Specific Aim definition

Specific Aim. 2: Dose ranging of S-MRI-1867 for skin exposure Approaches for Aim 2:
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Specific Aim. 1: To evaluate the relationship between HIV-positive pregnant women in Zambia and the role and influence that their Christian faith has on HAART adherence. We will hold key informant interviews and surveys with 508 HIV- positive pregnant women as well as 100 identified Christian leaders who actively engage in counseling HIV-positive pregnant women through ministry within Lusaka. These interviews will assess the viewpoints, perceptions and opinions about HAART and how adherence is affected by religion. Specific Aim 2: To improve HAART adherence among HIV-positive pregnant women. We will create and implement trainings that are culturally appropriate to 100 Christian leaders within Lusaka, Zambia. These trainings will strengthen counseling skills among local religious leaders who routinely counsel HIV-positive women in the course of their work. Christian leaders who work at a community level and understand the benefits of HAART will then be able to encourage adherence within a religious framework. This will affect the long term adherence of HAART by HIV-positive pregnant women. Research Strategy
Sample 1
Specific Aim. 2: Explore the relationship between self-care and health outcomes (functional capacity, symptom burden, and HRU) in ACHD. H2: Controlling for heart defect severity and number of comorbidities, lower levels of self-care will be associated with:
Sample 1

Examples of Specific Aim in a sentence

  • If an applicant has multiple Specific Aims, then the applicant may address Significance, Innovation and Approach for each Specific Aim individually, or may address Significance, Innovation and Approach for all of the Specific Aims collectively.

  • The Annual Report should include:• A description of the completion status of each Specific Aim and/or research objective or milestone for the budget period.• A complete list of the publications planned or completed to date - including status (e.g., published [include reference], in review, under development).• A description of any changes made in the use of human subjects or IRB approval status.• A description of any changes made in the Data Management Plan.

  • The topic can be related to work that is currently being conducted in the student’s home lab, but must involve a novel component, for example one Specific Aim which is different from other aims that the lab has researched or proposed research on; some preliminary data collection, or analysis of existing data, by the student.

  • The applicant may address Significance, Innovation and Approach for each Specific Aim individually, or may address Significance, Innovation and Approach for all of the Specific Aims collectively.

  • Each primary Specific Aim may be broken down into as many or few secondary sub-Specific Aims as the candidate feels appropriate or necessary for the experiments being proposed.

  • If the qualifying exam proposal has multiple Specific Aims, then the applicant may address Significance, Innovation and Approach for each Specific Aim individually, or may address Significance, Innovation and Approach for all of the Specific Aims collectively.

  • A full discussion on the use of select agents should appear in the Select Agent Research attachment, below.If an applicant has multiple Specific Aims, then the applicant may address Significance, Innovation and Approach for each Specific Aim individually, or may address Significance, Innovation and Approach for all of the Specific Aims collectively.

  • Specific Aim 1: To compare HIV+ and HIV- women undergoing the menopausal transition with respect to bone turnover markers and rates of trabecular and cortical bone loss.Specific Aim 2: To determine the effects of estrogen deficiency on T cell activation, osteoclast and osteoblast precursors and osteoblast apoptosis in HIV+ and HIV- women.Specific Aim 3: To compare HIV+ and HIV- women undergoing the menopausal transition with respect to changes in muscle mass, strength, and functional measures of fall risk.

  • This report should consist of 2- 5 pages describing (1) the progress made in each Specific Aim since the previous meeting (helpful figures/tables are encouraged), (2) planned experiments for each Aim, and (3) any additional information such as presentations at scientific meetings or publications underway.

  • For Specific Aim 2, the same power calculations for Aim 1 apply; however, tests of indirect effects are exploratory, we will be powered to detect a moderate indirect effect (a*b = 0.25), using the same constraints as above.


More Definitions of Specific Aim

Specific Aim. 2: Identify overall patient characteristics of CAM users and non- users. There is a paucity of research studies that examine patient perceptions to both CAM and CAM users. It is important to determine who is using CAM before trying to develop theories to explain the growing popularity of CAM use among cancer patients. CAM users and non-users may have significant and important differences that may impact CAM use in the population identified as particularly likely to benefit from CAM. Finding these potential differences will assist in understanding if patient’s perceptions regarding CAM use might limit the uptake of potentially useful CAM therapies. In addition, the research may identify socio-economic, gender, and ethnic groups, also known as “under-represented minorities” (URM) suffering from end-stage cancer that may or may not be using CAM. This information could be valuable in order for the field to be cognizant of who may be using CAM and can provide opportunities for patient education. Specific Aim 3: Assess communication of CAM usage between the patient and the patient’s oncologist, primary care physician or palliative care team. CAM is often used alongside conventional medical care, yet many patients don’t disclose CAM use to their physicians. Serious adverse events are possible due to CAM usage, so it is vital that patient’s teams are aware of exactly what they are using and how often. It is also important to understand the reasons patients do not often disclose CAM usage. The findings of the proposed study will be useful to gain that knowledge, and may assist in creating awareness to these issues. There are future opportunities to incorporate usage of CAM into patient medical questionnaires or other ways of discovering if patients are using any CAM therapies or products. Insufficient disclosure of CAM to conventional providers represents a serious challenge in medical encounter communications. Research Strategy
Sample 1
Specific Aim. 4: Informed by guidance from the Community Coalition, ABCH and LRU will prepare and implement sustainability plans. Specific Aim 5: Informed by guidance from the Community Coalition, ABCH and LRU will prepare and implement dissemination plans that focus on community and academic dissemination priorities. Dates for this Memorandum of Understanding: The grant project period is from 08/01/20XX-07/31/20XX. This memorandum is intended to cover the entire grant period. Responsibilities of Local Research University:
Sample 1
Specific Aim. 2: Use linear and logistic regression to model the relationship between connectivity to home behaviors again the outcomes: a) depression and b) severity of depression. This research is important because it can potentially shape the way that we understand how immigrants experience cross-border connections and what the implications are for their mental health. The findings from this project can also provide a guide for health care providers in helping immigrants to overcome depression, and what specific connectivity behaviors to look for in a patient. Although each immigrant and the region that they come from have unique cultural manifestations of mental health issues, it is critical to understand the broad behaviors that are indicative of possible depression across all immigrant groups. REVIEW OF THE LITERATURE
Sample 1
Specific Aim. 1: In vitro testing of anti-S1P Mab’s ability to reduce S1P-dependent cell proliferation and metastatic potential.
Sample 1
Specific Aim. 1: Test the target-specificity of hybrid peripheral CB1R/iNOS inhibitors by analyzing their anti-fibrotic efficacy in mice with genetic deletion of CB1R or iNOS, using the subcutaneous bleomycin-induced skin fibrosis model. This approach would help Licensee to evaluate the relative contribution of the two targets to the therapeutic efficacy of the hybrid inhibitor. Approaches for Aim 1:
Sample 1
Specific Aim. 1: Design, fabricate, and characterize ultrasound probes for transrectal BH studies. We will simulate nonlinear HIFU fields generated by transrectal probes with different geometries to design a transducer capable of operating in shock-forming conditions relevant to BH. Parameters of FDA-approved HIFU devices (e.g. Ablatherm and Sonacare) will be used as a starting point to meet clinical constraints for prostate treatments and power limitations of the system. Based on design calculations, a transrectal prototype probe integrated with a miniature ultrasound imaging probe will be constructed for ex vivo and preclinical studies in canines. The integrated device will include the imaging system (B&K 3000 commonly used in urology practice), the transrectal HIFU transducer (fabricated by a vendor per our specifications) and the computer-controlled driving electronics (E&I power amplifier and function generator). Acoustic characterization of the HIFU probe will be performed in water, including hydrophone measurements in linear and nonlinear regimes and acoustic holography. The holography measurements will be used to set a realistic boundary condition for rigorous numerical modeling to predict nonlinear acoustic fields and temperature fields in prostate tissue (Xxxxxxx 2015).
Sample 1

Related to Specific Aim

  • Customer Specific Training means a private Course organized on demand specifically for Customer.

  • Specific Terms in relation to a Loan means the specific terms applicable to that Loan as set out in the document entitled ‘Specific Terms’ related to that Loan;

  • Specific Plan means the Sunset Specific Plan.

  • Product Specific Terms means the terms applicable to a specific item of Licensed Software as set out in Schedule 2;

  • Service Specific Terms has the meaning given in the G Suite Agreement or Complementary Product Agreement, as applicable, or, if Customer’s G Suite Agreement does not define “Service Specific Terms”, means the then-current terms specific to one or more Core Services for G Suite set out at xxxxx://xxxxxx.xxxxxx.xxx/terms/service-terms/.

  • product type means any of the following:

  • MSAA Indicator Technical Specifications document means, as the context requires, either or both of the document entitled “Multi-Sector Service Accountability Agreement (MSAA) 2019-20 Indicator Technical Specifications November 5, 2018 Version 1.3” and the document entitled “Multi-Sector Service Accountability Agreement (MSAA) 2019-20 Target and Corridor-Setting Guidelines” as they may be amended or replaced from time to time;

  • technical specification means, with respect to any Software, the document setting forth the technical specifications for such Software and included in the Statement of Work.

  • Specific local tax means a tax levied under 1974 PA 198, MCL 207.551 to 207.572, the commercial redevelopment act, 1978 PA 255, MCL 207.651 to 207.668, the technology park development act, 1984 PA 385, MCL 207.701 to 207.718, and 1953 PA 189, MCL 211.181 to 211.182. The initial assessed value or current assessed value of property subject to a specific local tax shall be the quotient of the specific local tax paid divided by the ad valorem millage rate. However, after 1993, the state tax commission shall prescribe the method for calculating the initial assessed value and current assessed value of property for which a specific local tax was paid in lieu of a property tax.

  • Brand Name Specification means a specification limited to one or more items by manufacturers’ names or catalogue number.

  • Non-Microsoft Product means any third-party-branded software, data, service, website or product, unless incorporated by Microsoft in a Product.

  • Technical Specifications means the detailed requirements for the Work furnished by the Architect and set forth in Book 3 of the Contract Documents.

  • Product Schedule means PTC’s standard order form entitled “PTC Product Schedule” (including all schedules, attachments and other document(s) specifically referenced therein) or such alternative order form as may be submitted by Customer and accepted by PTC, in each case that specifies (i) the Licensed Products and/or Services ordered; and (ii) for Licensed Products, the installation address (including the Designated Country) and the Licence Term.

  • Reference biological product means the single biological product licensed pursuant to 42 U.S.C.

  • Civil Aeronautical Product means any civil aircraft, aircraft engine, or propeller or subassembly, appliance, material, part, or component to be installed thereon.

  • Contract Specifications means the principal trading terms in CFD (for example Spread, Swaps, Lot Size, Initial Margin, Necessary Margin, Hedged Margin, the minimum level for placing Stop Loss, Take Profit and Limit Orders, financing charges, charges etc) for each type of CFD as determined by the Company from time to time.

  • License Type means the identification of whether the license for a Software Product is for a Perpetual Term or Subscription Term as specified in the Quote.

  • Technical Support Services means the technical support and maintenance Services provided by us according to our then-current technical support policy and procedure listed at xxxxxxxxxxxxx.xxx (“Technical Support Policy”) when the Services are purchased.

  • Alternative nicotine product means any vaping product, whether or not it includes nicotine, including electronic smoking devices, that can be ingested into the body by chewing, smoking, absorbing, dissolving, inhaling, or by any other means. ‘Alternative nicotine product’ does not include:

  • Contract Manufacturer means a company that produces goods under contract for another company under the label or brand name of that company.

  • SAP Training Catalogue means the catalogue published by SAP containing details of SAP training courses and services.

  • Runtime Product means the version specific files and application program interfaces (APIs) specified in the RUNTIME.TXT file provided with SAP Crystal Reports 2008, SAP Crystal Reports for Eclipse 2.0, and SAP Crystal Reports for Visual Studio 2010.

  • Project Specific IPRs means: (a) IPRs in the Services provided by the Supplier (or by a third party on behalf of the Supplier) specifically for the purposes of the Contract and all updates and amendments of these items created during the Contract Period; and/or (b) IPRs arising as a result of the provision of the Services by the Supplier (or by a third party on behalf of the Supplier) under the Contract, [including the rights in or to any database developed and supplied by the Supplier to the Customer in accordance with the terms of this Contract;

  • Statement of Work means the description of activities performed in completing the Project, as specified in the Contract and as may be amended.

  • Manufacturing Facility means buildings and structures, including machinery and equipment, the primary purpose of which is or will be the manufacture of tangible goods or materials or the processing of such goods or materials by physical or chemical change.

  • Manufacturing Cost means [***].