EXHIBIT 10.4 GENZYME TRANSGENICS CORPORATION CONSULTING AGREEMENT This Consulting Agreement dated as of July 1, 1998 is between James A. Geraghty (the "Consultant") and Genzyme Transgenics Corporation (the "Company"), a Delaware corporation. In...Consulting Agreement • November 12th, 1998 • Genzyme Transgenics Corp • Biological products, (no disgnostic substances) • Massachusetts
Contract Type FiledNovember 12th, 1998 Company Industry Jurisdiction
W I T N E S S E T H:Loan Agreement • August 13th, 1997 • Genzyme Transgenics Corp • Biological products, (no disgnostic substances) • Arkansas
Contract Type FiledAugust 13th, 1997 Company Industry Jurisdiction
EIGHTH AMENDMENT TO REVOLVING CREDIT AGREEMENT THIS EIGHTH AMENDMENT TO REVOLVING CREDIT AGREEMENT (this "Eighth Amendment") is made and entered into as of March 20, 1998, by and among GENZYME TRANSGENICS CORPORATION, a Massachusetts corporation...Revolving Credit Agreement • March 27th, 1998 • Genzyme Transgenics Corp • Biological products, (no disgnostic substances) • Massachusetts
Contract Type FiledMarch 27th, 1998 Company Industry Jurisdiction
REGISTRATION RIGHTS AGREEMENTRegistration Rights Agreement • August 8th, 2005 • GTC Biotherapeutics Inc • Biological products, (no disgnostic substances)
Contract Type FiledAugust 8th, 2005 Company IndustryThis Agreement is made pursuant to the Securities Purchase Agreement, dated as of the date hereof among the Company and the Purchasers (the “Purchase Agreement”).
Exhibit 10.28.4 AMENDED AND RESTATED SECURITY AGREEMENT THIS AMENDED AND RESTATED SECURITY AGREEMENT dated as of December 28, 1998 (this "Agreement") among GENZYME CORPORATION, a Massachusetts corporation having its principal offices at One Kendall...Security Agreement • April 4th, 2000 • Genzyme Transgenics Corp • Biological products, (no disgnostic substances) • Massachusetts
Contract Type FiledApril 4th, 2000 Company Industry Jurisdiction
ARTICLE 1 EMPLOYMENT OF EXECUTIVEExecutive Employment Agreement • March 28th, 2003 • GTC Biotherapeutics Inc • Biological products, (no disgnostic substances) • Massachusetts
Contract Type FiledMarch 28th, 2003 Company Industry Jurisdiction
EXHIBIT 10.52.1 AMENDED AND RESTATED OPERATING AGREEMENTOperating Agreement • March 27th, 1998 • Genzyme Transgenics Corp • Biological products, (no disgnostic substances) • Delaware
Contract Type FiledMarch 27th, 1998 Company Industry Jurisdiction
Exhibit 10.26.3 Second Amendment to Lease Agreement This second amendment to Lease Agreement ("AGREEMENT") made and entered into this 7th day of July, 1997 by and between W. M. Rickman Construction Company ("LANDLORD") and Genzyme Transgenics...Lease Agreement • March 27th, 1998 • Genzyme Transgenics Corp • Biological products, (no disgnostic substances)
Contract Type FiledMarch 27th, 1998 Company Industry
Exhibit 10.51.4 FIRST AMENDMENT TO CREDIT AGREEMENT Reference is hereby made to that certain Credit Agreement dated as of December 28, 1998, by and between Genzyme Transgenics Corporation (the "Borrower"), and Fleet National Bank ("Lender") (as...Credit Agreement • April 4th, 2000 • Genzyme Transgenics Corp • Biological products, (no disgnostic substances) • Massachusetts
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GENZYME TRANSGENICS CORPORATION FEBRUARY 6, 2001 STOCK PURCHASE AGREEMENTStock Purchase Agreement • March 13th, 2001 • Genzyme Transgenics Corp • Biological products, (no disgnostic substances) • Delaware
Contract Type FiledMarch 13th, 2001 Company Industry Jurisdiction
Exhibit 10.54 SECURITIES PURCHASE AGREEMENT This SECURITIES PURCHASE AGREEMENT (this "Agreement"), dated as of March 20, 1998, by and between GENZYME TRANSGENICS CORPORATION, a Massachusetts corporation, with headquarters located at Five Mountain...Securities Purchase Agreement • March 27th, 1998 • Genzyme Transgenics Corp • Biological products, (no disgnostic substances) • New York
Contract Type FiledMarch 27th, 1998 Company Industry Jurisdiction
EXHIBIT 10.28.2 FIRST AMENDMENT TO SECURITY AGREEMENT This FIRST AMENDMENT TO SECURITY AGREEMENT is dated as of December 15, 1997 (this "First Amendment"), by GENZYME TRANSGENICS CORPORATION, a Massachusetts corporation with its principal place of...Security Agreement • March 27th, 1998 • Genzyme Transgenics Corp • Biological products, (no disgnostic substances) • Massachusetts
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MODIFICATION OF RESERVE PLEDGE AND SECURITY AGREEMENTPledge and Security Agreement • March 27th, 1998 • Genzyme Transgenics Corp • Biological products, (no disgnostic substances)
Contract Type FiledMarch 27th, 1998 Company Industry
EXHIBIT 10.2 CONFIDENTIAL MATERIALS OMITTED AND FILED SEPARATELY WITH THE SECURITIES AND EXCHANGE COMMISSION. ASTERISKS DENOTE SUCH OMISSIONS. PURCHASE AGREEMENTPurchase Agreement • November 13th, 2001 • Genzyme Transgenics Corp • Biological products, (no disgnostic substances) • Massachusetts
Contract Type FiledNovember 13th, 2001 Company Industry Jurisdiction
RECITALSSublease Agreement • August 2nd, 2002 • GTC Biotherapeutics Inc • Biological products, (no disgnostic substances) • Massachusetts
Contract Type FiledAugust 2nd, 2002 Company Industry Jurisdiction
COMMON STOCK PURCHASE WARRANT To Purchase Shares of Common Stock of GTC BIOTHERAPEUTICS, INC.GTC Biotherapeutics Inc • August 8th, 2005 • Biological products, (no disgnostic substances)
Company FiledAugust 8th, 2005 IndustryTHIS COMMON STOCK PURCHASE WARRANT (the “Warrant”) certifies that, for value received, (the “Holder”), is entitled, upon the terms and subject to the limitations on exercise and the conditions hereinafter set forth, at any time on or after February 9, 2006 (the “Initial Exercise Date”) and on or prior to the close of business on the fifth anniversary of the Initial Exercise Date (the “Termination Date”) but not thereafter, to subscribe for and purchase from GTC Biotherapeutics, Inc., a Massachusetts corporation (the “Company”), up to shares (the “Warrant Shares”) of Common Stock, par value $0.01 per share, of the Company (the “Common Stock”). The purchase price of one share of Common Stock under this Warrant shall be equal to the Exercise Price, as defined in Section 2(b).
AMENDMENT AGREEMENTAmendment Agreement • May 14th, 1997 • Genzyme Transgenics Corp • Biological products, (no disgnostic substances)
Contract Type FiledMay 14th, 1997 Company Industry
EXHIBIT 10.57.1 CREDIT AGREEMENTCredit Agreement • April 5th, 1999 • Genzyme Transgenics Corp • Biological products, (no disgnostic substances) • Massachusetts
Contract Type FiledApril 5th, 1999 Company Industry Jurisdiction
EXHIBIT 10.1 EMPLOYMENT AGREEMENT (Sandra Nusinoff Lehrman, M.D.) This Employment Agreement ("Agreement"), effective as of July 1, 1998, by and between Genzyme Transgenics Corporation (together with its affiliates and subsidiaries, "GTC"), a...Employment Agreement • August 11th, 1998 • Genzyme Transgenics Corp • Biological products, (no disgnostic substances) • Massachusetts
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Exhibit 10.3.2 CONFIDENTIAL MATERIALS OMITTED AND FILED SEPARATELY WITH THE SECURITIES AND EXCHANGE COMMISSION. ASTERISKS DENOTE SUCH OMISSIONS. CONFIDENTIAL DOCUMENT AMENDED AND RESTATED LICENSE AGREEMENT THIS AMENDED AND RESTATED LICENSE AGREEMENT...License Agreement • August 2nd, 2002 • GTC Biotherapeutics Inc • Biological products, (no disgnostic substances) • Massachusetts
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Exhibit 10.16.4 LOAN MODIFICATION AGREEMENT This Loan Modification Agreement (this "Loan Modification Agreement") is entered into as of January 25, 2004, by and between SILICON VALLEY BANK, a California-chartered bank, with its principal place of...Loan Modification Agreement • March 8th, 2004 • GTC Biotherapeutics Inc • Biological products, (no disgnostic substances)
Contract Type FiledMarch 8th, 2004 Company Industry
FIFTH AMENDMENT TOTerm Loan Agreement • March 27th, 1998 • Genzyme Transgenics Corp • Biological products, (no disgnostic substances) • Massachusetts
Contract Type FiledMarch 27th, 1998 Company Industry Jurisdiction
SECURITIES PURCHASE AGREEMENTSecurities Purchase Agreement • August 8th, 2005 • GTC Biotherapeutics Inc • Biological products, (no disgnostic substances) • New York
Contract Type FiledAugust 8th, 2005 Company Industry JurisdictionThis Securities Purchase Agreement (this “Agreement”) is dated as of August 8, 2005, among GTC Biotherapeutics, Inc., a Massachusetts corporation (the “Company”), and each purchaser identified on the signature pages hereto (each, including its successors and permitted assigns, a “Purchaser” and collectively the “Purchasers”).
EXHIBIT 10.4 CONFIDENTIAL MATERIALS OMITTED AND FILED SEPARATELY WITH THE SECURITIES AND EXCHANGE COMMISSION. ASTERISKS DENOTE SUCH OMISSIONS. AMENDED AND RESTATED COLLABORATION AGREEMENTCollaboration Agreement • November 13th, 2001 • Genzyme Transgenics Corp • Biological products, (no disgnostic substances) • Massachusetts
Contract Type FiledNovember 13th, 2001 Company Industry Jurisdiction
REVO BIOLOGICS, INC. FORM OF [DIRECTOR][OFFICER] INDEMNIFICATION AGREEMENTIndemnification Agreement • June 25th, 2014 • rEVO Biologics, Inc. • Biological products, (no disgnostic substances) • Delaware
Contract Type FiledJune 25th, 2014 Company Industry JurisdictionThis Indemnification Agreement (“Agreement”) is made as of by and between rEVO Biologics, Inc., a Delaware corporation (the “Company”), and (“Indemnitee”).
CONFIDENTIAL GTC Biotherapeutics, Inc.GTC Biotherapeutics Inc • February 11th, 2008 • Biological products, (no disgnostic substances) • New York
Company FiledFebruary 11th, 2008 Industry Jurisdiction
Exhibit 10.1 SEPARATION AGREEMENT AND GENERAL RELEASE This Agreement dated as of May 16, 2001 is by and between Genzyme Transgenics Corporation ("GTC"), its predecessors, subsidiaries, successors, related and affiliated companies, assigns, officers,...Separation Agreement and General Release • August 7th, 2001 • Genzyme Transgenics Corp • Biological products, (no disgnostic substances) • Massachusetts
Contract Type FiledAugust 7th, 2001 Company Industry Jurisdiction
Exhibit 10.28.6 THIRD AMENDMENT TO CREDIT AGREEMENT AND AMENDMENT TO REVOLVING CREDIT NOTE AND TERM NOTE Reference is hereby made to that certain Credit Agreement dated as of December 28, 1998, as amended, by and between Genzyme Transgenics...Credit Agreement • March 22nd, 2002 • Genzyme Transgenics Corp • Biological products, (no disgnostic substances) • Massachusetts
Contract Type FiledMarch 22nd, 2002 Company Industry Jurisdiction
ARTICLE I INTERPRETATION AND APPLICATIONService Agreement • March 28th, 2003 • GTC Biotherapeutics Inc • Biological products, (no disgnostic substances) • Massachusetts
Contract Type FiledMarch 28th, 2003 Company Industry Jurisdiction
ARTICLE 1 EMPLOYMENT OF EXECUTIVEExecutive Employment Agreement • November 13th, 2001 • Genzyme Transgenics Corp • Biological products, (no disgnostic substances) • Massachusetts
Contract Type FiledNovember 13th, 2001 Company Industry Jurisdiction
FORM OF SECURITIES PURCHASE AGREEMENTForm of Securities Purchase Agreement • February 11th, 2008 • GTC Biotherapeutics Inc • Biological products, (no disgnostic substances) • New York
Contract Type FiledFebruary 11th, 2008 Company Industry JurisdictionThis Securities Purchase Agreement (this “Agreement”) is dated as of February 7, 2008, between GTC Biotherapeutics, Inc., a Massachusetts corporation (the “Company”), and each purchaser identified on the signature pages hereto (each, including its successors and assigns, a “Purchaser” and collectively the “Purchasers”).
GENZYME GENZYME TRANSGENICS CORP. TRANSGENICS 175 CROSSING BOULEVARD, SUITE 410 PO. BOX 9322 FRAMINGHAM, MA 01701-9322 TEL 508-620-9700 FAX 508-370-3797 MANAGEMENT AGREEMENT This Severance Agreement, dated as of June 14, 2000, is among Genzyme...Management Agreement • May 6th, 2003 • GTC Biotherapeutics Inc • Biological products, (no disgnostic substances) • Massachusetts
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EXHIBIT 10.29.2 THIS SECURITY HAS NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE "ACT"), OR APPLICABLE STATE SECURITIES LAWS AND MAY NOT BE TRANSFERRED OR OTHERWISE DISPOSED OF UNLESS IT HAS BEEN REGISTERED UNDER THE ACT AND...Genzyme Transgenics Corp • April 5th, 1999 • Biological products, (no disgnostic substances) • Massachusetts
Company FiledApril 5th, 1999 Industry JurisdictionTHIS SECURITY HAS NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE "ACT"), OR APPLICABLE STATE SECURITIES LAWS AND MAY NOT BE TRANSFERRED OR OTHERWISE DISPOSED OF UNLESS IT HAS BEEN REGISTERED UNDER THE ACT AND SUCH LAWS OR (1) REGISTRATION UNDER APPLICABLE STATE SECURITIES LAWS IS NOT REQUIRED AND (2) AN OPINION OF COUNSEL SATISFACTORY TO THE BORROWER IS FURNISHED TO THE BORROWER TO THE EFFECT THAT REGISTRATION UNDER THE ACT IS NOT REQUIRED.
GTC Biotherapeutics, Inc. and , as Trustee INDENTURE Dated as of ,GTC Biotherapeutics Inc • October 21st, 2005 • Biological products, (no disgnostic substances) • Massachusetts
Company FiledOctober 21st, 2005 Industry JurisdictionINDENTURE, dated as of , , by and between GTC Biotherapeutics, Inc., a Massachusetts corporation, as Issuer (the “Company”), and , a organized under the laws of , as Trustee (the “Trustee”).
CONFIDENTIAL TREATMENT GTC Biotherapeutics, Inc. has requested that the marked portions of this document be accorded confidential treatment pursuant to Rule 24b-2 promulgated under the Securities Exchange Act FIRST AMENDMENT TO AGREEMENT This is the...Agreement • March 8th, 2004 • GTC Biotherapeutics Inc • Biological products, (no disgnostic substances)
Contract Type FiledMarch 8th, 2004 Company Industry