Common use of FORM OF SECRETARY’S CERTIFICATE Clause in Contracts

FORM OF SECRETARY’S CERTIFICATE. This Secretary’s Certificate (the “Certificate”) is being delivered pursuant to Section 7(k) of that certain Common Stock Purchase Agreement dated as of December __, 2019 (the “Common Stock Purchase Agreement”), by and between MIRAGEN THERAPEUTICS, INC., a Delaware corporation (the “Company”) and ASPIRE CAPITAL FUND, LLC, an Illinois limited liability company (the “Buyer”), pursuant to which the Company may sell to the Buyer up to Twenty Million Dollars ($20,000,000) of the Company’s Common Stock, par value $0.01 (the “Common Stock”). Terms used herein and not otherwise defined shall have the meanings ascribed to them in the Common Stock Purchase Agreement. The undersigned, _________________ Secretary of the Company, hereby certifies as follows in his capacity as such:

FORM OF SECRETARY’S CERTIFICATE. This Secretary’s Certificate (the “Certificate”) is being delivered pursuant to Section 7(k) of that certain Common Stock Purchase Agreement dated as of December __August 12, 2019 2014 (the “Common Stock Purchase Agreement”), by and between MIRAGEN THERAPEUTICSAPRICUS BIOSCIENCES, INC., a Delaware Nevada corporation (the “Company”) and ASPIRE CAPITAL FUND, LLC, an Illinois limited liability company (the “Buyer”), pursuant to which the Company may sell to the Buyer up to Twenty Twenty-Two Million Dollars ($20,000,00022,000,000) of the Company’s Common Stock, par value $0.01 0.001 (the “Common Stock”). Terms used herein and not otherwise defined shall have the meanings ascribed to them in the Common Stock Purchase Agreement. The undersigned, _________________ , Secretary of the Company, hereby certifies as follows in his capacity as such:

FORM OF SECRETARY’S CERTIFICATE. This Secretary’s Certificate (the “Certificate”) is being delivered pursuant to Section 7(k7(j) of that certain Common Stock Purchase Agreement dated as of December __March 16, 2019 2015 (the “Common Stock Purchase Agreement”), by and between MIRAGEN THERAPEUTICSBACTERIN INTERNATIONAL HOLDINGS, INC., a Delaware corporation (the “Company”) and ASPIRE CAPITAL FUND, LLC, an Illinois limited liability company (the “Buyer”), pursuant to which the Company may sell to the Buyer up to Twenty Ten Million Dollars ($20,000,00010,000,000) of the Company’s Common Stock, par value $0.01 0.000001 (the “Common Stock”). Terms used herein and not otherwise defined shall have the meanings ascribed to them in the Common Stock Purchase Agreement. The undersigned, _________________ , Secretary of the Company, hereby certifies as follows in his capacity as such, hereby certifies as follows:

FORM OF SECRETARY’S CERTIFICATE. This Secretary’s Certificate (the “Certificate”) is being delivered pursuant to Section 7(k) of that certain Common Stock Purchase Agreement dated as of December __July 24, 2019 2015 (the “Common Stock Purchase Agreement”), by and between MIRAGEN THERAPEUTICSCAPNIA, INC., a Delaware corporation (the “Company”) and ASPIRE CAPITAL FUND, LLC, an Illinois limited liability company (the “Buyer”), pursuant to which the Company may sell to the Buyer up to Twenty Ten Million Dollars ($20,000,00010,000,000) of the Company’s Common Stock, par value $0.01 0.001 (the “Common Stock”). Terms used herein and not otherwise defined shall have the meanings ascribed to them in the Common Stock Purchase Agreement. The undersigned, _________________ Xxxxxxx Xxxxxxx, Secretary of the Company, hereby certifies as follows in his capacity as such, hereby certifies as follows:

FORM OF SECRETARY’S CERTIFICATE. This Secretary’s Certificate (the “Certificate”) is being delivered pursuant to Section 7(k) of that certain Common Stock Purchase Agreement dated as of December __November 16, 2019 2017 (the “Common Stock Purchase Agreement”), by and between MIRAGEN THERAPEUTICS, IPASS INC., a Delaware corporation (the “Company”) and ASPIRE CAPITAL FUND, LLC, an Illinois limited liability company (the “Buyer”), pursuant to which the Company may sell to the Buyer up to Twenty Ten Million Dollars ($20,000,00010,000,000) of the Company’s Common Stock, par value $0.01 0.001 (the “Common Stock”). Terms used herein and not otherwise defined shall have the meanings ascribed to them in the Common Stock Purchase Agreement. The undersigned, _________________ Secretary of the Company, hereby certifies as follows in his capacity as such:

FORM OF SECRETARY’S CERTIFICATE. This Secretary’s Certificate (the “Certificate”) is being delivered pursuant to Section 7(k) of that certain Common Stock Purchase Agreement dated as of December __September 6, 2019 2017 (the “Common Stock Purchase Agreement”), by and between MIRAGEN THERAPEUTICS, INNOVATION PHARMACEUTICALS INC., a Delaware Nevada corporation (the “Company”) and ASPIRE CAPITAL FUND, LLC, an Illinois limited liability company (the “Buyer”), pursuant to which the Company may sell to the Buyer up to Twenty Thirty Million Dollars ($20,000,00030,000,000) of the Company’s Common Stock, par value $0.01 0.0001 (the “Common Stock”). Terms used herein and not otherwise defined shall have the meanings ascribed to them in the Common Stock Purchase Agreement. The undersigned, _________________ Secretary of the Company, hereby certifies as follows in his capacity as such:

FORM OF SECRETARY’S CERTIFICATE. This Secretary’s Certificate (the “Certificate”) is being delivered pursuant to Section 7(k) of that certain Common Stock Purchase Agreement dated as of December __October 24, 2019 (the “Common Stock Purchase Agreement”), by and between MIRAGEN THERAPEUTICSOCEAN POWER TECHNOLOGIES, INC., a Delaware corporation (the “Company”) and ASPIRE CAPITAL FUND, LLC, an Illinois limited liability company (the “Buyer”), pursuant to which the Company may sell to the Buyer up to Twenty Ten Million Dollars ($20,000,00010,000,000) of the Company’s Common Stock, par value $0.01 0.001 (the “Common Stock”). Terms used herein and not otherwise defined shall have the meanings ascribed to them in the Common Stock Purchase Agreement. The undersigned, _________________ , Secretary of the Company, hereby certifies as follows in his capacity as such:

FORM OF SECRETARY’S CERTIFICATE. This Secretary’s Certificate (the “Certificate”) is being delivered pursuant to Section 7(k) of that certain Common Stock Purchase Agreement dated as of December __15, 2019 2015 (the “Common Stock Purchase Agreement”), by and between MIRAGEN THERAPEUTICSHARVARD APPARATUS REGENERATIVE TECHNOLOGY, INC., a Delaware corporation (the “Company”) and ASPIRE CAPITAL FUND, LLC, an Illinois limited liability company (the “Buyer”), pursuant to which the Company may sell to the Buyer up to Twenty Fifteen Million Dollars ($20,000,00015,000,000) of the Company’s Common Stock, par value $0.01 (the “Common Stock”). Terms used herein and not otherwise defined shall have the meanings ascribed to them in the Common Stock Purchase Agreement. The undersigned, _________________ , Secretary of the Company, hereby certifies as follows in his capacity as such, hereby certifies as follows:

FORM OF SECRETARY’S CERTIFICATE. This Secretary’s Certificate (the “Certificate”) is being delivered pursuant to Section 7(k) of that certain Common Stock Purchase Agreement dated as of December August ____, 2019 2014 (the “Common Stock Purchase Agreement”), by and between MIRAGEN THERAPEUTICSLIQUIDMETAL TECHNOLOGIES, INC., a Delaware corporation (the “Company”) and ASPIRE CAPITAL FUND, LLC, an Illinois limited liability company (the “Buyer”), pursuant to which the Company may sell to the Buyer up to Twenty Thirty Million Dollars ($20,000,00030,000,000) of the Company’s Common Stock, par value $0.01 0.001 (the “Common Stock”). Terms used herein and not otherwise defined shall have the meanings ascribed to them in the Common Stock Purchase Agreement. The undersigned, _________________ , Secretary of the Company, hereby certifies as follows in his capacity as such, hereby certifies as follows:

FORM OF SECRETARY’S CERTIFICATE. This Secretary’s Certificate (the “Certificate”) is being delivered pursuant to Section 7(k) of that certain Common Stock Purchase Agreement dated as of December __October 21, 2019 (the “Common Stock Purchase Agreement”), by and between MIRAGEN THERAPEUTICS, ENTASIS THERAPEUTICS HOLDINGS INC., a Delaware corporation (the “Company”) and ASPIRE CAPITAL FUND, LLC, an Illinois limited liability company (the “Buyer”), pursuant to which the Company may sell to the Buyer up to Twenty Million Dollars ($20,000,000) of the Company’s Common Stock, par value $0.01 0.001 (the “Common Stock”). Terms used herein and not otherwise defined shall have the meanings ascribed to them in the Common Stock Purchase Agreement. The undersigned, _________________ Secretary of the Company, hereby certifies as follows in his his/her capacity as such:

FORM OF SECRETARY’S CERTIFICATE. This Secretary’s Certificate (the “Certificate”) is being delivered pursuant to Section 7(k) of that certain Common Stock Purchase Agreement dated as of December __July 31, 2019 2020 (the “Common Stock Purchase Agreement”), by and between MIRAGEN THERAPEUTICS, INNOVATION PHARMACEUTICALS INC., a Delaware Nevada corporation (the “Company”) and ASPIRE CAPITAL FUND, LLC, an Illinois limited liability company (the “Buyer”), pursuant to which the Company may sell to the Buyer up to Twenty Thirty Million Dollars ($20,000,00030,000,000) of the Company’s Common Stock, par value $0.01 0.0001 (the “Common Stock”). Terms Stock”).Terms used herein and not otherwise defined shall have the meanings ascribed to them in the Common Stock Purchase Agreement. The undersigned, _________________ Secretary of the Company, hereby certifies as follows in his capacity as such:

FORM OF SECRETARY’S CERTIFICATE. This Secretary’s Certificate (the this “Certificate”) is being delivered pursuant to Section 7(k) of that certain Common Stock Purchase Agreement dated as of December __November 4, 2019 2015 (the “Common Stock Purchase Agreement”), by and between MIRAGEN THERAPEUTICSCALADRIUS BIOSCIENCES, INC.Inc., a Delaware corporation (the “Company”) and ASPIRE CAPITAL FUND, LLC, an Illinois limited liability company (the “Buyer”), pursuant to which the Company may sell to the Buyer up to Twenty Thirty Million Dollars ($20,000,00030,000,000) of the Company’s Common Stock, par value $0.01 0.001 (the “Common Stock”). Terms used herein and not otherwise defined shall have the meanings ascribed to them in the Common Stock Purchase Agreement. The undersigned, _________________ Xxxx Xxxxxxxx, Secretary of the Company, hereby certifies as follows in his capacity as suchfollows:

FORM OF SECRETARY’S CERTIFICATE. This Secretary’s Certificate (the “Certificate”) is being delivered pursuant to Section 7(k) of that certain Common Stock Purchase Agreement dated as of December __July 5, 2019 2016 (the “Common Stock Purchase Agreement”), by and between MIRAGEN THERAPEUTICSAPRICUS BIOSCIENCES, INC., a Delaware Nevada corporation (the “Company”) and ASPIRE CAPITAL FUND, LLC, an Illinois limited liability company (the “Buyer”), pursuant to which the Company may sell to the Buyer up to Twenty Seven Million Dollars ($20,000,0007,000,000) of the Company’s Common Stock, par value $0.01 0.001 (the “Common Stock”). Terms used herein and not otherwise defined shall have the meanings ascribed to them in the Common Stock Purchase Agreement. The undersigned, _________________ , Secretary of the Company, hereby certifies as follows in his capacity as such:

FORM OF SECRETARY’S CERTIFICATE. This Secretary’s Certificate (the “Certificate”) is being delivered pursuant to Section 7(k) of that certain Common Stock Purchase Agreement dated as of December __March , 2019 2014 (the “Common Stock Purchase Agreement”), by and between MIRAGEN THERAPEUTICSNANOSPHERE, INC., a Delaware corporation (the “Company”) and ASPIRE CAPITAL FUND, LLC, an Illinois limited liability company (the “Buyer”), pursuant to which the Company may sell to the Buyer up to Twenty Thirty Million Dollars ($20,000,00030,000,000) of the Company’s Common Stock, par value $0.01 (the “Common Stock”). Terms used herein and not otherwise defined shall have the meanings ascribed to them in the Common Stock Purchase Agreement. The undersigned, _________________ Secretary of the Company, hereby certifies as follows in his capacity as such:

FORM OF SECRETARY’S CERTIFICATE. This Secretary’s Certificate (the “Certificate”) is being delivered pursuant to Section 7(k) of that certain Common Stock Purchase Agreement dated as of December __March 31, 2019 2014 (the “Common Stock Purchase Agreement”), by and between MIRAGEN THERAPEUTICSMOBIQUITY TECHNOLOGIES, INC., a Delaware New York corporation (the “Company”) and ASPIRE CAPITAL FUND, LLC, an Illinois limited liability company (the “Buyer”), pursuant to which the Company may sell to the Buyer up to Twenty Fifteen Million Dollars ($20,000,00015,000,000) of the Company’s Common Stock, par value $0.01 0.0001 (the “Common Stock”). Terms used herein and not otherwise defined shall have the meanings ascribed to them in the Common Stock Purchase Agreement. The undersigned, _________________ , Secretary of the Company, hereby certifies as follows in his capacity as such, hereby certifies as follows:

FORM OF SECRETARY’S CERTIFICATE. This Secretary’s Certificate (the “Certificate”) is being delivered pursuant to Section 7(k) of that certain Common Stock Purchase Agreement dated as of December __October 28, 2019 (the “Common Stock Purchase Agreement”), by and between MIRAGEN THERAPEUTICS, INC.CELSION CORPORATION, a Delaware corporation (the “Company”) and ASPIRE CAPITAL FUND, LLC, an Illinois limited liability company (the “Buyer”), pursuant to which the Company may sell to the Buyer up to Twenty Ten Million Dollars ($20,000,00010,000,000) of the Company’s Common Stock, par value $0.01 (the “Common Stock”). Terms used herein and not otherwise defined shall have the meanings ascribed to them in the Common Stock Purchase Agreement. The undersigned, _________________ Jxxxxxx X. Xxxxxx, in his capacity as Secretary of the Company, and not individually, hereby certifies as follows in his capacity as such:

FORM OF SECRETARY’S CERTIFICATE. This Secretary’s Certificate (the “Certificate”) is being delivered pursuant to Section 7(k) of that certain Common Stock Purchase Agreement dated as of December __September 25, 2019 2017 (the “Common Stock Purchase Agreement”), by and between MIRAGEN THERAPEUTICSWESTWATER RESOURCES, INC., a Delaware corporation (the “Company”) and ASPIRE CAPITAL FUND, LLC, an Illinois limited liability company (the “Buyer”), pursuant to which the Company may sell to the Buyer up to Twenty Twenty-two Million Dollars ($20,000,00022,000,000) of the Company’s Common Stock, par value $0.01 0.001 (the “Common Stock”). Terms used herein and not otherwise defined shall have the meanings ascribed to them in the Common Stock Purchase Agreement. The undersigned, _________________ Secretary of the Company, hereby certifies as follows in his capacity as such:

FORM OF SECRETARY’S CERTIFICATE. This Secretary’s Certificate (the “Certificate”) is being delivered pursuant to Section 7(k) of that certain Common Stock Purchase Agreement dated as of December __June , 2019 2016 (the “Common Stock Purchase Agreement”), by and between MIRAGEN THERAPEUTICSJAGUAR ANIMAL HEALTH, INC., a Delaware corporation (the “Company”) and ASPIRE CAPITAL FUND, LLC, an Illinois limited liability company (the “Buyer”), pursuant to which the Company may sell to the Buyer up to Twenty Fifteen Million Dollars ($20,000,00015,000,000) of the Company’s Common Stock, par value $0.01 0.0001 (the “Common Stock”). Terms used herein and not otherwise defined shall have the meanings ascribed to them in the Common Stock Purchase Agreement. The undersigned, _________________ , Secretary of the Company, hereby certifies as follows in his capacity as such, hereby certifies as follows:

FORM OF SECRETARY’S CERTIFICATE. This Secretary’s Certificate (the “Certificate”) is being delivered pursuant to Section 7(k) of that certain Common Stock Purchase Agreement dated as of December __April 23, 2019 2013 (the “Common Stock Purchase Agreement”), by and between MIRAGEN THERAPEUTICSCOPYTELE, INC., a Delaware corporation (the “Company”) and ASPIRE CAPITAL FUND, LLC, an Illinois limited liability company (the “Buyer”), pursuant to which the Company may sell to the Buyer up to Twenty Ten Million Dollars ($20,000,00010,000,000) of the Company’s Common Stock, par value $0.01 (the “Common Stock”). Terms used herein and not otherwise defined shall have the meanings ascribed to them in the Common Stock Purchase Agreement. The undersigned, _________________ Secretary of the Company, hereby certifies as follows in his capacity as such: