Exhibit 1.1 4,000,000 SHARES THE MEDICINES COMPANY COMMON STOCK, $.001 PAR VALUE PER SHARE UNDERWRITING AGREEMENTMedicines Co /De • March 13th, 2003 • Pharmaceutical preparations • New York
1 EXHIBIT 10.19 THIS WARRANT AND THE SHARES OF COMMON STOCK ISSUED UPON ITS EXERCISE ARE SUBJECT TO THE RESTRICTIONS ON TRANSFER SET FORTH IN SECTION 4 OF THIS WARRANTMedicines Co/ Ma • May 19th, 2000 • Massachusetts
R E C I T A L SStockholders' Agreement • May 19th, 2000 • Medicines Co/ Ma • Delaware
LEASE FROM:Lease • March 5th, 2003 • Medicines Co /De • Pharmaceutical preparations
LEASE FROM:Agreement • March 5th, 2004 • Medicines Co /De • Pharmaceutical preparations
EXHIBIT 10.2 TERMINATION AGREEMENT This Agreement (the "Termination Agreement") made this 1st day of November 2001, is entered into by and between The Medicines Company, a Delaware corporation with its principal place of business at One Cambridge...Termination Agreement • November 14th, 2001 • Medicines Co/ Ma • Pharmaceutical preparations • New Jersey
EXHIBIT 10.4 AMENDED AND RESTATED EMPLOYMENT AGREEMENT THIS EMPLOYMENT AGREEMENT (the "Agreement"), made this 1st day of November, 2001, is entered into by The Medicines Company, a Delaware corporation with its principal place of business at One...Employment Agreement • November 14th, 2001 • Medicines Co/ Ma • Pharmaceutical preparations • New Jersey
EXHIBIT 10.3 AMENDMENT TO EMPLOYMENT AGREEMENT This Amendment to Employment Agreement (this "Amendment"), made as of the 10th day of July, 2001, is entered into by The Medicines Company, a Delaware corporation with its principal place of business at...Employment Agreement • November 14th, 2001 • Medicines Co/ Ma • Pharmaceutical preparations • Massachusetts
RECITALSLoan and Security Agreement • May 15th, 2002 • Medicines Co/ Ma • Pharmaceutical preparations • California
EXHIBIT 10.14 EMPLOYMENT AGREEMENT THIS EMPLOYMENT AGREEMENT (the "Agreement"), made this 29th day of September, 1998 is entered into by The Medicines Company, a Delaware corporation with its principal place of business at One Cambridge Center,...Employment Agreement • May 19th, 2000 • Medicines Co/ Ma • Massachusetts
FROMMedicines Co/ Ma • May 19th, 2000 • Massachusetts
ContractMedicines Co /De • June 28th, 2019 • Pharmaceutical preparations • New York
EXHIBIT 10.18 Confidential Materials omitted and filed separately with the Securities and Exchange Commission. Asterisks denote omissions. LICENSE AGREEMENT Entered into by and between AstraZeneca AB and The Medicines Company as of the 18th day of...License Agreement • March 5th, 2004 • Medicines Co /De • Pharmaceutical preparations • England
THE MEDICINES COMPANY AND WELLS FARGO BANK, NATIONAL ASSOCIATION, as Trustee INDENTURE Dated as of December 18, 2018 3.50% Convertible Senior Notes due 2024Indenture • December 18th, 2018 • Medicines Co /De • Pharmaceutical preparations • New York
INDENTURE dated as of December 18, 2018 between THE MEDICINES COMPANY, a Delaware corporation, as issuer (the “Company”, as more fully set forth in Section 1.01) and WELLS FARGO BANK, NATIONAL ASSOCIATION, a national banking association, as trustee (the “Trustee”, as more fully set forth in Section 1.01).
1 EXHIBIT 10.20 THIS WARRANT AND THE SHARES OF COMMON STOCK ISSUED UPON ITS EXERCISE ARE SUBJECT TO THE RESTRICTIONS ON TRANSFER SET FORTH IN SECTION 4 OF THIS WARRANTMedicines Co/ Ma • May 19th, 2000 • Massachusetts
EXHIBIT 10.6 LICENSE AGREEMENT ----------------- This Agreement, made and entered into this 6th day of June 1990, by and between Biogen, Inc. a Massachusetts corporation, of 14 Cambridge Center, Cambridge, MA 02142 ("BIOGEN") and Health Research,...License Agreement • August 4th, 2000 • Medicines Co/ Ma • Pharmaceutical preparations • Massachusetts
Exhibit 10.1 AMENDED AND RESTATED REGISTRATION RIGHTS AGREEMENT This Agreement is made and entered into as of this 12th day of August, 1998, by and among The Medicines Company, a Delaware corporation (the "Company"), the individuals and entities...Registration Rights Agreement • August 14th, 2002 • Medicines Co/ Ma • Pharmaceutical preparations • Delaware
EXHIBIT 10.1 AMENDED AND RESTATED EMPLOYMENT AGREEMENT THIS EMPLOYMENT AGREEMENT (the "Agreement"), made this 27th day of February, 2002, is entered into by The Medicines Company, a Delaware corporation with its principal place of business at Five...Employment Agreement • May 15th, 2002 • Medicines Co/ Ma • Pharmaceutical preparations • Massachusetts
1 Exhibit 10.17 EMPLOYMENT AGREEMENT -------------------- THIS EMPLOYMENT AGREEMENT (the "Agreement"), made this 30th day of March, is entered into by The Medicines Company, a Delaware corporation with its principal place of business at One Cambridge...Employment Agreement • May 19th, 2000 • Medicines Co/ Ma • Massachusetts
1 EXHIBIT 10.26 EMPLOYMENT AGREEMENT -------------------- THIS EMPLOYMENT AGREEMENT (the "Agreement"), made this 1st day of April, is entered into by The Medicines Company, a Delaware corporation with its principal place of business at One Cambridge...Employment Agreement • January 5th, 2001 • Medicines Co/ Ma • Pharmaceutical preparations • Massachusetts
CHEMILOG DEVELOPMENT AND SUPPLY AGREEMENT BETWEEN UCB-BIOPRODUCTS S.A., with registered office at Allee de la Recherche 60, B-1070 Brussels, Belgium ("UCB")Medicines Co/ Ma • August 4th, 2000 • Pharmaceutical preparations
Exhibit 10.17 Confidential Materials omitted and filed separately with the Securities and Exchange Commission. Asterisks denote omissions. 10 April, 2003 The Medicines Company 8 Campus Drive Parsippany New Jersey 07054 United States Att: Clive...Option Agreement • March 5th, 2004 • Medicines Co /De • Pharmaceutical preparations • England
BACKGROUND:Master Services Agreement • February 23rd, 2001 • Medicines Co/ Ma • Pharmaceutical preparations • New Jersey
1 THE MEDICINES COMPANY 5,000,000 Shares of Common Stock Underwriting AgreementMedicines Co/ Ma • July 21st, 2000 • Pharmaceutical preparations • New York
1 EXHIBIT 10.16 EMPLOYMENT AGREEMENT THIS EMPLOYMENT AGREEMENT (the "Agreement"), made this 20th day of October, 1997, is entered into by The Medicines Company, a Delaware corporation with its principal place of business at One Cambridge Center,...Employment Agreement • May 19th, 2000 • Medicines Co/ Ma • Massachusetts
ANDMedicines Co /De • August 5th, 2003 • Pharmaceutical preparations
INDEMNITY AGREEMENTIndemnity Agreement • December 23rd, 2015 • Medicines Co /De • Pharmaceutical preparations • Delaware
THIS INDEMNITY AGREEMENT (this “Agreement”) is made as of , 2015, by and between The Medicines Company, a Delaware corporation (the “Company”), and (“Indemnitee”).
Exhibit 1.1 4,000,000 Shares of Common Stock THE MEDICINES COMPANY UNDERWRITING AGREEMENT June 20, 2002 BEAR, STEARNS & CO. INC. 383 Madison Avenue New York, New York 10179 Ladies and Gentlemen: The Medicines Company, a corporation organized and...Underwriting Agreement • June 25th, 2002 • Medicines Co/ Ma • Pharmaceutical preparations • New York
EXHIBIT 10.1 ASSIGNMENT AND ASSUMPTION OF LEASE THIS ASSIGNMENT AND ASSUMPTION OF LEASE (this "Assignment") is made this 18th day of October, 2001 from STACK PHARMACEUTICALS, INC., having an office at 5 Sylvan Way, Parsippany, New Jersey 07054...Assignment and Assumption of Lease • November 14th, 2001 • Medicines Co/ Ma • Pharmaceutical preparations
EXHIBIT 10.10 ALLIANCE AGREEMENT This Alliance Agreement (this "Agreement") is made and entered into as of the ____ day of August 1996, by and between Medicines Development Company, a Delaware corporation (the "Company"), and PharmaBio Development...Alliance Agreement • August 4th, 2000 • Medicines Co/ Ma • Pharmaceutical preparations • North Carolina
CHEMILOG DEVELOPMENT AND SUPPLY AGREEMENT BETWEEN UCB-BIOPRODUCTS S.A., with registered office at Allee de la Recherche 60, B-1070 Brussels, Belgium ("UCB")Medicines Co/ Ma • May 19th, 2000
EXHIBIT 10.3 CONFIDENTIAL MATERIALS OMITTED AND FILED SEPARATELY WITH THE SECURITIES AND EXCHANGE COMMISSION. ASTERISKS DENOTE OMISSIONS. SALES, MARKETING AND DISTRIBUTION AGREEMENT This Agreement is made 25th March 2002 (the "Effective Date") by and...Marketing and Distribution Agreement • May 15th, 2002 • Medicines Co/ Ma • Pharmaceutical preparations • Massachusetts
1 EXHIBIT 10.29 AMENDMENT NO. 2 TO THE SERVICES AGREEMENT This Amendment No. 2 (the "Amendment") to the Services Agreement dated April 1, 2000, as amended August 8, 2000 (the "Agreement"), among The Medicines Company, a Delaware corporation (the...The Services Agreement • June 19th, 2001 • Medicines Co/ Ma • Pharmaceutical preparations
August 17, 2006 [Name] [Title] The Medicines Company 8 Campus Drive Parsippany, NJ 07054 Dear [Name]:Medicines Co /De • March 1st, 2007 • Pharmaceutical preparations
This letter agreement amends and restates in its entirety the letter agreement between you and The Medicines Company (the “Company”) dated December 21, 2005 regarding the subject matter hereof.
Confidential Materials omitted and filed separately with the Securities and Exchange Commission. Double asterisks denote omissions. AGREEMENT AND PLAN OF MERGER by and among THE MEDICINES COMPANY, SILVER SURFER ACQUISITION CORP., FORTIS ADVISORS LLC...Agreement and Plan of Merger • January 10th, 2013 • Medicines Co /De • Pharmaceutical preparations • Delaware
THIS AGREEMENT AND PLAN OF MERGER (this “Agreement”) is entered into as of December 11, 2012, by and among The Medicines Company, a Delaware corporation (the “Buyer”), Silver Surfer Acquisition Corp., a Delaware corporation and a wholly owned subsidiary of the Buyer (the “Transitory Subsidiary”), Fortis Advisors LLC, a Delaware limited liability company, solely in its capacity as the Representative (the “Representative”), and Incline Therapeutics, Inc., a Delaware corporation (the “Company”). The Buyer, the Transitory Subsidiary, the Company and the Representative are sometimes referred to herein individually as a “Party” and collectively as the “Parties”. All capitalized terms used in this Agreement shall have the meanings given to them in Section 9.1.
