Peroxiredoxins Clause Samples

Peroxiredoxins. Peroxiredoxins are a ubiquitous family of antioxidant enzymes. They are divided into three classes namely typical 2-Cys, atypical 2-Cys and 1-Cys. These enzymes share the same basic catalytic mechanism, in which a redox-active cysteine (the peroxidatic cysteine) in the active site is oxidized to a sulfenic acid by the peroxide substrate(▇▇▇▇▇▇▇▇▇ et al., 1999). The recycling of the sulfenic acid is what distinguishes the three enzyme classes. 2-Cys peroxiredoxins are reduced by thiols such as glutathione, while the 1-Cys enzymes may be reduced by ascorbic acid or glutathione (▇▇▇▇▇▇▇▇ et al., 2007). 1.6.3.1 Glutathione