Common use of PROSPECTUS SUMMARY Clause in Contracts

PROSPECTUS SUMMARY. This summary highlights certain information about us, this offering and selected information contained elsewhere in or incorporated by reference into this prospectus. This summary is not complete and does not contain all of the information that you should consider before deciding whether to invest in the securities covered by this prospectus. For a more complete understanding of Aprea and this offering, we encourage you to read and consider carefully the more detailed information in this prospectus, including the information incorporated by reference in this prospectus and the information included in any free writing prospectus that we have authorized for use in connection with this offering, including the information referred to under the heading “Risk Factors” in this prospectus beginning on page S-6.

PROSPECTUS SUMMARY. This summary highlights certain information about us, this offering and selected information contained elsewhere in or incorporated by reference into this prospectus. This summary is not complete and does not contain all of the information that you should consider before deciding whether to invest in the securities covered by this prospectusour common stock. For a more complete understanding of Aprea our company and this offering, we encourage you to read and consider carefully the more detailed information in this prospectus, including the information incorporated by reference in into this prospectus and the information included in any free writing prospectus that we have authorized for use in connection with this offering, including the information referred to contained in and incorporated by reference under the heading “Risk Factors” in this prospectus beginning on page S-6S-5 of this prospectus, and under similar headings in the other documents that are filed after the date hereof and incorporated by reference into this prospectus.