Common use of 1Notices Clause in Contracts

1Notices. All notices, requests, demands, consents and communications necessary or required under this Agreement shall be delivered by hand or sent by registered or certified mail, return receipt requested, by overnight prepaid courier or by e-mail to: If to Buyer, or following Closing, to the Company: Rhythm Pharmaceuticals Netherlands B.V. c/o Rhythm Pharmaceuticals, Inc. 000 Xxxxxxxx Xxxxxx, Xxxxx 0000 Xxxxxx, XX 00000 Attention: Xxx Xxxxxxxx Telephone: 000-000-0000 Email: xxxxxxxxx@xxxxxxxx.xxx with a copy (which shall not constitute notice) to: Xxxxxx & Xxxxxxx LLP 000 Xxxxxxxxx Xxxxxx, 00xx Xxxxx Boston, Massachusetts 02116 Attention: Xxxxx Xxxxxxxxx; Xxxxxx Ring Telephone: (000) 000-0000 Email: xxxxx.xxxxxxxxx@xx.xxx; xxxxxx.xxxx@xx.xxx If to Seller Representative: Thudaumot Holding B.V. Omval 84 1096 HW Amsterdam The Netherlands Attention: Xxxxxxxx van der Xxxxx Email: x.xxxxxxxxxxx@xxxxxxxx.xx with a copy (which shall not constitute notice) to: Xxxxx & Xxxxx LLP Xxxxxxxxxx 00, 0000 XX Xxxxxxxxx The Netherlands Attention: Xxxxxxxxxx xx Xxxxx, Xxxxxx Xxxxxxxx Telephone: +00 (0) 00 000 0000 Email: Xxxxxxxxxx.xxXxxxx@XxxxxXxxxx.xxx; Xxxxxx.Xxxxxxxx@XxxxxXxxxx.xxx ​ ​ ​ If to any Seller: Such address listed on the Company’s books and records. All such notices, requests, demands, consents and other communications shall be deemed to have been duly given or sent three (3) days following the date on which mailed, or one (1) day following the date mailed if sent by overnight courier, or on the date on which delivered by hand or by email or other electronic transmission, as the case may be, and addressed as aforesaid. Any notice to be given to any Seller hereunder shall be given to Seller Representative or, if for any reason there ceases to be a Seller Representative, to each Seller.

1Notices. All notices, requests, demands, consents and communications necessary notices or required under this Agreement shall be delivered by hand or sent by registered or certified mail, return receipt requested, by overnight prepaid courier or by e-mail to: If to Buyer, or following Closing, to the Company: Rhythm Pharmaceuticals Netherlands B.V. c/o Rhythm Pharmaceuticals, Inc. 000 Xxxxxxxx Xxxxxx, Xxxxx 0000 Xxxxxx, XX 00000 Attention: Xxx Xxxxxxxx Telephone: 000-000-0000 Email: xxxxxxxxx@xxxxxxxx.xxx with a copy (which shall not constitute notice) to: Xxxxxx & Xxxxxxx LLP 000 Xxxxxxxxx Xxxxxx, 00xx Xxxxx Boston, Massachusetts 02116 Attention: Xxxxx Xxxxxxxxx; Xxxxxx Ring Telephone: (000) 000-0000 Email: xxxxx.xxxxxxxxx@xx.xxx; xxxxxx.xxxx@xx.xxx If to Seller Representative: Thudaumot Holding B.V. Omval 84 1096 HW Amsterdam The Netherlands Attention: Xxxxxxxx van der Xxxxx Email: x.xxxxxxxxxxx@xxxxxxxx.xx with a copy (which shall not constitute notice) to: Xxxxx & Xxxxx LLP Xxxxxxxxxx 00, 0000 XX Xxxxxxxxx The Netherlands Attention: Xxxxxxxxxx xx Xxxxx, Xxxxxx Xxxxxxxx Telephone: +00 (0) 00 000 0000 Email: Xxxxxxxxxx.xxXxxxx@XxxxxXxxxx.xxx; Xxxxxx.Xxxxxxxx@XxxxxXxxxx.xxx ​ ​ ​ If to any Seller: Such address listed on the Company’s books and records. All such notices, requests, demands, consents and other communications hereunder shall be deemed to have been duly given or sent three and made if in writing and (3a) days following when served by personal delivery upon the date on which mailedParty for whom it is intended, or (b) one (1) day Business Day following the date mailed if day sent by overnight courier, return receipt requested, (c) when sent by facsimile, provided that the facsimile is promptly confirmed by telephone confirmation thereof, or (d) when sent by e-mail, provided, that a copy of the same notice or other communication sent by email is also sent by overnight courier, return receipt requested, on the date on which delivered same day as such email is sent, in each case to the Person at the address, facsimile number or e-mail address set forth below, or such other address, facsimile number or e-mail address as may be designated in writing hereafter, in the same manner, by hand or by email or other electronic transmissionsuch Person: To Seller Parent: Pfizer Inc. 000 X. 00xx Xxxxxx Xxx Xxxx, as the case may beXX 00000 Email: Attention: Executive Vice President and General Counsel with a copy to: Skadden, and addressed as aforesaid. Any notice to be given to any Seller hereunder shall be given to Seller Representative orArps, if for any reason there ceases to be Slate, Xxxxxxx & Xxxx LLP Xxxx Xxxxx Xxxxxx Xxx Xxxx, XX 00000 Email: xxxx.xxxxxxx@xxxxxxx.xxx; xxxxxxx.xxxxx@xxxxxxx.xxx Attention: Xxxx X. Xxxxxxx; Xxxxxxx X. Xxxxx To Purchaser: ICU Medical, Inc. 000 Xxxxx Xxxxxxxx Xxx Xxxxxxxx, XX 00000 Attention: General Counsel E-mail: xxxxxxxx@xxxxxx.xxx with a Seller Representativecopy to: Xxxxxx & Xxxxxxx LLP 000 Xxxx Xxxxxx Xxxxx, to each Seller.00xx Xxxxx Xxxxx Xxxx, XX 00000 Attention: Xxxxxxx Xxxx; Xxxxxx Xxxxxxxxxxx; Xxxxxx Xxxx E-mail: Xxxxxxx.Xxxx@xx.xxx; Xxxxxx.Xxxxxxxxxxx@xx.xxx; Xxxxxx.Xxxx@xx.xxx

1Notices. All notices, requestsdemands and requests which may be given or which are required to be given by either Party to the other, demandsand any exercise of a right of termination provided by this Agreement, consents and communications necessary or required under this Agreement shall be delivered in writing and shall be given by hand either: (a) personal delivery to the address below, as evidenced by written receipt therefor, whether or sent not actually received by registered or the person to whom addressed with a copy via email; (b) United States Postal Service first class mail, postage prepaid simultaneous with email delivery as provided below, upon confirmation from the recipient of the same (which shall include any response thereto), (c) certified mail, return receipt requested, addressed to the intended recipient at the address specified below, whether or not actually received by the person to whom addressed with a copy via email; or (d) by a nationally recognized overnight prepaid courier delivery service such as FedEx, addressed to such Party at the address specified below, whether or not actually received by e-mail the person to whom addressed with a copy via email. Such notices shall be deemed delivered on the date shown on the delivery receipt as the date of delivery, the date delivery was refused or the date the item was returned as undeliverable. For purposes of this Section 9.1 the addresses of the Parties for all notices are as follows (unless changed by similar notice in writing given by the particular person whose address is to be changed): If to Seller: Xxxxxxx Xxxxxxx, Esquire 000 Xxxxxxxx Xxxxxxxxxx, XX 00000 xxxxxxxx@xxxxxxx.xxx With a Copy to: Xxxxxx X. Xxxxxx, Esquire 000 Xxxxxxx Xxxxxx Farmingdale, NY 11735 xxx@xxxxxxxxx.xxx If to Buyer: Integra Housing LLC 00 Xxxxxxxxx Xxxxx Xxxxxx Xxxxxx, or following ClosingXX 00000 Attention:Xxxx Xxxxxxxx xxxxxxx@xxxxxxxxxxxxxx.xxx With a Copy to: X’Xxxxx, to the Company: Rhythm Pharmaceuticals Netherlands B.V. c/o Rhythm PharmaceuticalsXxxxx & Xxxxxxx, Inc. P.C. 000 Xxxxxxxx XxxxxxXxxxxxxxxx Xxxx, Xxxxx 0000 XxxxxxXxxxxxxxxx, XX 00000 Attention: Xxx Xxxxxxxx Telephone: 000-000-0000 Email: xxxxxxxxx@xxxxxxxx.xxx with a copy (which shall not constitute notice) to: Xxxxxx & Xxxxxxx LLP 000 Xxxxxxxxx XxxxxxXxxxxxx, 00xx Xxxxx Boston, Massachusetts 02116 Attention: Xxxxx Xxxxxxxxx; Xxxxxx Ring Telephone: (000) 000-0000 Email: xxxxx.xxxxxxxxx@xx.xxx; xxxxxx.xxxx@xx.xxx If to Seller Representative: Thudaumot Holding B.V. Omval 84 1096 HW Amsterdam The Netherlands Attention: Xxxxxxxx van der Xxxxx Email: x.xxxxxxxxxxx@xxxxxxxx.xx with a copy (which shall not constitute notice) to: Xxxxx & Xxxxx LLP Xxxxxxxxxx 00, 0000 XX Xxxxxxxxx The Netherlands Attention: Xxxxxxxxxx xx Xxxxx, Xxxxxx Xxxxxxxx Telephone: +00 (0) 00 000 0000 Email: Xxxxxxxxxx.xxXxxxx@XxxxxXxxxx.xxx; Xxxxxx.Xxxxxxxx@XxxxxXxxxx.xxx ​ ​ ​ If to any Seller: Such address listed on the Company’s books and recordsEsq. All such notices, requests, demands, consents and other communications shall be deemed to have been duly given or sent three (3) days following the date on which mailed, or one (1) day following the date mailed if sent by overnight courier, or on the date on which delivered by hand or by email or other electronic transmission, as the case may be, and addressed as aforesaid. Any notice to be given to any Seller hereunder shall be given to Seller Representative or, if for any reason there ceases to be a Seller Representative, to each Seller.xxxxxxxx@xxx-xxx.xxx

1Notices. All notices, requests, demands, consents notices and other communications necessary or required under this Agreement shall be delivered in writing and shall be by hand email with PDF attachment, courier service or sent personal delivery to the following addresses, or to such other addresses as shall be designated from time to time by registered or certified mail, return receipt requested, by overnight prepaid courier or by e-mail toa party hereto in accordance with this Section 8.1: If to Buyer, or following Closingthe Seller, to the Companyit at: Rhythm Pharmaceuticals Netherlands B.V. c/o Rhythm PharmaceuticalsPTC Therapeutics, Inc. 000 Xxxxxxxx Xxxxxxxxx Xxxxx Xxxxx Xxxxxxxxxx, Xxx Xxxxxx 00000 Attention: Legal Department Email: [**] With a copy to: Xxxxxx Xxxxxx Xxxxxxxxx Xxxx and Xxxx LLP 00 Xxxxx Xxxxxx Xxxxxx, Xxxxxxxxxxxxx 00000 Attention: Xxxxxx X. Xxxxxxx and Xxxxxx X. Xxxxxxx, Xx. Email: xxxxxx.xxxxxxx@xxxxxxxxxx.xxx; xxxxxx.xxxxxxx@xxxxxxxxxx.xxx If to the Buyer, to it at: RP Management, LLC 000 X. 00xx Xxxxxx, Xxxxx 0000 XxxxxxXxx Xxxx, XX Xxx Xxxx 00000 Attention: Xxx Xxxxxxxx Telephone: 000-000-0000 General Counsel Email: xxxxxxxxx@xxxxxxxx.xxx with [**] With a copy (which shall not constitute notice) to: Xxxxxx & Xxxxxxx Procter LLP 000 Xxxxxxxxx Xxxxxxxx Xxxxxx Xxxxxx, 00xx Xxxxx Boston, Massachusetts 02116 Xxxxxxxxxxxxx 00000 ​ Attention: Xxxxx Xxxxxxxxx; Xxxxxx Ring Telephone: (000) 000-0000 X. Xxxxxxxx and Xxxxxxxxxx Xxxxxxx Email: xxxxx.xxxxxxxxx@xx.xxxxxxxxxxxx@xxxxxxxxxx.xxx; xxxxxx.xxxx@xx.xxx If to Seller Representative: Thudaumot Holding B.V. Omval 84 1096 HW Amsterdam The Netherlands Attention: Xxxxxxxx van der Xxxxx Email: x.xxxxxxxxxxx@xxxxxxxx.xx with a copy (which shall not constitute notice) to: Xxxxx & Xxxxx LLP Xxxxxxxxxx 00, 0000 XX Xxxxxxxxx The Netherlands Attention: Xxxxxxxxxx xx Xxxxx, Xxxxxx Xxxxxxxx Telephone: +00 (0) 00 000 0000 Email: Xxxxxxxxxx.xxXxxxx@XxxxxXxxxx.xxx; Xxxxxx.Xxxxxxxx@XxxxxXxxxx.xxx ​ ​ ​ If to any Seller: Such address listed on the Company’s books xxxxxxxx@xxxxxxxxxx.xxx All notices and records. All such notices, requests, demands, consents and other communications under this Agreement shall be deemed to have been duly given (i) when delivered by hand, if personally delivered, (ii) when received by a recipient, if sent by e mail with delivery confirmation thereof, (iii) when sent, if sent by facsimile, with an acknowledgement of sending being produced by the sending facsimile machine or sent three (3iv) days following the date on which mailed, or one (1) day Business Day following sending within the date mailed if sent United States by overnight courier, or on the date on which delivered by hand or by email or other electronic transmission, as the case may be, and addressed as aforesaid. Any notice to be given to any Seller hereunder shall be given to Seller Representative or, if for any reason there ceases to be a Seller Representative, to each Sellerdelivery via commercial one- (1-)day overnight courier service.

1Notices. All notices, requests, demands, consents and communications necessary Any notice required or required permitted to be given under this Agreement shall be in writing and personally delivered by hand or sent by United States mail, registered or certified mail, postage prepaid, return receipt requested, by overnight prepaid courier or by e-mail toelectronic facsimile transmission (followed by a copy mailed or delivered as otherwise provided herein), or sent by Federal Express or similar nationally recognized overnight courier service, and addressed as follows, and shall be deemed to have been given upon the date of delivery (or refusal to accept delivery) at the address specified below as indicated on the return receipt or air bxxx, or on the date of facsimile transmission if delivered in such manner: If to BuyerSellers: Vista Ridge Plaza, or following Closing, to the Company: Rhythm Pharmaceuticals Netherlands B.V. Ltd. c/o Rhythm Pharmaceuticals, Inc. 000 Xxxxxxxx Xxxxxx, Xxxxx 0000 XxxxxxDal Mac Investments 100 X. Xxxxxx Xxxxxx Xxxx Xxxxxxxxxx, XX 00000 Attention: Xxx Xxxxxxxx TelephoneBxxx XxXxxxxx Fax No.: 000900-000-0000 EmailVista Ridge Plaza II, Ltd. c/o Dal Mac Investments 100 X. Xxxxxx Xxxxxx Xxxx Xxxxxxxxxx, XX 00000 Attention: xxxxxxxxx@xxxxxxxx.xxx Bxxx XxXxxxxx Fax No.: 900-000-0000 Vista Ridge Shops, Inc. c/o Dal Mac Investments 100 X. Xxxxxx Xxxxxx Xxxx Xxxxxxxxxx, XX 00000 Attention: Bxxx XxXxxxxx Fax No.: 900-000-0000 with a copy (which shall not constitute notice) to: :Dxxxxxx, Xxxxxxx & Cxxxxxx 1000 Xxx Xxxxxx & Xxxxxxx LLP 000 Xxxxxxxxx 00xx Xxxxx Xxxxxx, 00xx Xxxxx Boston, Massachusetts 02116 Attention: Xxxxx Xxxxxxxxx; Xxxxxx Ring TelephoneMxxx Xxx Xxxx, Esq. Fax No.: (000) 000-0000 Email: xxxxx.xxxxxxxxx@xx.xxx; xxxxxx.xxxx@xx.xxx If to Seller RepresentativeBuyer: Thudaumot Holding B.V. Omval 84 1096 HW Amsterdam The Netherlands AttentionPRICE/BAYBROOK, LTD. 100 Xxxxx Xxxxxxx Xxxxxx Xxxxxx Xxxxx Xxx Xxxxxxx, XX 00000 Attn.: Xxxxxxxx van der Xxxxx EmailJxxxxx Xxxxxxxxxx Fax No.: x.xxxxxxxxxxx@xxxxxxxx.xx (000) 000-0000 with a copy to:Gxxxxx, Dxxx & Cxxxxxxx LLP 300 Xxxxx Xxxxx Xxxxxx Xxx Xxxxxxx, Xxxxxxxxxx 00000 Attn: Wxxxxxx X. Xxxxxxx, Esq. Fax No.: (which shall not constitute notice000) to: Xxxxx & Xxxxx LLP Xxxxxxxxxx 00, 000-0000 XX Xxxxxxxxx The Netherlands Attention: Xxxxxxxxxx xx Xxxxx, Xxxxxx Xxxxxxxx Telephone: +00 (0) 00 000 0000 Email: Xxxxxxxxxx.xxXxxxx@XxxxxXxxxx.xxx; Xxxxxx.Xxxxxxxx@XxxxxXxxxx.xxx ​ ​ ​ If to any SellerEscrow Holder: Such address listed on the Company’s books and records. All such noticesWeststar Title Company 10000 Xxxxxxx Xxxx Xxxxx 000 Xxxxxx, requests, demands, consents and other communications shall be deemed to have been duly given or sent three (3) days following the date on which mailed, or one (1) day following the date mailed if sent by overnight courier, or on the date on which delivered by hand or by email or other electronic transmission, as the case may be, and addressed as aforesaid. Any notice to be given to any Seller hereunder shall be given to Seller Representative or, if for any reason there ceases to be a Seller Representative, to each SellerXX 00000 Attn: Nxxxx Xxxxxxxxx Fax No.: 900-000-0000

1Notices. All (a)All notices, requests, demands, requests or consents and communications necessary provided for or required permitted to be given under this Agreement shall will be delivered in writing and will be given (a) by hand or sent by registered or certified depositing such writing in the United States mail, addressed to the recipient, postage paid and certified with return receipt requested, (b) by depositing such writing with a reputable overnight prepaid courier for next day delivery or (c) by delivering such writing to the recipient in person, by courier or by e-mail toemail transmission. A notice, request or consent given under this Agreement will be effective on receipt by the Person to receive it except that a notice, request or consent given by email transmission will be effective when sent. All notices, requests and consents to be sent to the Parties will be sent to or made at the addresses given for that Party as follows: If to BuyerContributor, or following Closing, to the Companyto: Rhythm Pharmaceuticals Netherlands B.V. c/o Rhythm Pharmaceuticals, Inc. 000 Xxxxxxxx XxxxxxHOBO Renewable Diesel LLC 0000 Xxxx Xxx Xxxx., Xxxxx 0000 XxxxxxXxxxxxx, XX Xxxxx 00000 Attention: Xxx Xxxxxxxx Telephone: 000-000-0000 Xxxxx Xxxxx Email: xxxxxxxxx@xxxxxxxx.xxx with xxxxxx@xxxxxx.xxx With a copy to (which shall not constitute notice) ): ​ King & Spalding LLP 0000 Xxxxxxxxx Xxxxxx, Xxxxx 0000 Xxxxxxx, Xxxxx 00000 Attention: Xxxxxx X. Xxxxxx Exhibit B - 31 ​ Email: xxxxxxx@xxxxx.xxx If to Project HoldCo, to: ​ [insert legal name of Project HoldCo] 0000 Xxxx Xxx Xxxx, Xxxxx 0000 Xxxxxxx, XX 00000 Attention: [●] Email: [●] With a copy to: ​ Evolve Transition Infrastructure LP c/o Stonepeak Infrastructure Partners 000 Xxxxxx & Xxxxxxx LLP Xxxxxx, Suite 6290 Houston, Texas 77002 Attn: Xxxx Xxxxxx Email: Xxxxxx@xxxxxxxxxxxxxxxxx.xxx ​ With an additional copy to: ​ Stonepeak Partners LP 55 Xxxxxx Yards 000 Xxxxxxxxx X. 00xx Xxxxxx, 00xx Xxxxx BostonXxx Xxxx, Massachusetts 02116 Xxx Xxxx 00000 Attention: Xxxxx Xxxxxxxxx; Xxxxxx Ring Telephone: (000) 000-0000 Xxxxxxx Xxxxxxx and Xxxxxxxx Xxxxxxxx Email: xxxxx.xxxxxxxxx@xx.xxxxxxxxxx@xxxxxxxxxxxxxxxxx.xxx; xxxxxx.xxxx@xx.xxx If xxxxxxxxxxxxxxxxxx@xxxxxxxxxxxxxxxxx.xxx With an additional copy to Seller Representative: Thudaumot Holding B.V. Omval 84 1096 HW Amsterdam The Netherlands Attention: Xxxxxxxx van der Xxxxx Email: x.xxxxxxxxxxx@xxxxxxxx.xx with a copy (which shall not constitute notice) to): ​ Sidley Austin LLP 0000 Xxxxxxxxx Xx., Xxxxx 0000 Xxxxxxx, Xxxxx 00000 Attention: Xxxxx & Xxxxx LLP Xxxxxxxxxx 00, 0000 XX Xxxxxxxxx The Netherlands Attention: Xxxxxxxxxx xx Xxxxx, Xxxxxx X. Xxxxxxxx Telephone: +00 (0) 00 000 0000 Email: Xxxxxxxxxx.xxXxxxx@XxxxxXxxxx.xxx; Xxxxxx.Xxxxxxxx@XxxxxXxxxx.xxx ​ ​ ​ If to any Seller: Such address listed on the Company’s books and records. All such notices, requests, demands, consents and other communications shall be deemed to have been duly given or sent three (3) days following the date on which mailed, or one (1) day following the date mailed if sent by overnight courier, or on the date on which delivered by hand or by email or other electronic transmission, as the case may be, and addressed as aforesaid. Any notice to be given to any Seller hereunder shall be given to Seller Representative or, if for any reason there ceases to be a Seller Representative, to each Seller.xxxxxxxxx@xxxxxx.xxx

1Notices. All notices, requests, demands, consents notices and other communications necessary or required under this Agreement shall must be in writing and are deemed duly delivered when: (a) delivered, if delivered personally or by hand or nationally recognized overnight courier service (costs prepaid); (b) sent by facsimile or by email with confirmation of receipt (or, the first Business Day following such transmission if the date of transmission is not a Business Day); or (c) received or rejected by the addressee, if sent by United States of America certified or registered or certified mail, return receipt requested; in each case to the following addresses or facsimile numbers and marked to the attention of the individual (by name or title) designated below (or to such other address, facsimile number or individual as a party may designate by overnight prepaid courier or by e-mail to: notice to the other party): If to Buyer, or following Closing, to the CompanySeller: Rhythm Pharmaceuticals Netherlands B.V. c/o Rhythm PharmaceuticalsAchaogen, Inc. Xxx Xxxxx Xxxxx, Xxxxx 000 Xxxxxxxx Xxxxx Xxx Xxxxxxxxx, Xxxxxxxxxx 00000 Attn: Xxxxx Xxxx, Chief Executive Officer Email: xxxxx@xxxxxxxx.xxx Meru, LLC 0000 Xxxxxxxxx Xxxxxx, XX, Xxxxx 0000 XxxxxxXxxxxxx, XX 00000 AttentionAttn: Xxx Xxxxxxxx Telephone: 000-000-0000 Xxxx Xxxxxxxx, Managing Partner Email: xxxxxxxxx@xxxxxxxx.xxx xxxx@xxxxxxxxx.xxx with a copy (which shall will not constitute notice) to: Xxxxx Lovells US LLP 1999 Avenue of the Stars, Xxxxx 0000 Xxx Xxxxxxx, Xxxxxxxxxx 00000 Attn: Xxxxxxx Xxxxx, Esquire Xxxx Xxxxx, Esquire Email: xxxx.xxxxx@xxxxxxxxxxxx.xxx xxxx.xxxxx@xxxxxxxxxxxx.xxx Exhibit 2.1 following the Closing, with a copy (which will not constitute notice) to: Akin Gump Xxxxxxx Xxxxx & Xxxx LLP Xxx Xxxxxx Xxxx Xxx Xxxx, XX 00000 Attn: Xxxx Xxxxx, Esq. Email: xxxxxx@xxxxxxxx.xxx If to the Purchaser: Cipla USA Inc. c/o Cipla Ltd. Cipla House, Peninsula Business Park Xxxxxxxxxx Xxxxx Xxxx, Xxxxx Xxxxx Xxxx Xxxxxx, Xxxxxxxxxxx 000000, Xxxxx Attn: A.S. Kumar, Esq., Global General Counsel Email: xx.xxxxx@xxxxx.xxx xxxxxxxxxxx@xxxxx.xxx with a copy (which will not constitute notice) to: Xxxxxx Xxxx & Xxxxxxx Xxxxxx LLP 000 Xxxxxxxxx Xxxx Xxxxxx, 00xx Xxxxx BostonXxx Xxxx, Massachusetts 02116 AttentionXxx Xxxx 00000 Attn: Xxxxx Xxxxxxxxx; Xxxxxx Ring Telephone: (000) 000-0000 Xxxxxxx, Esq. Email: xxxxx.xxxxxxxxx@xx.xxx; xxxxxx.xxxx@xx.xxx If to Seller Representative: Thudaumot Holding B.V. Omval 84 1096 HW Amsterdam The Netherlands Attention: Xxxxxxxx van der Xxxxx Email: x.xxxxxxxxxxx@xxxxxxxx.xx with a copy (which shall not constitute notice) to: Xxxxx & Xxxxx LLP Xxxxxxxxxx 00, 0000 XX Xxxxxxxxx The Netherlands Attention: Xxxxxxxxxx xx Xxxxx, Xxxxxx Xxxxxxxx Telephone: +00 (0) 00 000 0000 Email: Xxxxxxxxxx.xxXxxxx@XxxxxXxxxx.xxx; Xxxxxx.Xxxxxxxx@XxxxxXxxxx.xxx ​ ​ ​ If to any Seller: Such address listed on the Company’s books and records. All such notices, requests, demands, consents and other communications shall be deemed to have been duly given or sent three (3) days following the date on which mailed, or one (1) day following the date mailed if sent by overnight courier, or on the date on which delivered by hand or by email or other electronic transmission, as the case may be, and addressed as aforesaid. Any notice to be given to any Seller hereunder shall be given to Seller Representative or, if for any reason there ceases to be a Seller Representative, to each Seller.XXxxxxxx@XxxxxxXxxx.xxx

1Notices. All noticesExcept as permitted in Section 35.2 below, requestsany notice, demands, consents and communications necessary request or required under this Agreement other communication to be given by any party hereunder shall be delivered by hand or in writing and shall be sent by registered or certified mail, postage prepaid and return receipt requested, by overnight prepaid hand delivery or nationally recognized express courier or by e-mail to: If to Buyer, or following Closing, service to the Companyfollowing address: Rhythm Pharmaceuticals Netherlands B.V. To Tenant: BELLAGIO, LLC c/o Rhythm Pharmaceuticals, Inc. MGM Resorts International 0000 Xxxxx Xxxxxxx Xxxxxxxxx Xxxxx 000 Xxxxxxxx Xxxxxx, Xxxxx 0000 XxxxxxXxx Xxxxx, XX 00000 Attention: Xxx Xxxxxxxx TelephoneCorporate Legal With a copy to: 000-000-0000 (that shall not constitute notice) Email: xxxxxxxxx@xxxxxxxx.xxx with xxxxxxxxxxxx@xxxxxxxxxx.xxx With a copy to: (that shall not constitute notice) Xxxx, Gotshal & Xxxxxx, LLP 000 Xxxxx Xxxxxx Xxx Xxxx, XX 00000 Attention: Xxxxxxx Xxxxxx W. Xxxxxxx Xxxx Email: xxxxxxx.xxxxxx@xxxx.xxx xxxxxxx.xxxx@xxxx.xxx To Landlord: c/o Blackstone Real Estate Advisors L.P. 000 Xxxx Xxxxxx Xxx Xxxx, Xxx Xxxx 00000 Attention: Head, U.S. Asset Management Email: xxxxxxxxxxxxxxxxx@xxxxxxxxxx.xxx and c/o Blackstone Real Estate Advisors L.P. 000 Xxxx Xxxxxx Xxx Xxxx, Xxx Xxxx 00000 Attention: General Counsel Email: xxxxxxxxxxxxxxxxx@xxxxxxxxxx.xxx And with copy to (which shall not constitute notice) to: Xxxxxx ): Xxxxxxx Xxxxxxx & Xxxxxxx Xxxxxxxx LLP 000 Xxxxxxxxx XxxxxxXxxxxx Xxx Xxxx, 00xx Xxxxx Boston, Massachusetts 02116 Xxx Xxxx 00000 Attention: Xxxxx Xxxxxxxxx; Xxxxxx Ring Telephone: (000) 000-0000 Email: xxxxx.xxxxxxxxx@xx.xxx; xxxxxx.xxxx@xx.xxx If to Seller Representative: Thudaumot Holding B.V. Omval 84 1096 HW Amsterdam The Netherlands Attention: Xxxxxxxx van der Xxxxxxx Xxxxx Email: x.xxxxxxxxxxx@xxxxxxxx.xx with a copy (which shall not constitute notice) to: Xxxxx xxxxxx@xxxxxx.xxx and Xxxxxxx Xxxxxxx & Xxxxx Xxxxxxxx LLP Xxxxxxxxxx 00000 Xxxxxxxxx Xxxxxx Xxx Xxxx, 0000 XX Xxxxxxxxx The Netherlands Xxx Xxxx 00000 Attention: Xxxxxxxxxx xx Xxxxx, Xxxxxx Xxxxxxxx Telephone: +00 (0) 00 000 0000 Xxxx Xxxxxxxxx Email: Xxxxxxxxxx.xxXxxxx@XxxxxXxxxx.xxx; Xxxxxx.Xxxxxxxx@XxxxxXxxxx.xxx ​ ​ ​ If xxxxxxxxxx@xxxxxx.xxx or to any Seller: Such such other address listed on the Company’s books and recordsas either party may hereafter designate. All such notices, requests, demands, consents and other communications Notice shall be deemed to have been duly given or sent three (3) days following the date on which mailed, or one (1) day following the date mailed if sent by overnight courier, or on the date of delivery if such delivery is made on which delivered by hand a Business Day, or by email or other electronic transmissionif not, as on the case may befirst Business Day after delivery. If delivery is refused, and addressed as aforesaid. Any notice to be given to any Seller hereunder Notice shall be deemed to have been given to Seller Representative or, if for on the date delivery was first attempted. A confirmatory copy of any reason there ceases to such notice shall also be a Seller Representative, to each Sellersent by email.