Processing Orders. From time to time as detailed herein, Scios shall submit to Abbott Processing Orders in substantially the form of Exhibit A for such quantities of Product as Scios requests. 2.2.1 Scios shall, within [*****] after filing its NDA for the Product, provide Abbott with a written estimate of Scios’ monthly orders for the Product from Abbott for the first contract year. Abbott acknowledges that such quantities are estimates only. 2.2.2 Abbott and Scios shall cooperate fully in estimating and scheduling production for the first commercial order to be placed by Scios in anticipation of FDA approval of the Product. 2.2.3 Scios shall place its first firm Purchase Order approximately [*****] in advance of the anticipated NDA approval date or desired Product availability date. At the same time, Scios shall provide to Abbott Scios’ estimate of its monthly orders for [*****]. 2.2.4 Thereafter, Scios shall provide [*****] to Abbott a [*****] forecast of orders with the [*****] consisting of firm Purchase Orders and the [*****] consisting of Scios’ best estimate forecast of its Product orders. Within [*****], Abbott shall advise Scios of the date Abbott will perform the Fill and Finish Work specified by such forecast. Each Processing Order submitted by Scios to Abbott shall reference the Fill and Finish date provided by Abbott in ***** Confidential portions of this material have been omitted and filed separately with the Securities and Exchange Commission.
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Processing Orders. From time to time as detailed herein, Scios shall submit to Abbott Processing Orders in substantially the form of Exhibit A for such quantities of Product as Scios requests.
2.2.1 Scios shall, within [*****] after filing its NDA for the Product, provide Abbott with a written estimate of Scios’ ' monthly orders for the Product from Abbott for the first contract year. Abbott acknowledges that such quantities are estimates only.
2.2.2 Abbott and Scios shall cooperate fully in estimating and scheduling production for the first commercial order to be placed by Scios in anticipation of FDA approval of the Product.
2.2.3 Scios shall place its first firm Purchase Order approximately [*****] in advance of the anticipated NDA approval date or desired Product availability date. At the same time, Scios shall provide to Abbott Scios’ ' estimate of its monthly orders for [*****].
2.2.4 Thereafter, Scios shall provide [*****] to Abbott a [*****] forecast of orders with the [*****] consisting of firm Purchase Orders and the [*****] consisting of Scios’ ' best estimate forecast of its Product orders. Within [*****], Abbott shall advise Scios of the date Abbott will perform the Fill and Finish Work specified by such forecast. Each Processing Order submitted by Scios to Abbott shall reference the Fill and Finish date provided by Abbott in response to the most recent forecast and shall become firm and non-cancelable by Scios if not modified by notice from Scios to Abbott [*****].
2.2.5 If, due to significant unforeseen circumstances, Scios requests changes to firm orders [*****], Abbott shall attempt within reasonable manufacturing capabilities and ***** Confidential portions of this material have been omitted and filed separately with the Securities and Exchange Commission.
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