Severe Clause Samples
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Severe. The term “severe” refers to the intensity of the harm caused to the environment, independent of its geographic ambit or temporal duration. Severe environmental harm denotes damage 490 Secretary-General Report 1993, pp.7; ▇▇▇▇▇▇▇ (1997), pp.71, 107. See also, e.g. Australia, The Manual of the Law of Armed Conflict, Australian Defence Doctrine Publication, 06.4, Australian Defence Headquarters, 11 May 2006, para. 7.14 (noting that long-term had been interpreted to mean a period of decades). 491 ▇▇▇▇▇▇▇▇ (2001), p.536. 492 Final Report on NATO (2000), para.15. 493 See for example ▇▇▇▇▇ ▇▇▇▇▇▇▇▇, The Conduct of Hostilities under the Law of International Armed Conflict (Cambridge University Press: Cambridge, 2004), p.194, cited in ▇▇▇▇▇▇▇▇ (2009), p.342. 494 United States, Department of Defense, “Final Report to Congress on the Conduct of the Persian Gulf War, Appendix O, The Role of the Law in War”, 10 April 1992, ILM, Vol. 31, pp.636-637. 495 Secretary-General Report 1993, p.7. going beyond typical battlefield damage.496 Examples of environmental harm that has been described as sufficiently severe include the “dam-buster” raids in World War II. The raids destroyed the Mohne and ▇▇▇▇ dams in order to cut off water from the Ruhr industrial complex. They resulted in the death of more than 1300 civilians and cut off drinking water and energy to 4 million Germans.497 UNEP suggests that this element should be interpreted as “serious or significant disruption or harm to human life, natural economic resources or other assets.”498 There are distinct examples in recent times of commanders launching attacks that resulted in serious environmental harm. For example, UNEP noted that thousands of tons of fuel oil were released into the Mediterranean Sea after the bombing of the Jiyeh power station during the conflict between Israel and Lebanon in 2006.499 Similarly, the current armed conflict in Syria is having a deleterious environmental impact in Syria and Lebanon, including through increased pollution and degradation of surface, ground and marine water.500 In assessing the severity of the harm, the analysis should encompass the direct environmental harm caused by the attack as well as secondary effects. For example, when detailing the harm caused by ▇▇▇▇▇▇ ▇▇▇▇▇▇▇’▇ forces setting fire to the Kuwaiti oil ▇▇▇▇▇, the United Nations Compensation Commission for Iraq took into account a range of factors going beyond the immediate incineration of the oil. Additional environmen...
Severe. Hepatic impairment Mild Since Azathioprine pharmacokinetics has not been formally studied in hepatic impairment, no specific dose recommendations can be given. Since impaired hepatic function may result in reduced elimination of Azathioprine and its metabolites, consideration should be given to reducing the starting doses in patients with impaired hepatic function. Patients should be monitored for dose related adverse effects. Moderate Severe Contra-indications / Special precautions Please refer to SPC Side Effects Very common Bone marrow depression, leukopenia. Common Thrombocytopenia, nausea. Monitoring Pre-treatment assessment TPMT test (ThioPurine MethylTransferase) and Hepatitis B serology should be performed at baseline, (specialist responsibility). Full blood count, urea and electrolytes, liver function tests, bone profile should be performed weekly for the first 8 weeks, until dose is stable. After commencing treatment Once dose is stable, full blood count, urea and electrolytes, liver function tests and bone profile should be monitored every 3 months during treatment. Actions to be taken: Worsening of anaemia. Discuss with specialist team. Neutrophils < 1.5 x 109/L Discuss with specialist team. Platelets < 100 x 109/L Discuss with specialist team. Abnormal LFT’s, (ALT / AST > 2 x ULN, or any deranged Bilirubin). Discuss with specialist team. Unexplained drop in eGFR from baseline. Discuss with specialist team. Drug Interactions Please refer to SPC
Severe. Incident causing inoperative Software or preventing use of major Software functions Acknowledgment Incident analysis Patch, temporary fix Final fix Communications Less than 2 hours Within 24 hours Continuous efforts until resolved Continuous efforts until resolved Continuously through Business Hours
Severe. Loss of service or severely degraded network performance that affects the entire unit, an entire building, or a critical application.
Severe the service is completely inaccessible or major features are not functional (This is the only level of performance defect that counts as downtime.)
Severe. Important Licensed Product features are unavailable with no workaround available. Licensee’s ability to conduct business is seriously affected. Licensor will provide a workaround that resolves the request, provided that, if Licensor is unable to provide a workaround, Licensor will classify the request as an Error in the Licensed Products and work to produce a Corrected Release in accordance with the Service ▇▇▇▇▇ ▇▇ ▇▇▇ ▇▇▇▇▇▇▇▇.
Severe. Events interrupt the patient’s normal daily activities and generally require systemic drug therapy or other treatment; they are usually incapacitating. To make sure there is no confusion or misunderstanding of the difference between the terms “serious” and “severe,” which are not synonymous, the following note of clarification is provided. The term “severe” is often used to describe the intensity (severity) of a specific event (as in mild, moderate, or severe myocardial infarction); the event itself, however, maybe of relatively minor medical significance (such as severe headache). This is not the same as “serious,” which is based on patient/event outcome or action criteria usually associated with events that pose a threat to a patient's life or functioning. Seriousness (not severity) serves as a guide for defining regulatory reporting obligations.
Severe. Any Error that causes or results in: (i) functional inconsistency across the System; and/or (ii)
Severe. Any areas that have a temperature differential greater than 50°F are deemed as severe thermal segregation.
Severe. The problem has a significant impact on business and/or an important feature is unavailable. • Resolution Handling – Upon receipt of the initial service request, a support agent will be as- signed to your request within 24 hours. Follow up communication from the assigned agent will occur within 48 hours.