severance Agreement • September 10th, 2010 • Anacor Pharmaceuticals Inc • Pharmaceutical preparations • California
Contract Type FiledSeptember 10th, 2010 Company Industry JurisdictionThis Change of Control and Severance Agreement (the "Agreement") is dated as of August 21, 2007, by and between David P. Perry ("Employee") and Anacor Pharmaceuticals, Inc., a Delaware corporation (the "Company" or "Anacor"). This Agreement is intended to provide Employee with certain benefits described herein upon the occurrence of specific events.
RESEARCH AND DEVELOPMENT COLLABORATION, OPTION AND LICENSE AGREEMENT BETWEEN SMITHKLINE BEECHAM CORPORATION D/B/A GLAXOSMITHKLINE and ANACOR PHARMACEUTICALS, INC.Research and Development Collaboration, Option and License Agreement • October 26th, 2010 • Anacor Pharmaceuticals Inc • Pharmaceutical preparations • New York
Contract Type FiledOctober 26th, 2010 Company Industry JurisdictionThis RESEARCH AND DEVELOPMENT COLLABORATION, OPTION AND LICENSE AGREEMENT (the "Agreement") is entered into and made effective as of the 5th day of October, 2007 (the "Effective Date") by and between Anacor Pharmaceuticals, Inc., a Delaware corporation having its principal place of business at 1060 East Meadow Circle, Palo Alto, CA 94303 ("Anacor"), and SmithKline Beecham Corporation d/b/a GlaxoSmithKline, a Pennsylvania corporation having offices at One Franklin Plaza, Philadelphia, PA 19101 ("GSK"). Anacor and GSK are each referred to herein by name or as a "Party" or, collectively, as "Parties."
ANACOR PHARMACEUTICALS, INC. 3,250,000 Shares Common Stock ($0.001 par value) Underwriting AgreementUnderwriting Agreement • February 9th, 2012 • Anacor Pharmaceuticals Inc • Pharmaceutical preparations • New York
Contract Type FiledFebruary 9th, 2012 Company Industry Jurisdiction
ANACOR PHARMACEUTICALS, INC. CHANGE OF CONTROL AND SEVERANCE AGREEMENTControl and Severance Agreement • September 10th, 2010 • Anacor Pharmaceuticals Inc • Pharmaceutical preparations • California
Contract Type FiledSeptember 10th, 2010 Company Industry JurisdictionThis Change of Control and Severance Agreement (the "Agreement") is dated as of [ ], by and between ("Employee") and Anacor Pharmaceuticals, Inc., a Delaware corporation (the "Company" or "Anacor"). This Agreement is intended to provide Employee with certain benefits described herein upon the occurrence of specific events.
CONFIDENTIALITY AGREEMENT April 19, 2016Confidentiality Agreement • May 26th, 2016 • Anacor Pharmaceuticals, Inc. • Pharmaceutical preparations • Delaware
Contract Type FiledMay 26th, 2016 Company Industry JurisdictionIn connection with your consideration of a possible transaction involving Anacor Pharmaceuticals, Inc. (the “Company”) and Pfizer Inc. (“Pfizer”) (the “Transaction”), it is expected that each party may furnish or otherwise make available (the “Disclosing Party”) certain information regarding the Disclosing Party’s business, operations and affairs to the other party (the “Receiving Party”). Such information (whether oral, written, electronic or otherwise), regardless of the form in which it is provided or maintained and whether prepared by the Disclosing Party, its Representatives (as defined below) or otherwise and whether provided on or after the date hereof, together with those portions of any notes, analyses, compilations, studies, interpretations or other documents prepared by the Receiving Party or any of the Receiving Party’s Representatives that contain or otherwise reflect such information is hereinafter referred to as “Confidential Information,” except that “Confidential Infor
SUPPLEMENTAL INDENTURESupplemental Indenture • June 24th, 2016 • Anacor Pharmaceuticals, Inc. • Pharmaceutical preparations • New York
Contract Type FiledJune 24th, 2016 Company Industry JurisdictionSUPPLEMENTAL INDENTURE (the “Supplemental Indenture”), dated as of June 24, 2016, to the Indenture (defined below) by and among Anacor Pharmaceuticals, Inc., a Delaware corporation (the “Company”), and Wells Fargo Bank, National Association, a national banking association, as Trustee under the Indenture (the “Trustee”).
Contract’ Rights Agreement • November 9th, 2012 • Anacor Pharmaceuticals Inc • Pharmaceutical preparations • California
Contract Type FiledNovember 9th, 2012 Company Industry JurisdictionTHIS WARRANT AND THE SHARES ISSUABLE HEREUNDER HAVE NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE “ACT”), OR THE SECURITIES LAWS OF ANY STATE AND, EXCEPT AND PURSUANT TO THE PROVISIONS OF ARTICLE 5 BELOW, MAY NOT BE OFFERED, SOLD OR OTHERWISE TRANSFERRED, PLEDGED OR HYPOTHECATED UNLESS AND UNTIL REGISTERED UNDER SAID ACT AND APPLICABLE STATE SECURITIES LAW OR, IN THE OPINION OF LEGAL COUNSEL IN FORM AND SUBSTANCE SATISFACTORY TO THE ISSUER OF THESE SECURITIES, SUCH OFFER, SALE OR TRANSFER, PLEDGE OR HYPOTHECATION IS EXEMPT FROM REGISTRATION.
ContractAnacor Pharmaceuticals Inc • September 10th, 2010 • Pharmaceutical preparations • California
Company FiledSeptember 10th, 2010 Industry JurisdictionTHIS WARRANT HAS NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE "1933 ACT"), OR ANY APPLICABLE STATE SECURITIES LAWS, AND MAY NOT BE SOLD OR TRANSFERRED UNLESS SUCH SALE OR TRANSFER IS IN ACCORDANCE WITH THE REGISTRATION REQUIREMENTS OF SUCH ACT AND APPLICABLE LAWS OR SOME OTHER EXEMPTION FROM THE REGISTRATION REQUIREMENTS OF SUCH ACT AND APPLICABLE LAWS IS AVAILABLE WITH RESPECT THERETO.
AMENDMENT 4 TO ANACOR PHARMACEUTICALS, INC. ADVISORY BOARD AGREEMENTAdvisory Board Agreement • March 16th, 2015 • Anacor Pharmaceuticals, Inc. • Pharmaceutical preparations
Contract Type FiledMarch 16th, 2015 Company IndustryThis Amendment, effective January 1, 2014 (the “Effective Date”), is to Advisory Board Agreement commencing October 1, 2005, and any subsequent Amendments (the “Agreement”) between Anacor Pharmaceuticals, Inc. (“Company”) and Lucy Shapiro, Ph.D. (“Advisor”), together, the Parties.
FIRST AMENDMENT TO LEASELease • August 9th, 2013 • Anacor Pharmaceuticals, Inc. • Pharmaceutical preparations
Contract Type FiledAugust 9th, 2013 Company IndustryTHIS FIRST AMENDMENT TO LEASE (the “Amendment”) is made and entered into as of the date below written by and between CALIFORNIA PACIFIC COMMERCIAL CORPORATION, a California corporation (“Landlord”) and ANACOR PHARMACEUTICALS, INC., a Delaware corporation (“Tenant”).
Confidential Separation Agreement and General Release of Claims Dear Chris:Anacor Pharmaceuticals Inc • September 10th, 2010 • Pharmaceutical preparations • California
Company FiledSeptember 10th, 2010 Industry JurisdictionThis letter confirms the agreement between you and Anacor Pharmaceuticals, Inc. (the "Company") concerning the terms of your resignation and separation from the Company and offers you the consulting arrangement we discussed in exchange for a release of claims.
ANACOR PHARMACEUTICALS, INC. COMMON STOCK PURCHASE AGREEMENT April 5, 2013Common Stock Purchase Agreement • April 8th, 2013 • Anacor Pharmaceuticals Inc • Pharmaceutical preparations • New York
Contract Type FiledApril 8th, 2013 Company Industry JurisdictionTHIS COMMON STOCK PURCHASE AGREEMENT (the “Agreement”) is made and entered into as of April 5, 2013, by and between ANACOR PHARMACEUTICALS, INC., a Delaware corporation (the “Company”) and the Bill & Melinda Gates Foundation (the “Foundation”).
QuickLinks -- Click here to rapidly navigate through this documentAnacor Pharmaceuticals Inc • August 31st, 2007 • Delaware
Company FiledAugust 31st, 2007 JurisdictionIn partial consideration of Anacor Pharmaceuticals, Inc.'s (the "Company") agreement to enter into that certain License, Development, and Commercialization Agreement, between Schering Corporation ("Schering") and the Company, dated as of February , 2007 (the "License Agreement"), this letter relates to our agreement pursuant to Section 9.2 of the License Agreement with regard to the commitment of Schering to purchase up to $10,000,000 in the Company's equity securities, subject to the terms and conditions set forth in this letter (the "Schering Investment").
QuickLinks -- Click here to rapidly navigate through this documentPreferred Stock Purchase • October 9th, 2007 • Anacor Pharmaceuticals Inc • Pharmaceutical preparations • California
Contract Type FiledOctober 9th, 2007 Company Industry JurisdictionTHIS WARRANT HAS NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE "1933 ACT"), OR ANY APPLICABLE STATE SECURITIES LAWS, AND MAY NOT BE SOLD OR TRANSFERRED UNLESS SUCH SALE OR TRANSFER IS IN ACCORDANCE WITH THE REGISTRATION REQUIREMENTS OF SUCH ACT AND APPLICABLE LAWS OR SOME OTHER EXEMPTION FROM THE REGISTRATION REQUIREMENTS OF SUCH ACT AND APPLICABLE LAWS IS AVAILABLE WITH RESPECT THERETO.
ANACOR PHARMACEUTICALS, INC. CONSULTING AGREEMENTConsulting Agreement • September 10th, 2010 • Anacor Pharmaceuticals Inc • Pharmaceutical preparations • California
Contract Type FiledSeptember 10th, 2010 Company Industry JurisdictionThis Consulting Agreement (the "Agreement") is entered into by and between Anacor Pharmaceuticals, Inc., a Delaware corporation (the "Company"), and Stephen J. Benkovic, Ph.D. ("Consultant").
ANACOR PHARMACEUTICALS, INC. CHANGE OF CONTROL AND SEVERANCE AGREEMENT [VP FORM]Change of Control and Severance Agreement • March 15th, 2012 • Anacor Pharmaceuticals Inc • Pharmaceutical preparations • California
Contract Type FiledMarch 15th, 2012 Company Industry JurisdictionThis Change of Control and Severance Agreement (the “Agreement”) is dated as of , by and between (“Employee”) and Anacor Pharmaceuticals, Inc., a Delaware corporation (the “Company” or “Anacor”). This Agreement is intended to provide Employee with certain benefits described herein upon the occurrence of specific events.
CONSULTING AGREEMENTConsulting Agreement • September 10th, 2010 • Anacor Pharmaceuticals Inc • Pharmaceutical preparations • California
Contract Type FiledSeptember 10th, 2010 Company Industry JurisdictionThis CONSULTING AGREEMENT is effective as of April 13, 2010 ("Agreement") between Anacor Pharmaceuticals, Inc. ("Company") and Christine Gray-Smith ("Consultant"). Company and Consultant are collectively the Parties and each a Party.