NK Cells definition

NK Cells means natural killer cells.
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NK Cells means natural killer cells. 1.58 “NK Cells and Gamma Delta T Cell Products” means any pharmaceutical or biological product, process or therapy developed under or arising from the NK Cells and Gamma Delta T Cell Program, including all forms, formulations, presentations, doses, administrations and package configurations. 1.59 “NK Cells and Gamma Delta T Cell Program” means a program(s) of Research and Development focused on NK Cells and Gamma Delta T Cells. 1.60 “Non-Exclusive Products” means (a) NK Cells and Gamma Delta T Cell Products, and (b) TCR Non-Exclusive Products, in each case as generated or Developed by Alaunos. For clarity, Non-Exclusive Products include all forms, formulations, presentations, doses, administrations and package configurations thereof. 1.61 “Oncology” means the treatment or prevention of a human patient who has received a cancer diagnosis. 1.62 “Patents” means (a) pending patent applications, issued patents, utility models and designs; (b) reissues, substitutions, confirmations, registrations, validations, re-examinations, continuations, continued prosecution applications, continuations-in-part, or divisions of or to any of the foregoing; and (c) extensions, renewals or restorations of any of the foregoing by existing or future extension, renewal or restoration mechanisms, including supplementary protection certificates or the equivalent thereof. 1.63 “Precigen” means the Virginia corporation, with its principal place of business at 00000 Xxxxxx Xxxxxxx Xxxxxxx, Germantown, MD 20876 along with its wholly owned subsidiaries and Affiliates.
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NK Cells means an innate lymphocyte that: (a) displays rapid effector responses on encounter with an infected, allogeneic, or transformed cell; (b) does not express a TCR; and (c) recognizes target cells through a balance of signals from activating receptors, which recognize stress-induced ligands, and inhibitory receptors, which predominantly engage MHC class I molecules. [*****].
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Examples of NK Cells in a sentence

  • Mutations in the core of IL-2 improve affinity to CD122 on CD8 T cells and NK Cells, as CD122 affinity is key for the activation of immune cells responsible for cancer killing (CD8+ T cells, naive T cells, NK cells).Additionally, MDNA109 reverses NK cell anergy and acts with exceptional synergy when combined with checkpoint inhibitors.

  • As of the Effective Date, GCLC is a party to agreements with the following Third Parties that relate to NK Cells, Licensed Products or Information or Patents related to NK Cells or Licensed Products: [***] (the “Existing Third Party Agreements”).

  • U.S. Provisional Application No. 61/224,771 filed on July 10, 2009 and U.S. Provisional Application No. 61/301,529 filed on February 4, 2010 both entitled “Preserved Compositions of Activated NK Cells and Methods of Using the Same” and any derivatives thereof.

  • Xxxxxxx, Xx., Ph.D. Title: President and Chief Executive Officer UCL Business PLC By: /s/ Xxxx Xxxx Name: Xx. Xxxx Xxxx Title: Executive Director SCHEDULE 1 Patents Patent Application UK 0514288.0 filing date 17/3/05 and the refiled patent application UK 0505508.2 filing date 12/7/05 both entitled “Ex Vivo Generation of Tumour Restricted Natural Killer (NK) Cells for Therapeutic Use” and any derivatives thereof.

  • Binds Strongly to Non-Target Cells, Causing Toxicity and Limiting Efficacy α β β IL-2 Off-Target Cells Effector Cells IL-2IL-2 Building a Neoleukin Cytokine Mimetic in 4 Steps 1 2 3 4 Crystal Structure Shows Neo-2/15 Binding Beta/Gamma as Predicted ALPHA BETA GAMMA IL-2 Neo-2/15 BETA GAMMA 14% Nature NL-201 Stimulates CD8 Effector T and NK Cells More Selectively Than IL-2 0.


More Definitions of NK Cells

NK Cells means: human iPSC (including TiPSC) derived NK cells.
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Related to NK Cells

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  • Manufacturing Technology means any and all patents, patent applications, Know-How, and all intellectual property rights associated therewith, and including all tangible embodiments thereof, that are necessary or useful for the manufacture of adeno- associated viruses, adeno-associated virus vectors, research or commercial reagents related thereto, Licensed Products, or other products, including manufacturing processes, technical information relating to the methods of manufacture, protocols, standard operating procedures, batch records, assays, formulations, quality control data, specifications, scale up, any and all improvements, modifications, and changes thereto, and any and all activities associated with such manufacture. Any and all chemistry, manufacturing, and controls (CMC), drug master files (DMFs), or similar materials provided to regulatory authorities and the information contained therein are deemed Manufacturing Technology.

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