Prodrug definition

Prodrug means a chemical precursor of PRODUCT which is to be cleaved in a human being directly into PRODUCT and/or a metabolic intermediate thereof, but excluding for greater certainty, antigen processing;

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Prodrug means any compounds which, following administration, are actively converted in the body to Compound A or Compound B.

Prodrug means different pharmaceutical compounds which, following administration, are converted into structurally similar active metabolites.

Examples of Prodrug in a sentence

The royalty shall be [...***...] percent ([...***...]%) of the Net Sales for those Products containing a Compound, and shall be [...***...] percent ([...***...]%) of the Net Sales for those Products containing a Prodrug or Metabolite.
If this Agreement is terminated by Anadys under this Section 6.3 for the willful breach by Licensors of Section 4.1, 4.2, 4.3 or 4.4, then the financial obligations of Anadys and its sublicensees under this Agreement with respect to the Compound, Metabolite, Prodrug affected by such breach shall be extinguished and Anadys shall have a fully paid-up, worldwide, irrevocable, exclusive license to (a) such Compound, Prodrug, and/or Metabolite, and (b) to the Intellectual Property Rights associated therewith.
In February 1999, the Company entered into an exclusive license agreement with SmithKline ▇▇▇▇▇▇▇ plc, London and SmithKline ▇▇▇▇▇▇▇, Philadelphia, wholly-owned subsidiaries of GlaxoSmithKline (collectively, SB) to develop and commercialize ImmunoGen's lead Tumor Activated Prodrug (or TAP), huC242-DM1 (the SB Agreement) for the treatment of colorectal, pancreatic and certain non-small lung cancers.
SGI shall own all right, title and interest in all SGI Technology (including without limitation all SGI Prodrug Inventions and SGI Prodrug Patents).
Omthera desires to license from Licensor and Licensor wishes to license to Omthera, on an exclusive basis, the right to develop and commercialize Licensor Liver Targeting Prodrug Technology prodrugs comprising the Compounds.

More Definitions of Prodrug

Prodrug means a compound that may or may not be pharmacologically active that undergoes an in vivo metabolism producing a second compound exhibiting a pharmacological effect. By way of example only, arbaclofen placarbil is a Prodrug of R-baclofen, i.e., arbaclofen placarbil is metabolized in vivo to form R-baclofen.

Prodrug means a compound which is designed to be converted, subsequent to administration to a patient, by metabolic processes to a different compound having anti-infective pharmacological activity.

Prodrug means, with respect to a compound, a composition of matter that is designed to have such compound as its only primary Major Metabolite.

Prodrug means a compound that is initially administered to the body in an inactive (or less than fully active) form, and then becomes converted to its active form through the normal metabolic processes of the body and non-metabolic processes such as pH or hydrolysis driven cleavage processes and intrinsic cleavage based on an internal cyclization-cleavage mechanism.

Prodrug means different pharmaceutical compounds which, following administration, are converted into structurally similar active metabolites that are similar to or act in a similar manner as the Compound.

Prodrug. The term “

Prodrug means any chemical entity that upon or after administration to a human is transformed into a Compound, wherein said Compound and/or its metabolites are substantially the only pharmaceutically active metabolic products.