Pharmacogenomics definition

Pharmacogenomics. ’ means the study of indi-

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Pharmacogenomics shall have the same meaning set forth in the Technology Transfer and License Agreement executed by and between Axys Pharmaceuticals, Inc. and the Corporation effective as of February 1, 1999.

Pharmacogenomics means the study of the pharmacological correlation between drug response and variations in genetic elements has become of increasing importance for drug development. Such variations can have effects on the risk of developing adverse drug reactions as well as on the response to treatment. Variations in drug pharmacokinetics and metabolic pathways can cause higher drug concentrations in some patients, resulting in increased drug toxicity, and/or lower drug concentrations in some patients, resulting in decreased drug effects.

Examples of Pharmacogenomics in a sentence

Designated Products" are all existing and future Pharmacogenomics software programs, documentation, information and information systems, sequences, sample collections, technology and methods, including Enhancements, developed or licensed by the Corporation and which the Corporation makes available for sale or licensing, as the case may be, from time to time.
In 2011, the Clinical Pharmacogenomics Implementation Consortium (CPIC) was founded [3].
Designated Services" are all existing and future Pharmacogenomics contract, consulting, research and development, laboratory, and technical and maintenance support services, including Enhancements (as hereinafter defined), offered by or available to the Corporation from time to time.
The latter contain nearly all variants from the DMET and Illumina ADME core panel, in addition to all genes and variants with clinical annotations in CPIC and PharmGKB (Pharmacogenomics knowledge base), HLA genes and sample ID and tracking markers.
Each Party will attempt to accommodate any reasonable request of the other Party to send or receive personnel for purposes of collaborating or exchanging information under the Pharmacogenomics Program.

More Definitions of Pharmacogenomics

Pharmacogenomics means the correlation, based on analysis of animal and/or human tissue (including, without limitation, cell lines), of a biological marker (e.g., DNA, RNA or protein) with measurements of the safety and/or efficacy of a preventative and/or therapeutic substance or candidate.

Pharmacogenomics means the science related to the identification and elucidation of genetic variations that correlate with an the individual's response and reaction to specific drugs and using specific nucleotide sequences to alter expression of selected genes to achieve a therapeutic result.

Pharmacogenomics or "PGX" means the gathering and use of genetic and other related information, whether from a population, an individual or animals, to (i) predict the safety, toxicity and/or efficacy of drugs for humans as part of a drug discovery and development program or as part of an individual's diagnosis and treatment regimen; or (ii) to determine or predict the susceptibility or disposition of an individual to disease, disease complications, and disease course. By way of illustration and not limitation, "Pharmacogenomics" includes identification of candidate genes and polymorphisms, correlation of polymorphisms to clinical outcomes and drug effects, development of novel algorithms and informatics tools in connection with such identification and correlation, and clinical diagnostics, such as prediction of drug response or selection and dosing of drugs based on genotype and/or expression, i.e., phenotype, as well as the development of genetic tests or screens for use in predicting susceptibility to disease, disease complications and disease course.

Pharmacogenomics means the study of the relationship between a specific person's

Pharmacogenomics shall have the meaning set forth in the Technology Transfer and License Agreement executed by and between Axys Pharmaceuticals, Inc. and PPGx, Inc. on February 1, 1999.

Pharmacogenomics means the evaluation of how a person’s genes affect how the person responds to medications. Pharmacogenomics enables the selection of drugs and doses best suited to reduce toxicity and adverse drug events, including treatment failures, severe harm, or even death;

Pharmacogenomics means compositions, assays and methods useful for predicting the safety, toxicity and/or efficacy of drugs for humans as part of a drug discovery and development program or as part of an individual's diagnosis and treatment regimen but excluding predicting modes of function of a therapeutic.