Common use of Officer Certificate Clause in Contracts

Officer Certificate. The undersigned, the duly qualified and elected _______________________, of Otonomy, Inc. (“Company”), a Delaware corporation, does hereby certify in such capacity and on behalf of the Company, pursuant to Section 7(m) of the Sales Agreement dated August 4, 2021 (the “Sales Agreement”) between the Company and ▇▇▇▇▇ and Company, LLC, that to the knowledge of the undersigned:

Officer Certificate. The undersigned, the duly qualified and elected _______________________, of OtonomyTenax Therapeutics, Inc. (“Company”), a Delaware corporation, does hereby certify in such capacity and on behalf of the Company, pursuant to Section 7(m) of the Sales Agreement dated August 4February 23, 2021 2015 (the “Sales Agreement”) between the Company and ▇▇▇▇▇ and Company, LLC, that to the best of the knowledge of the undersigned:.

Officer Certificate. The undersigned, the duly qualified and elected _______________________, of OtonomyAspen Aerogels, Inc. (“Company”), a Delaware corporation, does hereby certify in such capacity and on behalf of the Company, pursuant to Section 7(m) of the Sales Agreement dated August 4March 16, 2021 2022 (the “Sales Agreement”) between the Company and Company, ▇▇▇▇▇ and Company, LLCLLC and ▇▇▇▇▇ ▇▇▇▇▇▇▇ & Co., that to the best of the knowledge of the undersigned:.

Officer Certificate. The undersigned, the duly qualified and elected _______________________, of OtonomyAvidity Biosciences, Inc. (“Company”), a Delaware corporation, does hereby certify in such capacity and on behalf of the Company, pursuant to Section 7(m) of the Sales Agreement dated August 4July 2, 2021 (the “Sales Agreement”) between the Company and ▇▇▇▇▇ and Company, LLC, that to the best of the knowledge of the undersigned:.

Officer Certificate. The undersigned, the duly qualified and elected _______________________, of Otonomy▇▇▇▇▇▇▇▇ Pharmaceuticals, Inc. (“Company”), a Delaware corporation, does hereby certify in such capacity and on behalf of the Company, pursuant to Section 7(m) of the Sales Agreement dated August 4November 5, 2021 2020 (the “Sales Agreement”) between the Company and ▇▇▇▇▇ and Company, LLC, that to the best of the knowledge of the undersigned:.

Officer Certificate. The undersigned, the duly qualified and elected appointed _______________________, of Otonomy, Ultragenyx Pharmaceutical Inc. (“Company”), a Delaware corporation, does hereby certify in such capacity and on behalf of the Company, pursuant to Section 7(m) of the Sales Agreement dated August 4July 31, 2021 2017 (the “Sales Agreement”) between the Company and ▇▇▇▇▇ and Company, LLC, that to the knowledge of the undersigned:.

Officer Certificate. The undersigned, the duly qualified and elected ________________________ of PURE Bioscience, of OtonomyInc., Inc. a Delaware corporation (the “Company”), a Delaware corporation, does hereby certify in such capacity and on behalf of the Company, pursuant to Section 7(m) of the Sales Agreement dated August 4April __, 2021 2011 (the “Sales Agreement”) between the Company and ▇. ▇. ▇▇▇▇▇▇ and & Company, LLCInc., that to the best of the knowledge of the undersigned:

Officer Certificate. The undersigned, the duly qualified and elected _______________________, of OtonomyCabaletta Bio, Inc. (“Company”), a Delaware corporation, does hereby certify in such capacity and on behalf of the Company, pursuant to Section 7(m) of the Sales Agreement dated August 4March 16, 2021 2023 (the “Sales Agreement”) between the Company and ▇▇▇▇▇ and Company, LLC, that to the best of the knowledge of the undersigned:.

Officer Certificate. The undersigned, the duly qualified and elected _______________________, of Otonomy▇▇▇▇▇▇▇▇ Pharmaceuticals, Inc. (“Company”), a Delaware corporation, does hereby certify in such capacity and on behalf of the Company, pursuant to Section 7(m) of the Sales Agreement dated August 4May 7, 2021 2024 (the “Sales Agreement”) between the Company and ▇▇▇▇▇ and Company, TD Securities (USA) LLC, that to the best of the knowledge of the undersigned:.

Officer Certificate. The undersigned, the duly qualified and elected _______________________, of OtonomyPassage Bio, Inc. (“Company”), a Delaware corporation, does hereby certify in such capacity and on behalf of the Company, pursuant to Section 7(m) of the Sales Agreement dated August 4March [__], 2021 (the “Sales Agreement”) between the Company and ▇C▇▇▇▇ and Company, LLC, that to the best of the knowledge of the undersigned:.

Officer Certificate. The undersigned, the duly qualified and elected _______________________, of OtonomyAlphatec Holdings, Inc. Inc., a Delaware corporation (“Company”), a Delaware corporation, does hereby certify in such capacity and on behalf of the Company, pursuant to Section 7(m) of the Sales Agreement dated August 46, 2021 2020 (the “Sales Agreement”) between the Company and ▇C▇▇▇▇ and Company, LLC, that to the knowledge of the undersigned:.

Officer Certificate. The undersigned, the duly qualified and elected _______________________, of OtonomyiTeos Therapeutics, Inc. (“Company”), a Delaware corporation, does hereby certify in such capacity (and not in any personal capacity) and on behalf of the Company, pursuant to Section 7(m) of the Sales Agreement dated August 4May 10, 2021 2023 (the “Sales Agreement”) between the Company and ▇▇▇▇▇ and Company, LLC, that to the best of the knowledge of the undersigned:.

Officer Certificate. The undersigned, the duly qualified and elected _______________________, of OtonomySana Biotechnology, Inc. (“Company”), a Delaware corporation, does hereby certify in such capacity and on behalf of the Company, pursuant to Section 7(m) of the Sales Agreement dated August 4May 8, 2021 2025 (the “Sales Agreement”) ), between the Company and ▇▇▇▇▇ and Company, TD Securities (USA) LLC, that to the best of the knowledge of the undersigned:

Officer Certificate. The undersigned, the duly qualified and elected _______________________, of OtonomySELLAS Life Sciences Group, Inc. (“Company”), a Delaware corporation, does hereby certify in such capacity and on behalf of the Company, pursuant to Section 7(m) of the Sales Agreement dated August 4March 20, 2021 2026 (the “Sales Agreement”) between the Company and ▇▇▇▇▇ and Company, TD Securities (USA) LLC, that to the best of the knowledge of the undersigned:.

Officer Certificate. The undersigned, the duly qualified and elected _______________________, of OtonomyAtara Biotherapeutics, Inc. (“Company”), a Delaware corporation, does hereby certify in such capacity and on behalf of the Company, pursuant to Section 7(m) of the Sales Agreement dated August 4February 26, 2021 2019 (the “Sales Agreement”) between the Company and ▇C▇▇▇▇ and Company, LLC, that to the best of the knowledge of the undersigned:.

Officer Certificate. The undersigned, the duly qualified and elected _______________________[ ], of OtonomySCYNEXIS, Inc. (“Company”), a Delaware corporation, does hereby certify in such capacity and on behalf of the Company, pursuant to Section 7(m) of the Sales Agreement dated August 4[ ], 2021 2016 (the “Sales Agreement”) between the Company and Cantor ▇▇▇▇▇▇▇▇▇▇ and Company, LLC& Co., that to the best of the knowledge of the undersigned:.

Officer Certificate. The undersigned, the duly qualified and elected _______________________, of OtonomyEos Energy Enterprises, Inc. (“Company”), a Delaware corporation, does hereby certify in such capacity and on behalf of the Company, pursuant to Section 7(m) of the Sales Agreement dated August 45, 2021 2022 (the “Sales Agreement”) between the Company and ▇▇▇▇▇ and Company, LLC, that to the best of the knowledge of the undersigned:.

Officer Certificate. The undersigned, the duly qualified and elected _______________________, of OtonomyGENERATION BIO CO., Inc. a Delaware corporation (the “Company”), a Delaware corporation, does hereby certify in such capacity and on behalf of the Company, pursuant to Section 7(m) of the Sales Agreement dated August 411, 2021 (the “Sales Agreement”) between the Company and ▇▇▇▇▇ and Company, LLC, that to the best of the knowledge of the undersigned:.

Officer Certificate. The undersigned, the duly qualified and elected _______________________, of Otonomy, Inc. (“Company”), a Delaware corporation, does hereby certify in such capacity and on behalf of the Company, pursuant to Section 7(m) of the Sales Agreement dated August 41, 2021 2019 (the “Sales Agreement”) between the Company and ▇▇▇▇▇ and Company, LLC, that to the knowledge of the undersigned:

Officer Certificate. The undersigned, the duly qualified and elected _______________________, of OtonomyTerns Pharmaceuticals, Inc. (“Company”), a Delaware corporation, does hereby certify in such capacity and on behalf of the Company, pursuant to Section 7(m) of the Sales Agreement dated August 4March 8, 2021 2022 (the “Sales Agreement”) between the Company and ▇▇▇▇▇ and Company, LLC, that to the best of the knowledge of the undersigned:.

Officer Certificate. The undersigned, the duly qualified and elected _______________________, of OtonomyMacroGenics, Inc. Inc., a Delaware corporation (“Company”), a Delaware corporation, does hereby certify in such capacity and on behalf of the Company, pursuant to Section 7(m) of the Sales Agreement dated August November 4, 2021 2020 (the “Sales Agreement”) between the Company and ▇▇▇▇▇ and Company, LLC, that to the best of the knowledge of the undersigned:

Officer Certificate. The undersigned, the duly qualified and elected _______________________, of Otonomy▇▇▇▇▇ Therapeutics, Inc. (“Company”), a Delaware corporation, does hereby certify in such capacity and on behalf of the Company, pursuant to Section 7(m) of the Sales Agreement dated August 4June 5, 2021 2025 (the “Sales Agreement”) between the Company and ▇▇▇▇▇ and Company, TD Securities (USA) LLC, that to the knowledge of the undersigned:.

Officer Certificate. The undersigned, the duly qualified and elected _______________________, of Otonomy▇▇▇▇▇▇▇ Biotech, Inc. Inc., a Delaware corporation, (“Company”), a Delaware corporation, does hereby certify in such capacity and on behalf of the Company, pursuant to Section 7(m) of the Sales Agreement Agreement, dated August 4December 31, 2021 2020 (the “Sales Agreement”) between the Company and ▇▇▇▇▇ and Company, LLC, that to the best of the knowledge of the undersigned:.

Officer Certificate. The undersigned, the duly qualified and elected _______________________, of OtonomyProteon Therapeutics, Inc. (“Company”), a Delaware corporation, does hereby certify in such capacity and on behalf of the Company, pursuant to Section 7(m) of the Sales Agreement dated August 4November 12, 2021 2015 (the “Sales Agreement”) between the Company and ▇▇▇▇▇ and Company, LLC, that to the best of the knowledge of the undersigned:

Officer Certificate. The undersigned, the duly qualified and elected _______________________, of OtonomyAnnexon, Inc. Inc., a Delaware corporation (“Company”), a Delaware corporation, does hereby certify in such capacity and on behalf of the Company, pursuant to Section 7(m) of the Sales Agreement dated August 416, 2021 (the “Sales Agreement”) between the Company and ▇▇▇▇▇ and Company, LLC, that to the best of the knowledge of the undersigned:.

Officer Certificate. The undersigned, the duly qualified and elected _______________________, of OtonomyArcutis Biotherapeutics, Inc. (“Company”), a Delaware corporation, does hereby certify in such capacity and on behalf of the Company, pursuant to Section 7(m) of the Amended and Restated Sales Agreement dated August 4January 31, 2021 2024 (the “Sales Agreement”) between the Company and ▇▇▇▇▇ and Company, LLC, that to the best of the knowledge of the undersigned:.

Officer Certificate. The undersigned, the duly qualified and elected _______________________, of OtonomyCoherus BioSciences, Inc. (“Company”), a Delaware corporation, does hereby certify in such capacity and on behalf of the Company, pursuant to Section 7(m) of the Sales Agreement dated August 4November 8, 2021 2022 (the “Sales Agreement”) between the Company and ▇C▇▇▇▇ and Company, LLC, that to the best of the knowledge of the undersigned:.

Officer Certificate. The undersigned, the duly qualified and elected appointed _______________________, of OtonomyAadi Bioscience, Inc. (“Company”), a Delaware corporation, does hereby certify in such capacity and on behalf of the Company, pursuant to Section 7(m) of the Sales Agreement dated August 4March 17, 2021 2022 (the “Sales Agreement”) between the Company and ▇▇▇▇▇ and Company, LLC, that to the best of the knowledge of the undersigned:.

Officer Certificate. The undersigned, the duly qualified and elected ________________________ , of Otonomy▇▇▇▇▇ TECHNOLOGIES, Inc. INC. (“"Company”"), a Delaware corporation, does hereby certify in such capacity and on behalf of the Company, pursuant to Section 7(m) of the Sales Agreement dated August 4April 7, 2021 2010 (the “"Sales Agreement”") between the Company and Cantor ▇▇▇▇▇▇▇▇▇▇ and Company, LLC& Co., that to the best of the knowledge of the undersigned:.

Officer Certificate. The undersigned, the duly qualified and elected _______________________, of OtonomyMacroGenics, Inc. (“Company”), a Delaware corporation, does hereby certify in such capacity and on behalf of the Company, pursuant to Section 7(m) of the Sales Agreement dated August 4, 2021 2017 (the “Sales Agreement”) between the Company and ▇▇▇▇▇ and Company, LLC, that to the knowledge of the undersigned:.

Officer Certificate. The undersigned, the duly qualified and elected _______________________, of OtonomyClearside Biomedical, Inc. (“Company”), a Delaware corporation, does hereby certify in such capacity and on behalf of the Company, pursuant to Section 7(m) of the Sales Agreement dated August 4June 30, 2021 2017 (the “Sales Agreement”) between the Company and ▇▇▇▇▇ and Company, LLC, that to the best of the knowledge of the undersigned:.

Officer Certificate. The undersigned, the duly qualified and elected _______________________, of OtonomyAlimera Sciences, Inc. (“Company”), a Delaware corporation, does hereby certify in such capacity and on behalf of the Company, pursuant to Section 7(m) of the Sales Agreement dated August 4October 20, 2021 2017 (the “Sales Agreement”) between the Company and ▇.▇. ▇▇▇▇▇▇▇▇▇▇ and Company& Co., LLC, that to the best of the knowledge of the undersigned:

Officer Certificate. The undersigned, the duly qualified and elected _______________________, _ of Otonomy, Inc. Nektar Therapeutics (the “Company”), a Delaware corporation, does hereby certify in such capacity and on behalf of the Company, pursuant to Section 7(m) of the Sales Agreement dated August 4March 12, 2021 (the “Sales Agreement”) between the Company and ▇▇▇▇▇ and Company, LLC, that to the best of the knowledge of the undersigned:.

Officer Certificate. The undersigned, the duly qualified and elected appointed _______________________, of OtonomyAppHarvest, Inc. Inc., a Delaware public benefit corporation (the “Company”), a Delaware corporation, does hereby certify in such capacity and on behalf of the Company, pursuant to Section 7(m) of the Sales Agreement dated August 43, 2021 2022 (the “Sales Agreement”) between the Company and ▇▇▇▇▇ and Company, LLC, that to the best of the knowledge of the undersigned:

Officer Certificate. The undersigned, the duly qualified and elected _______________________, of Otonomy, Inc. Absci Corporation (“Company”), a Delaware corporation, does hereby certify in such capacity and on behalf of the Company, pursuant to Section 7(m) of the Sales Agreement dated August 412, 2021 2025 (the “Sales Agreement”) between the Company and ▇▇▇▇▇ and Company, TD Securities (USA) LLC, that to the best of the knowledge of the undersigned:.

Officer Certificate. The undersigned, the duly qualified and elected _______________________, of Otonomy▇▇▇▇▇▇ Pharmaceuticals, Inc. (“Company”), a Delaware corporation, does hereby certify in such capacity and on behalf of the Company, pursuant to Section 7(m) of the Sales Agreement dated August 4December 3, 2021 2018 (the “Sales Agreement”) between the Company and ▇▇▇▇▇ and Company, LLC, that to the knowledge of the undersigned:

Officer Certificate. The undersigned, the duly qualified and elected _______________________, of OtonomyCorindus Vascular Robotics, Inc. (“Company”), a Delaware corporation, does hereby certify in such capacity and on behalf of the Company, pursuant to Section 7(m) of the Sales Agreement dated August 431, 2021 2018 (the “Sales Agreement”) between the Company and ▇C▇▇▇▇ and Company, LLC, that to the best of the knowledge of the undersigned:.

Officer Certificate. The undersigned, the duly qualified and elected _______________________, of OtonomyMolecular Templates, Inc. (the “Company”), a Delaware corporation, does hereby certify in such capacity and on behalf of the Company, pursuant to Section 7(m) of the Sales Agreement dated August 47, 2021 2020 (the “Sales Agreement”) between the Company and ▇▇▇▇▇ and Company, LLC, that to the best of the knowledge of the undersigned:.

Officer Certificate. The undersigned, the duly qualified and elected _______________________, of OtonomyThreshold Pharmaceuticals, Inc. Inc., a Delaware corporation (the “Company”), a Delaware corporation, does hereby certify in such capacity and on behalf of the Company, pursuant to Section 7(m) of the Sales Agreement dated August 4November 2, 2021 2015 (the “Sales Agreement”) between the Company and ▇▇▇▇▇ and Company, LLC, that to the best of the knowledge of the undersigned:.

Officer Certificate. The undersigned, the duly qualified and elected _______________________, of OtonomyFive Prime Therapeutics, Inc. (“Company”), a Delaware corporation, does hereby certify in such capacity and on behalf of the Company, pursuant to Section 7(m) of the Sales Agreement dated August 46, 2021 2020 (the “Sales Agreement”) between the Company and ▇▇▇▇▇ and Company, LLC, that to the best of the knowledge of the undersigned:.

Officer Certificate. The undersigned, the duly qualified and elected _______________________, of OtonomyProPhase Labs, Inc. (“Company”), a Delaware corporation, does hereby certify in such capacity and on behalf of the Company, pursuant to Section 7(m) of the Sales Agreement dated August 4October 9, 2021 2025 (the “Sales Agreement”) between the Company and ▇▇▇▇▇ and CompanyWestPark Capital, LLCInc., that to the best of the knowledge of the undersigned:

Officer Certificate. The undersigned, the duly qualified and elected appointed _______________________, of OtonomySana Biotechnology, Inc. (“Company”), a Delaware corporation, does hereby certify in such capacity and on behalf of the Company, pursuant to Section 7(m) of the Amended and Restated Sales Agreement dated August 4March 3, 2021 2026 (the “Sales Agreement”) ), between the Company and ▇▇▇▇▇ and Company, TD Securities (USA) LLC, that to the best of the knowledge of the undersigned:

Officer Certificate. The undersigned, the duly qualified and elected _______________________, of OtonomyUnity Biotechnology, Inc. (“Company”), a Delaware corporation, does hereby certify in such capacity and in no other capacity, on behalf of the Company, pursuant to Section 7(m) of the Sales Agreement dated August 4, 2021 2020 (the “Sales Agreement”) between the Company and ▇▇▇▇▇ and Company, LLC, that to the best of the knowledge of the undersigned:.

Officer Certificate. The undersigned, the duly qualified and elected _______________________, of OtonomyAdamas Pharmaceuticals, Inc. (“Company”), a Delaware corporation, does hereby certify in such capacity and on behalf of the Company, pursuant to Section 7(m) of the Sales Agreement dated August 4November 7, 2021 2019 (the “Sales Agreement”) between the Company and ▇▇▇▇▇ and Company, LLC, that to the best of the knowledge of the undersigned:.

Officer Certificate. The undersigned, the duly qualified and elected _______________________, of OtonomyMolecular Templates, Inc. (the “Company”), a Delaware corporation, does hereby certify in such capacity and on behalf of the Company, pursuant to Section 7(m) of the Sales Agreement dated August 47, 2021 2020 (the “Sales Agreement”) between the Company and ▇C▇▇▇▇ and Company, LLC, that to the best of the knowledge of the undersigned:.

Officer Certificate. The undersigned, the duly qualified and elected _______________________, of OtonomyRevance Therapeutics, Inc. (“Company”), a Delaware corporation, does hereby certify in such capacity and on behalf of the Company, pursuant to Section 7(m) of the Sales Agreement dated August 4May 10, 2021 2022 (the “Sales Agreement”) between the Company and ▇▇▇▇▇ and Company, LLC, that to the best of the knowledge of the undersigned:

Officer Certificate. The undersigned, the duly qualified and elected _______________________, of Otonomy▇▇▇▇▇▇▇, Inc. (“Company”), a Delaware corporation, does hereby certify in such capacity and on behalf of the Company, pursuant to Section 7(m) of the Sales Agreement dated August 4February 3, 2021 2016 (the “Sales Agreement”) between the Company and ▇▇▇▇▇ and Company, LLC, that to the best of the knowledge of the undersigned:.

Officer Certificate. The undersigned, the duly qualified and elected _______________________, of OtonomyG1 Therapeutics, Inc. (“Company”), a Delaware corporation, does hereby certify in such capacity and on behalf of the Company, pursuant to Section 7(m) of the Sales Agreement dated August 4, 2021 2018 (the “Sales Agreement”) between the Company and ▇▇▇▇▇ and Company, LLC, that to the best of the knowledge of the undersigned:.

Officer Certificate. The undersigned, the duly qualified and elected _______________________, of OtonomyAdverum Biotechnologies, Inc. (“Company”), a Delaware corporation, does hereby certify in such capacity and on behalf of the Company, pursuant to Section 7(m) of the Sales Agreement dated August 4May 11, 2021 2023 (the “Sales Agreement”) between the Company and ▇▇▇▇▇ and Company, LLC, that to the knowledge of the undersigned:

Officer Certificate. The undersigned, the duly qualified and elected _______________________, of OtonomyAtara Biotherapeutics, Inc. (“Company”), a Delaware corporation, does hereby certify in such capacity and on behalf of the Company, pursuant to Section 7(m8(m) of the Sales Agreement dated August 4November 1, 2021 2023 (the “Sales Agreement”) between the Company and ▇▇▇▇▇ and Company, LLC, that to the best of the knowledge of the undersigned:.

Officer Certificate. The undersigned, the duly qualified and elected _______________________, of OtonomyMacroGenics, Inc. Inc., a Delaware corporation (“Company”), a Delaware corporation, does hereby certify in such capacity and on behalf of the Company, pursuant to Section 7(m) of the Sales Agreement dated August 4March 15, 2021 2023 (the “Sales Agreement”) between the Company and ▇C▇▇▇▇ and Company, LLC, that to the best of the knowledge of the undersigned:

Officer Certificate. The undersigned, the duly qualified and elected _______________________, of OtonomyMacroGenics, Inc. (“Company”), a Delaware corporation, does hereby certify in such capacity and on behalf of the Company, pursuant to Section 7(m) of the Sales Agreement dated August 4, 2021 2019 (the “Sales Agreement”) between the Company and ▇▇▇▇▇ and Company, LLC, that to the knowledge of the undersigned:.

Officer Certificate. The undersigned, the duly qualified and elected _______________________, of OtonomySage Therapeutics, Inc. (“Company”), a Delaware corporation, does hereby certify in such capacity and on behalf of the Company, pursuant to Section 7(m) of the Sales Agreement dated August 4, 2021 2023 (the “Sales Agreement”) between the Company and ▇▇▇▇▇ and Company, LLC, that to the best of the knowledge of the undersigned:.

Officer Certificate. The undersigned, the duly qualified and elected _______________________, of OtonomyHTG Molecular Diagnostics, Inc. (“Company”), a Delaware corporation, does hereby certify in such capacity and on behalf of the Company, pursuant to Section 7(m) of the Sales Agreement dated August 4March 13, 2021 2019 (the “Sales Agreement”) between the Company and ▇▇▇▇▇ and Company, LLC, that to the best of the knowledge of the undersigned:.

Officer Certificate. The undersigned, the duly qualified and elected _______________________, of OtonomySera Prognostics, Inc. (the “Company”), a Delaware corporation, does hereby certify in such capacity and on behalf of the Company, pursuant to Section 7(m) of the Sales Agreement dated August 4[•], 2021 2024 (the “Sales Agreement”) between the Company and ▇▇▇▇▇ and Company, TD Securities (USA) LLC, that to the best of the knowledge of the undersigned:.

Officer Certificate. The undersigned, the duly qualified and elected _______________________, of OtonomyTerns Pharmaceuticals, Inc. (“Company”), a Delaware corporation, does hereby certify in such capacity and on behalf of the CompanyCompany (and not in such officer’s individual capacity), pursuant to Section 7(m) of the Sales Agreement dated August 4[], 2021 2023 (the “Sales Agreement”) between the Company and ▇▇▇▇▇ and Company, LLC, that to the best of the knowledge of the undersigned:.

Officer Certificate. The undersigned, the duly qualified and elected _______________________, of OtonomyArcutis Biotherapeutics, Inc. (“Company”), a Delaware corporation, does hereby certify in such capacity and on behalf of the Company, pursuant to Section 7(m) of the Sales Agreement dated August 4May 6, 2021 (the “Sales Agreement”) between the Company and ▇▇▇▇▇ and Company, LLC, that to the best of the knowledge of the undersigned:.

Officer Certificate. The undersigned, the duly qualified and elected _______________________, of OtonomyAlpine Immune Sciences, Inc. (“Company”), a Delaware corporation, does hereby certify in such capacity and on behalf of the Company, pursuant to Section 7(m) of the Sales Agreement dated August 4July 2, 2021 (the “Sales Agreement”) between the Company and ▇▇▇▇▇ and Company, LLC, that to the knowledge of the undersigned:.

Officer Certificate. The undersigned, the duly qualified and elected _______________________, of Otonomy▇▇▇▇▇▇▇ Biotech, Inc. Inc., a Delaware corporation, (“Company”), a Delaware corporation, does hereby certify in such capacity and on behalf of the Company, pursuant to Section 7(m) of the Sales Agreement Agreement, dated August 4May 8, 2021 2023 (the “Sales Agreement”) between the Company and ▇▇▇▇▇ and Company, LLC, that to the best of the knowledge of the undersigned:.

Officer Certificate. The undersigned, the duly qualified and elected _______________________, of OtonomyJounce Therapeutics, Inc. (“Company”), a Delaware corporation, does hereby certify in such capacity and on behalf of the Company, pursuant to Section 7(m) of the Sales Agreement dated August November 4, 2021 (the “Sales Agreement”) between the Company and ▇▇▇▇▇ and Company, LLC, that to the best of the knowledge of the undersigned:.

Officer Certificate. The undersigned, the duly qualified and elected _______________________, of OtonomyCabaletta Bio, Inc. (“Company”), a Delaware corporation, does hereby certify in such capacity and on behalf of the Company, pursuant to Section 7(m) of the Sales Agreement dated August 47, 2021 2025 (the “Sales Agreement”) between the Company and ▇▇▇▇▇ and Company, TD Securities (USA) LLC, that to the best of the knowledge of the undersigned:.

Officer Certificate. The undersigned, the duly qualified and elected _______________________, of OtonomyAduro Biotech, Inc. (“Company”), a Delaware corporation, does hereby certify in such capacity and on behalf of the Company, pursuant to Section 7(m) of the Sales Agreement dated August 4May 2, 2021 2016 (the “Sales Agreement”) between the Company and ▇C▇▇▇▇ and Company, LLC, that to the best of the knowledge of the undersigned:

Officer Certificate. The undersigned, the duly qualified and elected _______________________, of OtonomyCytori Therapeutics, Inc. (“Company”), a Delaware corporation, does hereby certify in such capacity and on behalf of the Company, pursuant to Section 7(m) of the Sales Agreement dated August 4June , 2021 2018 (the “Sales Agreement”) between the Company and ▇. ▇▇▇▇▇ and CompanyFBR, LLCInc., that to the knowledge of the undersigned:.

Officer Certificate. The undersigned, the duly qualified and elected _______________________, of OtonomyTyra Biosciences, Inc. Inc., a Delaware corporation (the “Company”), a Delaware corporation, does hereby certify in such capacity and on behalf of the Company, pursuant to Section 7(m7(o) of the Sales Agreement dated August 4May 8, 2021 2025 (the “Sales Agreement”) between the Company and ▇▇▇▇▇ and Company, TD Securities (USA) LLC, that to the best of the knowledge of the undersigned:.

Officer Certificate. The undersigned, the duly qualified and elected _______________________, of OtonomyBionano Genomics, Inc. (“Company”), a Delaware corporation, does hereby certify in such capacity and on behalf of the Company, pursuant to Section 7(m) of the Sales Agreement dated August 4March , 2021 (the “Sales Agreement”) between the Company and ▇▇▇▇▇ and Company, LLC, that to the best of the knowledge of the undersigned:.

Officer Certificate. The undersigned, the duly qualified and elected _______________________, of Otonomy▇▇▇▇▇▇ Pharmaceuticals, Inc. (“Company”), a Delaware corporation, does hereby certify in such capacity and on behalf of the Company, pursuant to Section 7(m8(m) of the At Market Issuance Sales Agreement dated August 4December 23, 2021 (the “Sales Agreement”) between the Company and ▇. ▇▇▇▇▇ and CompanySecurities, LLCInc., that to the knowledge of the undersigned:

Officer Certificate. The undersigned, the duly qualified and elected _______________________, of OtonomyGalecto, Inc. (“Company”), a Delaware corporation, does hereby certify in such capacity and on behalf of the Company, pursuant to Section 7(m) of the Sales Agreement dated August 4February 10, 2021 2026 (the “Sales Agreement”) between the Company and ▇▇▇▇▇ and Company, TD Securities (USA) LLC, that to the knowledge of the undersigned:

Officer Certificate. The undersigned, the duly qualified and elected _______________________, of OtonomyBolt Biotherapeutics, Inc. (“Company”), a Delaware corporation, does hereby certify in such capacity and on behalf of the Company, pursuant to Section 7(m) of the Sales Agreement dated August 4March 30, 2021 2022 (the “Sales Agreement”) between the Company and ▇▇▇▇▇ and Company, LLC, that to the best of the knowledge of the undersigned:.

Officer Certificate. The undersigned, the duly qualified and elected _______________________, of Otonomy, Capricor Therapeutics Inc. (“Company”), a Delaware corporation, does hereby certify in such capacity and on behalf of the Company, pursuant to Section 7(m) of the Sales Agreement dated August 4October 19, 2021 2017 (the “Sales Agreement”) between the Company and H.▇. ▇▇▇▇▇▇▇▇▇▇ and Company& Co., LLC, that to the best of the knowledge of the undersigned:

Officer Certificate. The undersigned, the duly qualified and elected _______________________, of OtonomyAtara Biotherapeutics, Inc. (“Company”), a Delaware corporation, does hereby certify in such capacity and on behalf of the Company, pursuant to Section 7(m) of the Sales Agreement dated August 4November 26, 2021 (the “Sales Agreement”) between the Company and ▇▇▇▇▇ and Company, LLC, that to the best of the knowledge of the undersigned:.

Officer Certificate. The undersigned, the duly qualified and elected _______________________, of OtonomyAVITA Medical, Inc. (“Company”), a Delaware corporation, does hereby certify in such capacity and on behalf of the Company, pursuant to Section 7(m) of the Sales Agreement dated August 4April 14, 2021 2023 (the “Sales Agreement”) between the Company and ▇▇▇▇▇ and Company, LLC, that to the knowledge of the undersigned:

Officer Certificate. The undersigned, the duly qualified and elected _______________________, of OtonomyAlimera Sciences, Inc. (“Company”), a Delaware corporation, does hereby certify in such capacity and on behalf of the Company, pursuant to Section 7(m) of the Sales Agreement dated August 4. , 2021 2014 (the “Sales Agreement”) between the Company and ▇▇▇▇▇ and Company, LLC, that to the knowledge of the undersigned:

Officer Certificate. The undersigned, the duly qualified and elected _______________________, of Otonomy, Inc. Twist Bioscience Corporation (“Company”), a Delaware corporation, does hereby certify in such capacity and on behalf of the Company, pursuant to Section 7(m) of the Sales Agreement dated August 4December 18, 2021 2019 (the “Sales Agreement”) between the Company and ▇▇▇▇▇ and Company, LLC, that to the best of the knowledge of the undersigned:.

Officer Certificate. The undersigned, the duly qualified and elected _______________________, of OtonomyC4 Therapeutics, Inc. (“Company”), a Delaware corporation, does hereby certify in such capacity and on behalf of the Company, pursuant to Section 7(m) of the Sales Agreement dated August 4November 10, 2021 (the “Sales Agreement”) between the Company and ▇▇▇▇▇ and Company, LLC, that to the best of the knowledge of the undersigned:.

Officer Certificate. The undersigned, the duly qualified and elected _______________________, of OtonomyNuvalent, Inc. (“Company”), a Delaware corporation, does hereby certify in such capacity and on behalf of the Company, pursuant to Section 7(m) of the Sales Agreement dated August 4, 2021 2022 (the “Sales Agreement”) between the Company and ▇▇▇▇▇ and Company, LLC, that to the best of the knowledge of the undersigned:.

Officer Certificate. The undersigned, the duly qualified and elected _______________________, of OtonomyUnity Biotechnology, Inc. (“Company”), a Delaware corporation, does hereby certify in such capacity and in no other capacity, on behalf of the Company, pursuant to Section 7(m) of the Sales Agreement dated August 4, 2021 2022 (the “Sales Agreement”) between the Company and ▇C▇▇▇▇ and Company, LLC, that to the best of the knowledge of the undersigned:.

Officer Certificate. The undersigned, the duly qualified and elected appointed ________________________ of ▇▇▇▇▇▇.▇▇ Inc., of Otonomy, Inc. a Delaware Corporation (the “Company”), a Delaware corporation, does hereby certify in such capacity and on behalf of the Company, pursuant to Section 7(m) of the Sales Agreement Agreement, dated August 4July [●], 2021 2025 (the “Sales Agreement”) ), between the Company and ▇▇▇▇▇ and CompanyA.G.P./Alliance Global Partners, LLC, that to the knowledge of the undersignedthat:

Officer Certificate. The undersigned, the duly qualified and elected _______________________, of OtonomyCaladrius Biosciences, Inc. (“Company”), a Delaware corporation, does hereby certify in such capacity and on behalf of the Company, pursuant to Section 7(m) of the Sales Agreement dated August 4February 8, 2021 2018 (the “Sales Agreement”) between the Company and ▇.▇. ▇▇▇▇▇▇▇▇▇▇ and Company& Co., LLC, that to the best of the knowledge of the undersigned:

Officer Certificate. The undersigned, the duly qualified and elected _______________________, of Otonomy, Inc. Fluidigm Corporation (the “Company”), a Delaware corporation, does hereby certify in such capacity and on behalf of the Company, pursuant to Section 7(m) of the Sales Agreement dated August 43, 2021 2017 (the “Sales Agreement”) between the Company and ▇▇▇▇▇ and Company, LLC, that to the knowledge of the undersigned:

Officer Certificate. The undersigned, the duly qualified and elected _______________________, of OtonomySutro Biopharma, Inc. (“Company”), a Delaware corporation, does hereby certify in such capacity and on behalf of the Company, pursuant to Section 7(m) of the Sales Agreement dated August October 4, 2021 2019 (the “Sales Agreement”) between the Company and ▇▇▇▇▇ and Company, LLC, that to the best of the knowledge of the undersigned:.

Officer Certificate. The undersigned, the duly qualified and elected _______________________, of OtonomySyndax Pharmaceuticals, Inc. (“Company”), a Delaware corporation, does hereby certify in such capacity and on behalf of the Company, pursuant to Section 7(m) of the Sales Agreement dated August 4May 26, 2021 2023 (the “Sales Agreement”) between the Company and ▇▇▇▇▇ and Company, LLC, that to the best of the knowledge of the undersigned:.

Officer Certificate. The undersigned, the duly qualified and elected _______________________, of Otonomy▇▇▇▇ Therapeutics, Inc. (“Company”), a Delaware corporation, does hereby certify in such capacity and on behalf of the Company, pursuant to Section 7(m) of the Sales Agreement dated August 45, 2021 2025 (the “Sales Agreement”) between the Company and ▇▇▇▇▇ and Company, TD Securities (USA) LLC, that to the best of the knowledge of the undersigned:

Officer Certificate. The undersigned, the duly qualified and elected _______________________, of OtonomyTricida, Inc. (“Company”), a Delaware corporation, does hereby certify in such capacity and on behalf of the Company, pursuant to Section 7(m) of the Sales Agreement dated August 4dated, [__], 2021 (the “Sales Agreement”) between the Company and ▇▇▇▇▇ and Company, LLC, that to the best of the knowledge of the undersigned:.

Officer Certificate. The undersigned, the duly qualified and elected _______________________, of Otonomy▇▇▇▇▇▇ Pharmaceuticals, Inc. (“Company”), a Delaware corporation, does hereby certify in such capacity and on behalf of the Company, pursuant to Section 7(m8(m) of the At Market Issuance Sales Agreement dated August 4March 29, 2021 (the “Sales Agreement”) between the Company and ▇. ▇▇▇▇▇ and CompanySecurities, LLCInc., that to the knowledge of the undersigned:

Officer Certificate. The undersigned, the duly qualified and elected _______________________, of OtonomyViveve Medical, Inc. (“Company”), a Delaware corporation, does hereby certify in such capacity and on behalf of the Company, pursuant to Section 7(m) of the Sales Agreement dated August 4, 2021 2017 (the “Sales Agreement”) between the Company and ▇▇▇▇▇ and Company, LLC, that to the best of the knowledge of the undersigned:.

Officer Certificate. The undersigned, the duly qualified and elected _______________________, of OtonomySurrozen, Inc. Inc., a Delaware corporation (“Company”), a Delaware corporation, does hereby certify in such capacity and on behalf of the Company, pursuant to Section 7(m) of the Sales Agreement dated August 4March 23, 2021 2026 (the “Sales Agreement”) between the Company and ▇▇▇▇▇ and Company, TD Securities (USA) LLC, that to the best of the knowledge of the undersigned:

Officer Certificate. The undersigned, the duly qualified and elected _______________________, of OtonomyCabaletta Bio, Inc. (“Company”), a Delaware corporation, does hereby certify in such capacity and on behalf of the Company, pursuant to Section 7(m) of the Sales Agreement dated August 4March 21, 2021 2024 (the “Sales Agreement”) between the Company and ▇▇▇▇▇ and Company, LLC, that to the best of the knowledge of the undersigned:.

Officer Certificate. The undersigned, the duly qualified and elected _______________________, of OtonomyKalaris Therapeutics, Inc. (“Company”), a Delaware corporation, does hereby certify in such capacity and on behalf of the Company, pursuant to Section 7(m) of the Sales Agreement dated August 4April 3, 2021 2026 (the “Sales Agreement”) between the Company and ▇▇▇▇▇ and Company, TD Securities (USA) LLC, that to the best of the knowledge of the undersigned:.

Officer Certificate. The undersigned, the duly qualified and elected _______________________, of OtonomyRocket Pharmaceuticals, Inc. (“Company”), a Delaware corporation, does hereby certify in such capacity and on behalf of the Company, pursuant to Section 7(m) of the Sales Agreement dated August 4February 28, 2021 2022 (the “Sales Agreement”) between the Company and ▇▇▇▇▇ and Company, LLC, that to the best of the knowledge of the undersigned:.

Officer Certificate. The undersigned, the duly qualified and elected _______________________, of OtonomyIO Biotech, Inc. (“Company”), a Delaware corporation, does hereby certify in such capacity and on behalf of the Company, pursuant to Section 7(m) of the Sales Agreement dated August 4February 15, 2021 2023 (the “Sales Agreement”) between the Company and ▇▇▇▇▇ and Company, LLC, that to the best of the knowledge of the undersigned:.

Officer Certificate. The undersigned, the duly qualified and elected _______________________, of OtonomyNkarta, Inc. (“Company”), a Delaware corporation, does hereby certify in such capacity and on behalf of the Company, pursuant to Section 7(m) of the Sales Agreement dated August 412, 2021 (the “Sales Agreement”) between the Company and ▇▇▇▇▇ and Company, LLC, that to the best of the knowledge of the undersigned:.

Officer Certificate. The undersigned, the duly qualified and elected _______________________, of OtonomyJounce Therapeutics, Inc. (“Company”), a Delaware corporation, does hereby certify in such capacity and on behalf of the Company, pursuant to Section 7(m) of the Sales Agreement dated August 4December 17, 2021 2019 (the “Sales Agreement”) between the Company and ▇▇▇▇▇ and Company, LLC, that to the best of the knowledge of the undersigned:.

Officer Certificate. The undersigned, the duly qualified and elected _______________________, of OtonomyAmerican Apparel, Inc. (“Company”), a Delaware corporation, does hereby certify in such capacity and on behalf of the Company, pursuant to Section 7(m7(l) of the Sales Agreement dated August 4May 11, 2021 2015 (the “Sales Agreement”) between the Company and ▇▇▇▇▇ and Company, LLC, that to the best of the knowledge of the undersigned:.

Officer Certificate. The undersigned, the duly qualified and elected _______________________, of Otonomy, vTv Therapeutics Inc. (“Company”), a Delaware corporation, does hereby certify in such capacity and on behalf of the Company, pursuant to Section 7(m) of the Sales Agreement dated August 4February 28, 2021 2024 (the “Sales Agreement”) between the Company and ▇▇▇▇▇ and Company, LLC, that to the best of the knowledge of the undersigned:.

Officer Certificate. The undersigned, the duly qualified and elected _______________________, of OtonomyMorphic Holding, Inc. (“Company”), a Delaware corporation, does hereby certify in such capacity and on behalf of the Company, pursuant to Section 7(m) of the Sales Agreement dated August 4April 26, 2021 2024 (the “Sales Agreement”) between the Company and ▇▇▇▇▇ and Company, TD Securities (USA) LLC, that to the best of the knowledge of the undersigned:.

Officer Certificate. The undersigned, the duly qualified and elected _______________________, of Otonomy, Bicara Therapeutics Inc. (“Company”), a Delaware corporation, does hereby certify in such capacity and on behalf of the Company, pursuant to Section 7(m) of the Sales Agreement dated August 4October 3, 2021 2025 (the “Sales Agreement”) between the Company and ▇▇▇▇▇ and Company, TD Securities (USA) LLC, that to the best of the knowledge of the undersigned:.

Officer Certificate. The undersigned, the duly qualified and elected _______________________, of OtonomyDermTech, Inc. (“Company”), a Delaware corporation, does hereby certify in such capacity and on behalf of the Company, pursuant to Section 7(m) of the Sales Agreement dated August 4November 10, 2021 2020 (the “Sales Agreement”) between the Company and ▇▇▇▇▇ and Company, LLC, that to the best of the knowledge of the undersigned:

Officer Certificate. The undersigned, the duly qualified and elected _______________________, of OtonomyRapid Micro Biosystems, Inc. Inc., a Delaware corporation (the “Company”), a Delaware corporation, does hereby certify in such capacity and on behalf of the CompanyCompany (and not in the undersigned’s individual capacity), pursuant to Section 7(m) of the Sales Agreement dated August 4December 15, 2021 2023 (the “Sales Agreement”) ), by and between the Company and ▇▇▇▇▇ and Company, LLC, that to the best of the knowledge of the undersigned:.

Officer Certificate. The undersigned, the duly qualified and elected _______________________, of Otonomy, Allakos Inc. (“Company”), a Delaware corporation, does hereby certify in such capacity and on behalf of the Company, pursuant to Section 7(m) of the Sales Agreement dated August 4[•], 2021 (the “Sales Agreement”) between the Company and ▇C▇▇▇▇ and Company, LLC, that to the best of the knowledge of the undersigned:.

Officer Certificate. The undersigned, the duly qualified and elected _______________________, of OtonomyProtara Therapeutics, Inc. (“Company”), a Delaware corporation, does hereby certify in such capacity and on behalf of the Company, pursuant to Section 7(m) of the Sales Agreement dated August 4May 13, 2021 2026 (the “Sales Agreement”) between the Company and ▇▇▇▇▇ and Company, TD Securities (USA) LLC, that to the best of the knowledge of the undersigned:.