RECITALSLease Agreement • October 17th, 2005 • Altus Pharmaceuticals Inc. • Washington
Exhibit 10.6 NON-QUALIFIED STOCK OPTION AGREEMENT ALTUS PHARMACEUTICALS INC. AGREEMENT made as of the AGREEMENT DATE, between Altus Pharmaceuticals Inc. (the "Company"), a Delaware corporation having a principal place of business in Cambridge,...Non-Qualified Stock Option Agreement • October 17th, 2005 • Altus Pharmaceuticals Inc. • Delaware
EXHIBIT 10.26 PURCHASE AGREEMENT Agreement made as of the 10 day of October, 2005 (the "Agreement Date"), between Altus Pharmaceuticals Inc., a Delaware corporation with its principal office at 125 Sidney Street, Cambridge, MA 01239, USA ("ALTUS"),...Purchase Agreement • January 11th, 2006 • Altus Pharmaceuticals Inc. • Biological products, (no disgnostic substances) • New York
Exhibit 10.5 INCENTIVE STOCK OPTION AGREEMENT ALTUS PHARMACEUTICALS INC. AGREEMENT made as of the AGREEMENT DATE, between Altus Pharmaceuticals Inc. (the "Company"), a Delaware corporation having a principal place of business in Cambridge,...Incentive Stock Option Agreement • October 17th, 2005 • Altus Pharmaceuticals Inc. • Delaware
Exhibit 10.18 November 24, 2004 Mr. Peter L. Lanciano 66 White Wood Road Milford, MA 01757 Dear Peter: The purpose of this letter agreement ("Agreement") is to set forth the terms of your separation from Altus Pharmaceuticals Inc. (the "Company"). The...Letter Agreement • November 30th, 2005 • Altus Pharmaceuticals Inc. • Biological products, (no disgnostic substances) • Massachusetts
Exhibit 4.7 NEITHER THIS WARRANT NOR THE SECURITIES ISSUABLE UPON EXERCISE OF THIS WARRANT HAVE BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED. NO SALE OR DISPOSITION MAY BE EFFECTED EXCEPT IN COMPLIANCE WITH RULE 144 UNDER SAID ACT OR...Altus Pharmaceuticals Inc. • October 17th, 2005 • Connecticut
SUBLEASESublease Agreement • October 17th, 2005 • Altus Pharmaceuticals Inc. • Massachusetts
SUBLEASEAltus Pharmaceuticals Inc. • October 17th, 2005
Exhibit 4.8 THIS WARRANT, AND THE SECURITIES ISSUABLE HEREUNDER, HAVE NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED, (THE "ACT') OR THE APPLICABLE SECURITIES LAWS OF ANY STATE, AND MAY NOT BE SOLD, TRANSFERRED OR ASSIGNED UNLESS...Altus Pharmaceuticals Inc. • October 17th, 2005 • Massachusetts
Exhibit 1.1 ALTUS PHARMACEUTICALS INC. (a Delaware corporation) 6,000,000 Shares of Common Stock PURCHASE AGREEMENT Dated: -, 2006 ALTUS PHARMACEUTICALS INC. (a Delaware corporation) 6,000,000 Shares of Common Stock (Par Value $.01 Per Share) PURCHASE...Altus Pharmaceuticals Inc. • January 11th, 2006 • Biological products, (no disgnostic substances) • New York
RecitalsSale Agreement • October 17th, 2005 • Altus Pharmaceuticals Inc. • Delaware
andStrategic Alliance Agreement • January 23rd, 2006 • Altus Pharmaceuticals Inc. • Biological products, (no disgnostic substances) • Massachusetts
Exhibit 10.13 TECHNOLOGY LICENSE AGREEMENT Agreement made as of the 1st day of February, 1999 (the "Effective Date"), between VERTEX PHARMACEUTICALS INCORPORATED, a Massachusetts corporation (together with its Affiliates, "Vertex"), and ALTUS...Technology License Agreement • January 11th, 2006 • Altus Pharmaceuticals Inc. • Biological products, (no disgnostic substances) • Massachusetts
. . Exhibit 10.21 LEASE FOR 125 SIDNEY STREET PROPERTY 1. PARTIES Rizika Realty Trust (whose mailing address is: 36 Edgehill Road, Brookline, MA 02445), the LESSOR, which expression shall include his heirs, successors, and assigns where the context so...Altus Pharmaceuticals Inc. • October 17th, 2005
RECITALSManufacturing and Supply Agreement • February 6th, 2007 • Altus Pharmaceuticals Inc. • Biological products, (no disgnostic substances) • England and Wales
Recitals:Stockholders' Voting Agreement • November 30th, 2005 • Altus Pharmaceuticals Inc. • Biological products, (no disgnostic substances) • Delaware
MASTER SECURITY AGREEMENT NO. 4081067 Dated as of AUGUST 19, 2004 ("AGREEMENT")Master Security Agreement • October 17th, 2005 • Altus Pharmaceuticals Inc. • Virginia
RECITALSIndemnification Agreement • November 30th, 2005 • Altus Pharmaceuticals Inc. • Biological products, (no disgnostic substances) • Delaware
RecitalsInvestor Rights Agreement • October 17th, 2005 • Altus Pharmaceuticals Inc. • Delaware
PROMISSORY NOTEAltus Pharmaceuticals Inc. • October 17th, 2005
Exhibit 10.2 ALTUS BIOLOGICS INC. 1993 STOCK OPTION PLAN INCENTIVE STOCK OPTION AGREEMENT This Stock Option Agreement sets forth the terms and conditions of an Option granted pursuant to the provisions of the 1993 Stock Option Plan (as from time tot...Incentive Stock Option Agreement • October 17th, 2005 • Altus Pharmaceuticals Inc.
BETWEENAnd Marketing Agreement • January 11th, 2006 • Altus Pharmaceuticals Inc. • Biological products, (no disgnostic substances) • Massachusetts
SEVERANCE AND CHANGE IN CONTROL AGREEMENTSeverance and Change in Control Agreement • May 5th, 2009 • Altus Pharmaceuticals Inc. • Biological products, (no disgnostic substances) • Massachusetts
This Agreement (the “Agreement”) is entered into as of the 30th day of April, 2009 by and between Altus Pharmaceuticals Inc., a Delaware corporation (the “Company”), and Thomas J. Phair, Jr. (the “Executive”).
Exhibit 10.8 MASTER LEASE AGREEMENT dated as of May 21, 2002, ("Agreement") THIS AGREEMENT is between GENERAL ELECTRIC CAPITAL CORPORATION (together with its successors and assigns, if any, "LESSOR") and ALTUS BIOLOGICS INC. ("LESSEE"). Lessor has an...Master Lease Agreement • October 17th, 2005 • Altus Pharmaceuticals Inc.
andStrategic Alliance Agreement • November 2nd, 2005 • Altus Pharmaceuticals Inc. • Biological products, (no disgnostic substances) • Massachusetts
EXHIBIT 10.6.1 ALTUS PHARMACEUTICALS INC. NON-QUALIFIED STOCK OPTION AGREEMENT AGREEMENT made as of the <>, between Altus Pharmaceuticals Inc. (the "Company"), a Delaware corporation having a principal place of business in Cambridge, Massachusetts,...Non-Qualified Stock Option Agreement • January 11th, 2006 • Altus Pharmaceuticals Inc. • Biological products, (no disgnostic substances) • Delaware
WITNESSETH:Cooperative Development Agreement • December 27th, 2005 • Altus Pharmaceuticals Inc. • Biological products, (no disgnostic substances)
Exhibit 10.3 ALTUS BIOLOGICS INC. 1993 STOCK OPTION PLAN NON-QUALIFIED STOCK OPTION AGREEMENT This Stock Option Agreement sets forth the terms and conditions of an Option granted pursuant to the provisions of the 1993 Stock Option Plan (as from time...Qualified Stock Option Agreement • October 17th, 2005 • Altus Pharmaceuticals Inc.
WITNESSETH:Cooperative Development Agreement • January 23rd, 2006 • Altus Pharmaceuticals Inc. • Biological products, (no disgnostic substances)
ARTICLE I VOTING OF SHARESVoting Standstill Agreement • October 17th, 2005 • Altus Pharmaceuticals Inc. • Delaware
Altus Pharmaceuticals Inc. February 4, 2008Letter Agreement • March 11th, 2008 • Altus Pharmaceuticals Inc. • Biological products, (no disgnostic substances) • Massachusetts
The purpose of this letter agreement (the “Agreement”) is to set forth the terms of your resignation from Altus Pharmaceuticals Inc. (the “Company”). Payment of the Separation Pay described below is contingent on your agreement to and compliance with the terms of this Agreement. Neither this offer to you nor the Company’s entering into this Agreement shall constitute an admission by the Company.
LICENSE AGREEMENT by and between ALTUS PHARMACEUTICALS INC. and CYSTIC FIBROSIS FOUNDATION THERAPEUTICS, INC. DATED FEBRUARY 20, 2009 Portions of this Exhibit are omitted and have been filed separately with the Secretary of the Commission pursuant to...License Agreement • May 11th, 2009 • Altus Pharmaceuticals Inc. • Biological products, (no disgnostic substances) • Massachusetts
This License Agreement (this “Agreement”), is made as of February 20, 2009 (the “Effective Date”), by and between Altus Pharmaceuticals Inc., a Delaware corporation (“Altus”), and Cystic Fibrosis Foundation Therapeutics, Inc., a Maryland corporation (“CFFT”) and collectively, with Altus, the “Parties,” and each a “Party”).
Second Amendment to Drug Product Production and Clinical Supply AgreementSupply Agreement • May 7th, 2008 • Altus Pharmaceuticals Inc. • Biological products, (no disgnostic substances)
This Second Amendment (the “Second Amendment”) is entered into and effective as of March 12, 2008 (the “Second Amendment Date”) for the purpose of amending that certain Drug Product Production and Clinical Supply Agreement dated August 15, 2006 by and between Altus Pharmaceuticals Inc., a Delaware corporation (“Altus”), and Althea Technologies, Inc., a Delaware corporation (“Althea”), as amended by that certain First Amendment to Drug Product Production and Clinical Supply Agreement dated June 25, 2007 (collectively, the “Agreement”). Capitalized terms used but not otherwise defined herein shall have the meanings provided in the Agreement.
TERMINATION AND TRANSITION AMENDMENT TO THE COLLABORATION AND LICENSE AGREEMENTCollaboration and License Agreement • March 11th, 2008 • Altus Pharmaceuticals Inc. • Biological products, (no disgnostic substances)
THIS Amendment (the “Amendment”) to the Collaboration and License Agreement by and between Altus Pharmaceuticals, Inc. (“Altus”) and Genentech, Inc. (“Genentech”) dated December 19, 2006 (the “Agreement”) is made and entered into by Altus and Genentech effective as of December 19, 2007 (the “Amendment Effective Date”). Altus and Genentech may each be referred to as a “Party” or together, the “Parties”.
WITNESSETHCooperative Development Agreement • May 11th, 2007 • Altus Pharmaceuticals Inc. • Biological products, (no disgnostic substances)
