Weight of evidence definition

Weight of evidence means a structured framework approach for evaluating and assigning the relative or proportional contributions or weightings to each of multiple lines of evidence influencing the qualitative or quantitative estimation of risk or hazard in a risk assessment.
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Weight of evidence means that all scientific data bearing on the classification of a chemical shall be considered together, including the results of valid in vitro tests, relevant animal data, and human experience such as epidemiological and clinical studies, and well-documented case reports and observations. See Appendix A, Chapter A.0.3 of the standard for a further discussion on how to use the weight of evidence for classification.
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Weight of evidence a term of art, means a description of the likelihood that a chemical is a human carcinogen based on evaluation of tumor data from human or animal studies and examination of relevant supporting information, including any of the following information:
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Examples of Weight of evidence in a sentence

  • Method: Weight of evidence Substance data, where relevant and available, are listed below:.

  • Relevant calculated ATE(s):ATE - Oral (mg/kg): >2000 Skin irritation and corrosivityResult: Not corrosive or irritant Method: Weight of evidenceEye irritation and corrosivityResult: Eye irritant 2 Method: Weight of evidence Substance data, where relevant and available, are listed below:.

  • Relevant calculated ATE(s):ATE - Oral (mg/kg): >2000 Eye irritation and corrosivityResult: Eye irritant 2 Method: Weight of evidence Substance data, where relevant and available, are listed below:.

  • Weight of evidence: a framework for the appraisal of the quality and relevance of evidence.

  • Relevant calculated ATE(s):ATE - Oral (mg/kg): >2000 Eye irritation and corrosivity Result: Eye irritant 2 Method: Weight of evidence Substance data, where relevant and available, are listed below:.

  • Mixture data: Relevant calculated ATE(s):ATE - Oral (mg/kg): >2000 Skin irritation and corrosivityResult: Not corrosive or irritant Method: Weight of evidenceEye irritation and corrosivityResult: Eye irritant 2 Method: Weight of evidence Substance data, where relevant and available, are listed below.

  • Enacted by Chapter 283, 2017 General Session 41-6a-516 Admissibility of chemical test results in actions for driving under the influence -- Weight of evidence.

  • Weight of evidence of possible human carcinogenic effects sufficient to derive a Tier II human cancer value shall include those possible human carcinogens for which there are, at a minimum, data sufficient for quantitative risk assessment, but for which data are inadequate for Tier I criterion development due to a tumor response of marginal statistical significance or inability to derive a strong dose-response relationship.

  • Mixture data: Relevant calculated ATE(s):ATE - Oral (mg/kg): >2000 Eye irritation and corrosivityResult: Eye irritant 2 Method: Weight of evidence Substance data, where relevant and available, are listed below.

  • Weight of evidence of potential human carcinogenic effects sufficient to derive a Tier I human cancer criterion (HCC) shall generally include human carcinogens, and probable human carcinogens and may include, on a case-by-case basis, possible human carcinogens if studies have been well-conducted albeit based on limited evidence, when compared to studies used in classifying human and probable human carcinogens.


More Definitions of Weight of evidence

Weight of evidence approach means that findings from a large number of studies, including from studies in freely available literature, some of which have contradicting findings, are weighed against each other. A large number of additional factors also need to be taken into account, such as those described in the "Guidance on the Application of the CLP Criteria" in accordance with point 3.6.2.2.4-6. The BfR has followed these requirements.
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Weight of evidence approach means that results from a large number of studies, including from studies in freely available literature, some of which have contradicting results, are weighed against each other. A large number of additional factors also need to be take into account, such as those described in the "Guidance on the Application of the CLP Criteria" in accordance with point 3.6.2.2.4-6. The BfR followed these stipulations, in particular in drawing up the addendum and the CLH dossier.
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Weight of evidence means an evaluation of the relevant scientific data conducted to determine the likelihood that a hazardous substance is a human carcinogen or causes noncancer adverse health effects, or both. The evaluation may include any of the following information in addition to toxicological bioassays:
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Weight of evidence means the measure of credible proof (i.e., facts) on one side of an issue against that of the other;
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Related to Weight of evidence

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  • the Statutes means the Companies Act and every other act (as may from time to time be amended) for the time being in force in Bermuda applying to or affecting the Company, the Memorandum of Association and/or these presents;

  • the 1993 Act means the Pension Schemes Act 1993; “the 1995 Act” means the Pensions Act 1995;

  • Insurance Requirements means all terms of any insurance policy required by this Agreement and all requirements of the issuer of any such policy and all orders, rules and regulations and any other requirements of the National Board of Fire Underwriters (or any other body exercising similar functions) binding upon Landlord, Tenant or the Leased Property.

  • Flood Insurance Regulations means (i) the National Flood Insurance Act of 1968 as now or hereafter in effect or any successor statute thereto, (ii) the Flood Disaster Protection Act of 1973 as now or hereafter in effect or any successor statue thereto, (iii) the National Flood Insurance Reform Act of 1994 (amending 42 USC 4001, et seq.), as the same may be amended or recodified from time to time, and (iv) the Flood Insurance Reform Act of 2004 and any regulations promulgated thereunder.

  • the 1990 Act means the Town and Country Planning Act 1990;

  • South Caucasus/Central and South Asian (SC/CASA) state means Armenia, Azerbaijan, Georgia, Kazakhstan, Kyrgyzstan, Pakistan, Tajikistan, Turkmenistan, or Uzbekistan.

  • Public right-of-way means only the area of real property in which the City has a dedicated or acquired right-of-way interest in the real property. It shall include the area on, below or above the present and future streets, alleys, avenues, roads, highways, parkways or boulevards dedicated or acquired as right-of-way. The term does not include the airwaves above a right-of-way with regard to wireless telecommunications or other non-wire telecommunications or broadcast service, easements obtained by utilities or private easements in platted subdivisions or tracts.

  • FAA Xxxx of Sale means the xxxx of sale for the Aircraft on AC Form 8050-2 executed by Manufacturer or an affiliate of Manufacturer in favor of Company and recorded with the FAA.

  • Indigenous Peoples Safeguards means the principles and requirements set forth in Chapter V, Appendix 3, and Appendix 4 (as applicable) of the SPS;

  • the State means the Karnataka State

  • Applicable Technical Requirements and Standards means those certain technical requirements and standards applicable to interconnections of generation and/or transmission facilities with the facilities of an Interconnected Transmission Owner or, as the case may be and to the extent applicable, of an Electric Distributor, as published by Transmission Provider in a PJM Manual provided, however, that, with respect to any generation facilities with maximum generating capacity of 2 MW or less (synchronous) or 5 MW or less (inverter-based) for which the Interconnection Customer executes a Construction Service Agreement or Interconnection Service Agreement on or after March 19, 2005, “Applicable Technical Requirements and Standards” shall refer to the “PJM Small Generator Interconnection Applicable Technical Requirements and Standards.” All Applicable Technical Requirements and Standards shall be publicly available through postings on Transmission Provider’s internet website.

  • Warranty Xxxx of Sale means the warranty (as to title) xxxx of sale covering the Aircraft executed by Manufacturer or an affiliate of Manufacturer in favor of Company and specifically referring to each Engine, as well as the Airframe, constituting a part of the Aircraft.

  • the 1991 Act means the Water Industry Act 1991(a);

  • Indigenous Peoples means social groups with a distinct social and cultural identity that makes them vulnerable to being disadvantaged in the development process, including the presence in varying degrees of the following characteristics: (i) a close attachment to ancestral territories and to the natural resources in these areas; (ii) self-identification and identification by others as members of a distinct cultural group; (iii) an indigenous language, often different from Pilipino, the Recipient’s national language; (iv) presence of customary social and political institutions; and (v) primarily subsistence-oriented production.

  • Federal Aviation Act means the sections of Title 49 of the United States Code relating to aviation, as amended and in effect from time to time, or any similar legislation of the United States of America enacted in substitution or replacement thereof.

  • South Caucasus/Central and South Asian (SC/CASA) state means Armenia, Azerbaijan, Georgia, Kazakhstan, Kyrgyzstan, Pakistan, Tajikistan, Turkmenistan, or Uzbekistan.

  • Environmental Insurance Policy means, with respect to any Mortgage Loan or the related Mortgaged Property or REO Property, any insurance policy covering pollution conditions and/or other environmental conditions that is maintained from time to time in respect of such Mortgage Loan, Mortgaged Property or REO Property, as the case may be, for the benefit of, among others, the Trustee on behalf of the Certificateholders.

  • Point of Sale means, for a Placement, the time at which an acquiror of Placement Shares entered into a contract, binding upon such acquiror, to acquire such Placement Shares.

  • Federal Clean Air Act means Chapter 85 (§ 7401 et seq.) of Title 42 of the United States Code.

  • Commonwealth Standard Grant Conditions means this document.

  • Nationwide Mortgage Licensing System and Registry means a mortgage licensing system developed and maintained by the conference of state bank supervisors and the American association of residential mortgage regulators for the licensing and registration of licensed mortgage loan originators.

  • Standard Methods for the Examination of Water and Wastewater means the most recent edition of Standard Methods for the Examination of Water and Wastewater published jointly by the American Public Health Association, the American Waterworks Association and the Water Environment Federation;

  • the 1992 Act means the Local Government Finance Act 1992;