Objective 1. [Insert first project objective] [Make duplicate copies of this Section 2.1.1 as needed] The following table sets forth the supported tasks, their durations and costs. [Below is an example table to be filled in to break the project down into subpart tasks, duration and cost] Task Number Task Description Duration Cost Task 1.1 Task 1.2 Task 1.3 Task 1.4 Task 1.5 Task 1.6
Objective 1. Conduct general grant administration and deliver a project research or outreach plan, required meetings, quarterly and annual progress reports, invoices, and a final report.
Objective 1. Assess cell viability of synthetic uttroside B, compared to plant Uttroside B, sorafenib and regorafenib Background Cell Viability Study: Synthetic Uttroside B will be assessed in various hepatocellular carcinoma (HCC) cell lines to assess cell viabilities associated with synthetic Uttroside B treatment, and compared to sorafenib and regorafenib. The goal is to assess the efficacy of synthetic uttroside B, compared to plant extract Uttroside B, as well as sorafenib (the current drug for HCC), and Regorafenib – stivarga, which is currently in clinical trial and seems to be promising compared to sorafenib. HCC pre-clinical orthotopic and transgenic models: The orthotopic Huh7 HCC xenograft model will be used in Objective 2 to assess the efficacy of synthetic uttroside B, and compared to both sorafenib and Regorafenib. Objective 2: Assess the efficacy of synthetic uttroside B in pre-clinical orthotopic mouse models for HCC (HuH7 orthotopic xenograft model in nude mice), using MR imaging techniques. Background MRI diagnosis of HCC: MRI is considered to be superior to computed tomography (CT) in detecting HCC tumors due to its improved contrast resolution and tissue characterization. In addition, the MRI method diffusion- weighted imaging (DWI), which assesses tissue structural alterations associated with disease pathology, can be used to detect early treatment response that correlates well with necrosis, by measuring ADC (apparent diffusion coefficient) values. Both contrast-enhanced MRI and DWI will be used in Objective 2 to assess the efficacy of synthetic uttroside B. HCC pre-clinical orthotopic model: We will use an orthotopic xenograft model (HuH7 cell-derived tumor tissue in Balb/c nude mice) for the in vivo studies. Synthetic uttroside B will be compared to Regorafenib and sorafenib, as well as untreated tumor-bearing animals. Following intrahepatic cell implantations, mice will be imaged by contrast-enhanced MRI (CE-MRI) (7 Tesla 30-cm horizontal-bore magnet) to assess tumor growth. Once tumors reach 10-20 mm3 in volumes, mice will be separated into 4 groups (untreated (5 mice), or treated with either synthetic uttroside B (10 mg/kg 3x/week i.v.; 10 mice), sorafenib (5 mice) or Regorafenib (10 mice)). Over the course of 6-8 weeks, mice will be imaged by CE-MRI to calculate tumor volumes, and by DWI to assess ADC values that will be a quantitative measure of tissue structural alterations from tumor growth and treatment response. Tumor tissue samples fro...
Examples of Objective 1 in a sentence
The candidate will understand and recommend a manual rate for each of the coverages described in Learning Objective 1.
Note: Provisioning timelines include extended demarcation wiring when appropriate.Measurement Process: Objective 1: Individual Service Installations: Install intervals are based on the committed installation intervals established in this SLA or due dates negotiated between the Customer and the Contractor.
For each objective and activity (i.e. Objective 1, Activity 1.1, Activity 1.2, etc.), explain the progress achieved and relevant constraints (e.g. evaluations, HSCC meetings).
Similarly, hybridization of one 2s orbital and two 2p orbitals form three sp2 hybridized orbitals and one unhybridized p orbital which results in trigonal planer geometry (Figure 1.1 b).
Objective #1: Decrease the percentage of adults in “poor” mental health.
More Definitions of Objective 1
Objective 1. At least ninety percent (90%) of clients shall rate services as satisfactory. XXXXXXX D. SALARIOSA DBA PORTOBELLO CARE HOME FY 2010– 2013 EXHIBIT B In consideration of the services provided by Contractor in Exhibit A, County shall pay Contractor based on the following fee schedule:
Objective 1. At least ninety percent (90%) of clients shall rate services as satisfactory. 000 XXXXXXX XXXXXX, LLC/INDUSTRIAL HOTEL FY 2009 – 2012 Exhibit B In consideration of the services provided by Contractor in Exhibit A, County shall pay Contractor based on the following fee schedule:
Objective 1. Improve student literacy skills (K-12) with a focus on reading achievement 30% 25% 20% 15% 10% At Risk At Risk At Risk Kindergart en Grade 1 Grade 2 Performance Indicators • District Early Success Assessments K-2 • Primary Reading Assessments based on BC Performance Xxxx- dards District Early Success Assessment (% at risk in one or more areas of oral language, phonemic awareness, concepts of print) Performance Target
Objective 1. Individual Service Request: Service installed on or before the committed interval or negotiated due date. 2. Objective 2: Successful Install Monthly Percentage per Service: Rights and Remedies Per Occurrence: Objective 1: Individual Service Request: 50 percent of installation fee credited to Customer for any missed committed objective. Monthly Aggregated Measurements: Objective 2: 100 percent of the installation fee credited to Customer for all Service Requests (per same service type) that did not complete on time during the month if the Successful Install Monthly Percentage is below the committed objective. Basic (B) (Calendar Days) Standard (S) (Calendar Days) Premier (P) (Calendar Days) Bidders Objective Commitment (B, S or P) Long Distance Domestic Calling N/A ≥ 90% ≥ 95% P LD DS1 Access Transport N/A ≥ 90% ≥ 95% P LD PRI on DS1 Access Transport N/A ≥ 90% ≥ 95% P LD DS3 Access Transport N/A ≥ 90% ≥ 95% P 1.4.4.8.8 Provisioning - Calling Card (M-S) SLA Name: Provisioning – Calling Cards Definition: Calling Card provisioning is defined as issuing new Calling Cards on or before the interval dates provided in this SLA or due date negotiated between the Customer and Contractor. Measurement Process: The duration of time beginning when a completed Service Request is placed for a calling card(s) until Contractor activation and delivery of the ordered card(s), following Customer account setup. Service(s): Interval Calling Cards- Service Requests under 500 (Section 1.4.2.4) 10 Business Days Calling Cards - Service Requests over 500 (Section 1.4.2.4) 45 Business Days Objective (s): Activated cards delivered to the Customer within the intervals provided in this SLA or by the due date negotiated between the Customer and Contractor. This objective is the same for Basic, Standard and Premium Commitments. Rights and Remedies Per Occurrence: $1.00 rebate to the Customer per card per day that each card is not activated and delivered to the Customer within the interval listed in this SLA. Monthly Aggregated Measurements: N/A Basic (B) Standard (S) Premier (P) Bidders Objective Commitment (B or S) Long Distance Domestic Calling 10 hours 6 hours N/A S Audio Conferencing 10 hours 6 hours N/A S
Objective 1. The level of representation of women and youth in community organizations supported by the project is increasing. Indicator 1: 30% of the members of the consultation structures are women and young people. Strengthen the capacity of women in the field promoting their leadership (public communication, negotiation, leadership, group management) Objective 2: The specific needs of women, girls and persons with disabilities in WASH are discussed openly Indicator 2: The sector monitoring and evaluation system includes at least three indicators to assess the promotion of gender equality Support the Monitoring and Evaluation Directorate of the Ministry in charge of WASH on the adjustment of the monitoring and evaluation system
Objective 1. Improve student literacy skills (K-12) with a focus on reading achievement 30% 25% 20% 15% 10% At Risk At Risk At Risk Kindergart en Grade 1 Grade 2 Performance Indicators • District Early Success Assessments K-2 • Primary Reading Assessments based on BC Performance Xxxx- dards Performance Target District Early Success Assessment (% at risk in one or more areas of oral language, phonemic awareness, concepts of print) Summary of Progress • District Early Success Assessments indicate fewer number of grade 1 students and fewer grade 1 & 2 Aboriginal students at risk • Primary Reading As- sessments indicate students fully meeting or exceeding has in- creased over three years. • Data indicates female students are close to meeting target while male students and Aboriginal learners are not (more details in appendix) • Decrease percentage of students at risk to 15% or less within three years. Jun- 07 Jun- 08 Jun- 09 District Primary Reading Assessment (based on BC Performance Standards % fully meeting, & exceeding) 80% 70% 60% 50% 40% 30% 20% 10% All St udent s Aboriginal All St udent s Aboriginal All St udent s Aboriginal Grade 1Reading Grade 2 Reading Grade 3 Reading 2006 2007 2008 2009 Performance Target • 75% or more of all grade 1-3 students will fully meet or exceed expectations in reading within three years. • 50% or more of all grade 1-3 Aboriginal students will fully meet or exceed expectations in reading within three years.