Validated Target definition

Validated Target means a Target that has been validated in vitro ---------------- or in vivo as part of a TVD program by ATUGEN or its Collaborator.

Validated Target means a Target which has been shown to meet all of the following criteria approved by the PC: (a) the Target is well characterized (i.e., its biochemical and physiological actions are reasonably well understood); (b) agents, ligands, or intracellular molecules that interact with the Target demonstrate a desired effect on a biological process in relationship to a disease state or disorder; and (c) the Target is shown to be present in human tissue with the disease state or condition.

Validated Target means a biological drug target against which any drug has received Marketing Authorization Approval.

Examples of Validated Target in a sentence

• The PMT will confirm the Validated Target Price (VTP), the Validated Target Schedule (VTS) and the Validated Target Cost (VTC), in writing as the Project Objective and the Parties will incorporate the executed Project Objective document into this Agreement as Exhibit B.

• The Project Objective is comprised of the Validated Target Program (VTP), Validated Target Cost (VTC), and Validated Target Schedule (VTS), which establishes the Project requirements and metrics for measuring the Project’s success.

• The Collaboration Agreement will expire upon the expiration of the last to expire royalty payment obligation with respect to all Products in all countries, subject to earlier expiration if all option exercise periods for all Validated Target Pairs expire without AbbVie exercising any option.

• Protein Kinase Cε Is a Predictive Biomarker of Aggressive Breast Cancer and a Validated Target for RNA Interference Anticancer Therapy.

• The Extension Fee payable by Novartis to extend the Exclusivity Term with respect to any Novel Validated Angiogenesis Project Target shall be as specified (with respect to any Novel Validated Target) pursuant to Section 7.5 of the Collaboration Agreement.

More Definitions of Validated Target

Validated Target means any one or more of the following: (i) NMDA channels, (ii) sodium channels, and/or (iii) both NMDA and sodium channels, if so designated by the Research Management Committee pursuant to Section 4.1, or other glutamate-activated channels that the Research Management Committee determines from time to time.

Validated Target means the *** .

Validated Target means a biological molecule that (a) is a [**], a Protein [**] by a [**] or another qualifying biological molecule in a relevant [**] of which or the [**] is based upon the identification of a [**], and (b) that (i) has been configured into a research assay that is suitable for the [**] and which research assay is (1) a biochemical assay (including without limitation, a competitive binding assay for a receptor or an enzyme substrate conversion assay), or (2) a reporter based assay, in either case having a robust assay readout (such as fluorescence, chemiluminescence, and/or radioactivity) that has the potential to be configured into a high throughput screen and is therefore suitable for undertaking research activities to develop a high throughput screen, or (ii) is suitable for use in [**] or (iii) is suitable for use in [**] development efforts, all as determined in good faith by the Joint Management Team. Unless stated otherwise, a Validated Target shall include a Genetics Validated Target.

Validated Target has the meaning forth in Section 2.1.3.

Validated Target means either an In Vitro Validated Target and/or an In Vivo Validated Target.

Validated Target means any Gene Target discovered or identified in the course of the Project, which is designated by the JSC as validated in accordance with the Validation Criteria in effect at the time the applicable quarterly report detailing such Gene Target is submitted to the JSC.

Validated Target means a biological molecule (e.g., receptor, enzyme, ion channel or protein domain) or Gene, the function of which has been identified and which has been determined by the Management Committee to be potentially useful in the discovery of a Drug. As used in this Agreement, the following terms shall have the respective meanings specified in the Sections indicated below. Section ------- [*]