Common use of Date of Amendment Clause in Contracts

Date of Amendment. This amendment is dated as of the date this amendment is signed by the second of the two parties to sign this amendment (as indicated by the dates written under each party’s signature to this amendment). This amendment will be void unless Advanced BioHealing returns this amendment bearing its signature to Ethicon by July 31, 2009. ETHICON, INC. ADVANCED BIOHEALING, INC. By: /s/ Xxxxxxx Xxxxx By: /s/ Xxxxx XxXxx Name: Xxxxxxx Xxxxx Name: Xxxxx XxXxx Title: Director, Nat’l Accounts Distribution Title: VP, General Manager

Date of Amendment. This amendment is dated as of the date this amendment is signed by the second of the two parties to sign this amendment (as indicated by the dates written under each party’s signature to this amendment). This amendment will be void unless Advanced BioHealing returns this amendment bearing its signature to Ethicon by July 31February 28, 20092011. ETHICON, INC. ADVANCED BIOHEALING, INC. By: /s/ Xxxxxxx Xxxxx By: /s/ Xxxxx XxXxx Name: Xxxxxxx Xxxxx Name: Xxxxx XxXxx Title: Director, Nat’l Accounts Distribution Title: VPSenior Vice President, General ManagerOperations

Date of Amendment. This amendment is dated as of the date this amendment is signed by the second of the two parties to sign this amendment (as indicated by the dates written under each party’s signature to this amendment). This amendment will be void unless Advanced BioHealing returns this amendment bearing its signature to Ethicon by July 31February 28, 20092011. ETHICON, INC. ADVANCED BIOHEALING, INC. By: /s/ Xxxxxxx Xxxxx By: /s/ Xxxxx XxXxx Name: Xxxxxxx Xxxxx Name: Xxxxx XxXxx Title: Director, Nat’l Accounts Distribution Title: VPSenior Vice President, General ManagerOperations Date: 03/01/2011 Date: 02/24/2011 *** Certain information on this page has been omitted and filed separately with the Securities and Exchange Commission.