Specifically Binds definition

Specifically Binds means, in the case of a SMIP or other protein, the binding of such SMIP or other protein to a Target (or a portion thereof) above the level of background binding and wherein such SMIP or other protein is designed or being developed to exert its biological effect through binding to such Target (or such portion thereof).
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Specifically Binds means binding with a dissociation constant (Kd) of at least 10-6M.
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Specifically Binds refers to those antibodies that have a minimum affinity (KD value) of [******] (as measured by standard techniques such as the BIAcore) toward a specified antigen and do not bind to related isozymes, proteins or antigens with an affinity of better than 1 uM. Portions of this Exhibit were omitted and have been filed separately with the Secretary of the Commission pursuant to the Company’s application requesting confidential Investment under Rule 24b-2 under the Securities Exchange Act of 1934.
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Examples of Specifically Binds in a sentence

  • LmPC Specifically Binds and Is Inhibited by c-di-AMP.‌(A) Binding titration of c-di-AMP and LmPC using32P-c-di-AMP.(B) Enzymatic activity of LmPC in the presence of Acetyl-CoA (100 mM), varied pyruvate, and c-di- AMP concentrations as indicated.(C) Rate constants of pyruvate turnover in the presence of c-di-AMP.(D) Enzymatic activity of LmPC in the presence of pyruvate (20 mM), varied Acetyl-CoA (allosteric activator) and c-di-AMP concentrations as indi- cated.

  • RESULTS KRP2 Specifically Binds and Inhibits CDKA;1 and Not CDKB1;1Previously, the interaction of KRP proteins with the archetypical A-type CDKA;1 but not with the B-type CDKB1;1 has been dem- onstrated by yeast two-hybrid analysis (Lui et al., 2000; De Veylder et al., 2001; Zhou et al., 2002).

  • Alba, A.E.M.d., et al., VIRUS-CELL INTERACTIONS-A Bromodomain-Containing Protein from Tomato Specifically Binds Potato Spindle Tuber Viroid RNA In Vitro and In Vivo.

  • Heh2 Specifically Binds Snf7To evaluate the interactions between Heh1/2 and Snf7 biochem- ically, we affinity purified Heh1/2-GFP from whole cell extracts of wild-type (WT) cells using conditions that maintain interactions between the Heh proteins and Pom152 and Nup170 (Yewdell et al., 2011); we could not detect Snf7 bound to either Heh1- or Heh2-GFP (Figure 3A).

  • Ectopic Expression of HY5 Reduces the Abundance of BZR1 and HY5 Specifically Binds to the Dephosphorylated Form of BZR1Based on the findings that light affects the phosphorylation status and abundance of BZR1 and that HY5 interacts with BZR1 in vivo, we next examined whether an alteration in HY5 protein abun- dance affects BZR1 accumulation in plants.

  • RESULTS The SHARPIN UBL Domain Specifically Binds to the UBA Domain of HOIP ~ ~ To clarify the interaction mechanism between HOIP and SHARPIN, we first used the GFP-tagged SHARPIN UBL domain (residues 206–309) (hereafter referred to as SHARPINUBL) to map its binding region in HOIP by co-immunoprecipitation (coIP) assay.

  • The school shall provide an instructional program in chemical abuse and the prevention of chemical dependency.

  • ELAV Directly and Specifically Binds to Neuronal APA TargetsNext, we assessed whether ELAV exerts its function through direct binding to the functional targets identified above.

  • References herein to any ADC “directed to” or “with respect to” a particular Target mean that such ADC comprises an Antibody that Specifically Binds such Target.

  • HgII Ion Specifically Binds with T:T Mismatched Base Pair in Duplex DNA.


More Definitions of Specifically Binds

Specifically Binds means binding with a dissociation constant (Kd) of at least [**].
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Specifically Binds means [***].
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Related to Specifically Binds

  • Technically Feasible refers solely to technical or operational concerns, rather than economic, space, or site considerations.

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  • Contractor Commercially Sensitive Information means the information listed in the Contractor Commercial Sensitive Information Annex to the Contract being information notified by the Contractor to the Authority which is acknowledged by the Authority as being commercially sensitive information.

  • Collaboration Know-How means all Know-How conceived, discovered, developed or otherwise made by or on behalf of a particular Party or any of its Affiliates or permitted subcontractors of any of the foregoing (solely or jointly by or on behalf of a particular Party or any of its Affiliates or permitted subcontractors of any of the foregoing) in the course of [***].

  • Joint Know-How has the meaning set forth in Section 8.1.2.

  • Additional SDU Study means a deliverability study that a Developer may elect to pursue as that term is defined in OATT Section 25 (OATT Attachment S). For purposes of Section 23.4.5 of this Attachment H, “Affiliated Entity” shall mean, with respect to a person or Entity:

  • Commercially Sensitive Information means the Information (i) listed in the Commercially Sensitive Information Schedule; or (ii) notified to the Authority in writing (prior to the commencement of this Contract) which has been clearly marked as Commercially Sensitive Information comprised of information:

  • Sexually Explicit Material means any depiction of actual or simulated sexually explicit conduct.

  • Therapeutically equivalent drug products means drug products that contain the same active ingredients and are identical in strength or concentration, dosage form, and route of administration and that are classified as being therapeutically equivalent by the U.S. Food and Drug Administration pursuant to the definition of "therapeutically equivalent drug products" set forth in the most recent edition of the Approved Drug Products with Therapeutic Equivalence Evaluations, otherwise known as the "Orange Book."

  • License Type means the identification of whether the license for a Software Product is for a Perpetual Term or Subscription Term as specified in the Quote.

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  • Massive Multiauthor Collaboration Site (or “MMC Site”) means any World Wide Web server that publishes copyrightable works and also provides prominent facilities for anybody to edit those works. A public wiki that anybody can edit is an example of such a server. A “Massive Multiauthor Collaboration” (or “MMC”) contained in the site means any set of copyrightable works thus published on the MMC site.

  • Program Materials means the documents and information provided by the Program Administrator specifying the qualifying EEMs, technology requirements, costs and other Program requirements, which include, without limitation, program guidelines and requirements, application forms and approval letters.

  • Product Know-How means Know-How

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  • Research Use shall have the meaning given in Section 2.2.2 of this Agreement.

  • Commercially Sensitive Information Schedule means the Schedule containing a list of the Commercially Sensitive Information.

  • Project specific information means such part of the Instructions to Consultants used to reflect specific project and assignment conditions.

  • Specifically Authorized Representative (SAR), as used in this clause, means any person the Contracting Officer has so designated by written notice (a copy of which shall be provided to the Contractor) which shall refer to this subparagraph and shall be issued to the designated representative before the SAR exercises such authority.

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  • Specially Written Software means any software created by the Contractor (or by a third party on behalf of the Contractor) specifically for the purposes of this Contract.

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  • Additional Indication means any indication other than the Initial Indication.

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