Limit of quantification definition

Limit of quantification or “LOQ” means the minimum levels, concentrations, or quantities of a target variable, for example, an analyte that can be reported by a laboratory with a specified degree of confidence.
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Limit of quantification means a concentration of an analyte at which one can state with a degree of confidence, using the most sensitive analytical test method approved by EPA, for that sample matrix that an analyte is present at a specific concentration in the sample tested.
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Limit of quantification means a stated multiple of the limit of detection at a concentration of the determinand that can reasonably be determined with an acceptable level of accuracy and precision. The limit of quantification can be calculated using an appropriate standard or sample, and may be obtained from the lowest calibration point on the calibration curve, excluding the blank;
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Examples of Limit of quantification in a sentence

  • Limit of quantification (LOQ) was estimated based on a 10:1 signal-to-noise ratio.

  • The purchased equipment should be able to meet the requirements of the LOD and LOQ (Limit of detection and Limit of quantification) for the relevant parameters as specified in FSSR, FSSAI Manuals, Relevant test methods and be compliant to the requirements of ISO 17025.

  • Limit of detection and Limit of quantification The limit of detection (LOD) and the limit of quantification (LOQ) of the drug were derived by calculating the signal-to- noise ratio (S/N, i.e., 3.3 for LOD and 10 for LOQ) using the following equations designated by International Conference on Harmonization (ICH) guidelines19.LOD = 3.3 × σ/S LOQ = 10 × σ/SWhere, σ = the standard deviation of the response and S = slope of the calibration curve.

  • Table 3.8 Limit of quantification values assessed ConcentrationMean peak areaStandard deviation% RSD(μg/ml)(n = 3) 0.50752584.678.500.330.40602048.676.350.310.30451537.3311.680.760.20301007.334.160.410.1015502.3329.875.95 The LOQ was found to be 0.2 μg/ml which had a percent RSD value of 0.41% and therefore by convention the LOD value is taken to be 0.06 μg/ml.

  • USP describes eight steps for endorsement.Accuracy, Precision, Specificity, Limit of Detection, Limit of quantification, Linearity and range, Ruggedness, Robustness The Analytical method validations criteria were defined based on the purpose of their use.

  • Among the social and political distinctions of the successive phases, it is also important to take into account the ideological arsenal of the bourgeois class, which it has made use of since the beginning of its revolutionary struggle and whose employment reflects the successive changes that derive from the fact that the bourgeoisie became an autonomous, ruling and ultimately a counterrevolutionary class.

  • LOQ = Limit of quantification, which for the ZmPSY1 ELISA in straw (stem) samples was 66.4 ng/g FWT and for CRTI in straw samples was 6.2 ng/g fw.

  • Limit of quantification for Ti in food was 0.01 mg Ti/g product (Peters et al.

  • Limit of quantification of the method sufficiently low for HBM4EU samples (indicate how the LOQ was determined)4.

  • Limit of quantification is calculated from signal to noise ratio.


More Definitions of Limit of quantification

Limit of quantification. (LOQ): means the lowest level achieved and reported by routine monitoring with validated methods in accredited laboratories as defined in Regulation (EC) No XXX/2003;
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Limit of quantification means a stated multiple of the limit of detection at a concentration of the determinand that can reasonably be determined with an acceptable level of accuracy and precision;
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Limit of quantification or “LOQ” means the minimum levels, concentrations, or quantities of a target
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Limit of quantification. LOQ’)’ means the lowest content of the analyte which can be measured with reasonable statistical certainty, i.e. the lowest concentration or mass of the analyte that has been validated with acceptable accuracy by applying the complete analytical method and identification criteria;
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Related to Limit of quantification

  • Limit of Quantitation or “LOQ” means a measurement of the concentration of a contaminant obtained by using a specified laboratory procedure calibrated at a specified concentration above the method detection level. It is considered the lowest concentration at which a particular contaminant can be quantitatively measured using a specified laboratory procedure for monitoring of the contaminant. This term is also sometimes called limit of quantification or quantification level.

  • SCHEDULE OF QUANTITIES, BILL OF QUANTITIES means the Schedule or Quantities as specified and forming part of contract.

  • Bill of Quantities means the priced and completed Bill of Quantities forming part of the tender.

  • The Schedule of Quantities/BOQ means the schedule of quantities as specified and forming part of this contract. Words importing persons include firms and corporations. Words importing the singular only, also include the plural and vice verse where the Context requires. 1.0 SCOPE OF WORKThe detailed scope of the work is given in the BOQ

  • Maximum Daily Quantity means the daily volume of Gas or Liquids, expressed in 103m3, identified in a Shipper's Interruptible Transportation Service Agreement that Transporter agrees to receive from Shipper under Toll Schedule Interruptible Full Path Service, Toll Schedule Interruptible Receipt Service or Toll Schedule Interruptible Delivery Service, as applicable.

  • Cost of Sales means any costs incurred of the type included in the “Cost of sales (excluding depreciation expense)” line item in the consolidated statement of operations of the Partnership prepared in accordance with GAAP, as presently applied.

  • Schedule of quantities means the schedule of quantities as specified and forming part of this contract.

  • The Schedule of Quantities means the schedule of quantities as specified and forming part of this contract.

  • Actual weight means the actual unladen weight of a vehicle or combination of

  • The schedule of quantity means the schedule of quantity as specified and forming part of this contract.

  • The Schedule of Quantities/ BOQ means the schedule of quantities as specified and forming part of this contract. Words importing persons include firms and corporations. Words importing the singular only, also include the plural and vice verse where the Context requires.

  • Bills of Quantities means the priced and completed Bill of Quantities forming part of the tender[where applicable].

  • Design requirements means the written description of the infrastructure facility to be procured pursuant to this article, including:

  • Type B quantity means a quantity of radioactive material greater than a Type A quantity.

  • Contract Quantity means the quantity of Gas to be delivered and taken as agreed to by the parties in a transaction.

  • Process weight means the total weight of all materials introduced into any source operation. Solid fuels charged will be considered as part of the process weight, but liquid and gaseous fuels and combustion air will not.

  • Sewage sludge weight means the weight of sewage sludge, in dry U.S. tons, including admixtures such as liming materials or bulking agents. Monitoring frequencies for sewage sludge parameters are based on the reported sludge weight generated in a calendar year (use the most recent calendar year data when the NPDES permit is up for renewal).

  • Maximum Weekly Starts means the maximum number of times that a generating unit can be started in one week, defined as the 168 hour period starting Monday 0001 hour, under normal operating conditions. Member:

  • Output means the exposure rate, dose rate, or a quantity related in a known manner to these rates from a brachytherapy source or a teletherapy, remote afterloader, or gamma stereotactic radiosurgery unit for a specified set of exposure conditions.

  • Peak tube potential means the maximum value of the potential difference across the x-ray tube during an exposure.

  • Priced Schedule of Quantities means the schedule of quantities duly priced with the accepted quoted rates of the contractor.

  • Normal Minimum Generation means the lowest output level of a generating resource under normal operating conditions.

  • Statement of Qualifications means a written statement submitted to a procurement unit in response to a request for statement of qualifications.

  • Contract Minimum Investment Requirement means, with respect to the Project, investment by the Company and any Sponsor Affiliates of at least $4,000,000 in Economic Development Property subject (non-exempt) to ad valorem taxation (in the absence of this Fee Agreement).

  • Maximum Daily Starts means the maximum number of times that a generating unit can be started in an Operating Day under normal operating conditions.

  • Gross weight means the aggregate weight of a vehicle or combination of vehicles and the load