Validated Target definition

Validated Target means a Target that has been validated in vitro ---------------- or in vivo as part of a TVD program by ATUGEN or its Collaborator.
Validated Target means a biological drug target against which any drug has received Marketing Authorization Approval.
Validated Target means a Target which has been shown to meet all of the following criteria approved by the PC: (a) the Target is well characterized (i.e., its biochemical and physiological actions are reasonably well understood); (b) agents, ligands, or intracellular molecules that interact with the Target demonstrate a desired effect on a biological process in relationship to a disease state or disorder; and (c) the Target is shown to be present in human tissue with the disease state or condition.

Examples of Validated Target in a sentence

  • At any time during the Exclusivity Term with respect to a Novel Validated Target, Novartis shall on a not less than quarterly basis provide documentation to the reasonable satisfaction of Rigel that Novartis is maintaining a diligent, continuous program with respect to the Novel Validated Target.

  • Rigel shall notify the CMC in writing of each Novel Validated Target identified by Rigel during the Research Period of each Joint Project promptly after its identification.

  • Novartis shall have the right to initiate Compound Screening with each Novel Validated Target upon notice to Rigel any time during the Exclusivity Term with respect to such Novel Validated Target.

  • At any time during the Exclusivity Term with respect to a Novel Validated Target, Novartis, at its sole discretion, may request in writing that Rigel conduct Compound Screening of Rigel's small-molecule compound library against such Novel Validated Target.

  • We also notice that when M equals 3, the performance decreases and the running speed slows down by large margin.


More Definitions of Validated Target

Validated Target means the *** .
Validated Target means any one or more of the following: (i) NMDA channels, (ii) sodium channels, and/or (iii) both NMDA and sodium channels, if so designated by the Research Management Committee pursuant to Section 4.1, or other glutamate-activated channels that the Research Management Committee determines from time to time.
Validated Target. Validated Target shall mean a Target having one or both of the following features: (1) [*]; and/or (2) [*]. The Party submitting a Validated Target having either feature will have made reasonable efforts to [*].
Validated Target means a Target which has been shown to meet all of the following criteria approved by the PC:
Validated Target has the meaning forth in Section 2.1.3.
Validated Target means a biological molecule that (a) is a [**], a Protein [**] by a [**] or another qualifying biological molecule in a relevant [**] of which or the [**] is based upon the identification of a [**], and (b) that (i) has been configured into a research assay that is suitable for the [**] and which research assay is (1) a biochemical assay (including without limitation, a competitive binding assay for a receptor or an enzyme substrate conversion assay), or (2) a reporter based assay, in either case having a robust assay readout (such as fluorescence, chemiluminescence, and/or radioactivity) that has the potential to be configured into a high throughput screen and is therefore suitable for undertaking research activities to develop a high throughput screen, or (ii) is suitable for use in [**] or (iii) is suitable for use in [**] development efforts, all as determined in good faith by the Joint Management Team. Unless stated otherwise, a Validated Target shall include a Genetics Validated Target.
Validated Target means either an In Vitro Validated Target and/or an In Vivo Validated Target.