Common use of Reagents Clause in Contracts

Reagents. All remaining reagents stored at 2-8C, -20C and -80C. Reagents for KBRV201 include expression vectors for production of intact KBRV201 antibody by transient transfection of mammalian cell lines. All KBAB401 hybridoma and LCL cell lines (uncharacterized) Kenta Biotech, Schlieren, CH All remaining human PBLS stored in LN2 and all patient sera stored at -20C (see document “Freezer Content”). LA55 fusion partner cell line (RCB) Kenta Biotech, Schlieren, CH HL60 phagocytic cell line Ke▇▇▇ ▇▇▇▇▇▇▇, ▇▇▇▇▇▇▇▇▇, ▇▇ ▇▇▇-▇ ▇BV secreting cell line Kenta Biotech, Schlieren, CH EL4-B5 murine feeder cell line Kenta Biotech, Schlieren, CH Patients PBL Kenta Biotech, Schlieren, CH Commercially available cell lines (Jurkat, HEK293, etc.) Kenta Biotech, Schlieren, CH See list of LN2 storage tank Kenta Biotech, Schlieren, CH Kenta Biotech, Schlieren, CH All remaining reagents stored at 2-8C, -20C and -80C (see document “Freezer Content”), including clinical isolates of viruses (RSV) and bacteria (P. aeruginosa, S. aureus, A. baumannii); Patients sera and clinical isolates (BAL, ETA and sputum) from all research activities. · ORION Clinical Services Limited, 7 ▇▇▇▇ ▇▇▇▇, ▇▇▇▇▇▇, ▇▇▇▇▇▇▇ ▇▇▇ ▇▇▇ · ▇▇▇▇▇▇ Clinical Services Switzerland, St▇▇▇▇▇▇▇▇▇▇ ▇▇, ▇▇▇▇ ▇▇▇▇▇▇▇▇▇ / ▇▇▇▇▇▇▇▇▇▇▇ · Cenduit LLC, Chelsea Place, 10▇▇ ▇▇▇▇▇▇ ▇▇▇▇, Suite 301, Durham, NC 27703, USA · Eurofins Medinet B.▇., ▇▇▇▇▇▇▇▇▇ ▇▇, ▇▇▇▇ ▇▇, ▇▇▇▇▇, ▇▇▇ ▇▇▇▇▇▇▇▇▇▇▇ ORION Amendment No 5 to Work Order 001 expected Amendment No 4 to Work Order 001 Mar 27, 2013 Amendment No 3 to Work Order 001 Mar 26, 2013 Amendment No 2 to Work Order 001 Feb 1, 2013 Amendment No 1 to Work Order 001 Feb 1, 2013 Work Order 001 Feb 1, 2012 Master Study Agreement Dec 8, 2011 ▇▇▇▇▇▇ Order 7, Vers. 2; FCS No 205523, Quote relabeling May 21, 2012 Order 1, Vers. 2; FCS No 207727, Quote LN2 storage, back ups May 14, 2012 Order 4, Vers. 2; FCS No 205523, Quote Logistics Feb 1, 2012 Order 6, Vers. 1; FCS No 205523, Quote Label- and Packaging Jan 31, 2012 Responsibilities Agreement (GMP) Nov 18, 2010 Cenduit IRT Change Order Pricing Mar 27, 2012 Individual Project Agreement Feb 24, 2012 IRT Pricing Proposal Feb 15, 2012 Master Project Agreement Dec 20, 2011 Eurofins Change Order 1 to Study Agreement Apr 11, 2012 Study Agreement Dec 20, 2011 Clinical Sites Cliniques Universitaires St Luc, 10 avenue Hippocrate, 1200 Brussels, Belgium Jun 12 Clinique Sa▇▇▇-▇▇▇▇▇▇ ▇, ▇▇▇▇▇▇ ▇▇▇▇▇ ▇▇▇▇▇▇▇, 1340 Ottignies, Belgium Jun 12 University Hospital of Liege, CHU Sart Tilman, Avenue de I’Hopital, n°1, 4000, Liege, Belgium Jun 12 ▇▇▇▇▇▇▇▇▇▇ ▇▇▇▇▇▇▇▇ ▇▇▇▇-▇▇▇▇▇▇▇, ▇▇▇▇▇▇ ▇octeur ▇. ▇▇▇▇▇▇▇▇ 1, 5530 Yvoir, Belgium Jun 12 Le Centre Hospitalier Universitaire de Limoges, 2 Avenue ▇▇▇▇▇▇ ▇▇▇▇▇▇ ▇▇▇▇, 87 042 Limoges Cedex, France Mar 12 Le CENTRE HOSPITALIER ▇▇▇▇▇▇ ▇▇▇▇▇▇ 69, rue du Lieutenant Colonel Prudhon, 95107 Argenteuil, France Apr 12 Le CENTRE HOSPITALIER REGIONAL ET UNIVERSITAIRE DE TOURS, 2 boulevard Tonnelle, 37044 Tours Cedex, France Apr 12 I’Hopital ▇▇▇▇▇ ▇▇▇▇▇▇▇, 178, rue des Renouillers, 92700 Colombes, France May 12 ▇▇▇ ▇▇▇ ▇▇▇▇▇▇▇▇▇, ▇▇▇▇▇ ▇▇ ▇▇▇▇▇ ▇▇▇ Yon Cedex 9 Apr 12 Centre Hospitalier Universitaire de DIJON, 1, bd ▇▇▇▇▇▇ d’Arc, BP 77908, 21079 Dijon Cedex, France Jun 12 Le CENTRE HOSPITALIER UNIVERSITAIRE de NANTES, 5 allee de I’Ile Gloriette, 44093 Nantes, Cedex 1, France May 12 I’Hopital de Ia source 14, avenue de I’hopital - CHR Orleans - BP, 86709 - 47067 Orléans Cedex, France Apr 12 UNIVERSITE ▇▇▇▇▇▇ ▇▇▇▇▇▇▇ ▇▇▇▇ 1, 69100 Villerbanne, France Aug 12 CENTRE HOSPITALIER D’ANGOULEME, 16470 Saint-Michel, France Jul 12 CHU Angers, 4 rue Larrey, 49933 Angers cedex, France Sep 12 Hospital Universitari Vall d’Hebron, Passeig Vall d’Hebron 119-129 , 08035 Barcelona, Spain Jun 12 Hospital Universitario de Bellvitge (HUB) , C/ ▇▇▇▇▇ ▇▇▇▇▇▇, ▇/▇ ▇▇ ▇▇▇▇▇▇▇▇▇▇ ▇▇ ▇▇▇▇▇▇▇▇▇, ▇▇▇▇▇ ▇lobregat, Spain May 12 Doctor ▇▇▇▇▇▇ University Hospital of Gran Canaria c/ ▇▇▇- ▇▇▇▇▇ de la Ballena s/n 35010, Las Palmas, Spain Jul 12 Son Espases Hospital, Ctra Valldemossa 79, 07010 Palma — Balearic Islands, Spain Jul 12 HOSPITAL Universitario de Getafe, Ctra. de Toledo, Km. 12,500, Getafe de Madrid, Spain Nov 12 ▇▇▇▇▇▇▇▇ ▇▇▇▇▇▇▇▇▇▇▇▇▇ ▇▇ ▇▇▇, Pº. Castellana 261, Madrid, 28046, Spain Jun 12 Hospital Universitario Marqués de Valdecilla, Avenida de Valdecilla s/n. 39008-Santander, Spain Jul 12 LA FUNDACION PARA EL FOMENTO DE LA INVESTIGACION SANITARIA Y BIOMEDICA DE LA COMUNIDAD VALENCIANA (FISABIO) C/ ▇▇▇▇▇ ▇▇▇▇▇ No. 31, 46010 -Valencia, Spain Jul 12 Data Monitoring Committee ▇▇▇▇ ▇▇▇▇▇▇ ▇▇▇▇▇▇▇ ▇▇▇▇, USA May 10 Prof Jean Chastre, France Jan 12 ▇▇ ▇▇▇▇▇▇▇▇ ▇▇▇▇▇▇▇▇, Switzerland Oct 11 · All preclinical reports and R&D reports for the KBPA101-104 research projects (electronic and hard copies) · All regulatory documents for the KBPA101-104 projects (electronic and hard copies) · All clinical documents for the KBPA101 project (phase I and phase II), (electronic (if available) and hard copies), including trials-master-files and case-report-forms (only hard copies) · All documents, reports and SOP regarding the diagnostic kit · All raw data stored electronically related to KBPA101 — KBPA104 · All preclinical reports and R&D reports for the KBSA301 research projects (electronic and hard copies) · All regulatory documents for the KBSA301 projects (electronic and hard copies) · All clinical documents for the KBSA301 project (ongoing phase I/II studies), (electronic (if available) and hard copies) · All raw data stored electronically related to KBSA301 · All R&D reports for the KBRV201 research project (electronic and hard copies) · All raw data stored electronically related to KBRV201 · All preclinical reports and R&D reports for the KBAB401 research project (electronic and hard copies) · All raw data stored electronically related to KBAB401