Ex vivo definition

Ex vivo means outside of a living animal or human.
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Ex vivo delivery shall mean the introduction, outside of the body of a human, of such compositions into a cell, tissue, organoid, or organ, followed by the administration of the cell, tissue, organoid, or organ which contains such introduced compositions into the body of the same (autologous) or different (allogeneic) human, without limitation as to the formulation, anatomic site, or route of administration or the use of encapsulation or other devices for such administration. “In Vivo” delivery shall mean the introduction of such compositions into an individual, without limitation as to the formulation, anatomic site, or route of administration or the use of encapsulation or other devices for such administration.
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Ex vivo means that cells are extracted from a patient, corrected or otherwise modified by Gene Therapy, and transplanted or dosed back into patient.
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Examples of Ex vivo in a sentence

  • Ex vivo culture of circulating breast tumor cells for individualized testing of drug susceptibility.

  • Ex vivo generation of fully mature human red blood cells from hematopoietic stem cells.

  • Ex vivo expanded human regulatory T cells can prolong survival of a human islet allograft in a humanized mouse model.

  • Ex vivo programmed cell death and the prediction of response to chemotherapy.

  • Ex vivo identification, isolation and analysis of tumor-cytolytic T cells.

  • Ex vivo embryos (those not in a uterus) are not considered “human subjects” for these purposes, though federally funded research on them is regulated by the Dickey Amendment as described above.

  • Ex vivo surface and mechanical properties of coated orthodontic archwires.

  • Ex vivo culture of primary human fallopian tube epithelial cells.

  • Ex vivo 3D diffusion tensor imaging and quantification of cardiac laminar structure.

  • Ex vivo expansion and subsequent infusion of human bone marrow-derived stromal progenitor cells (mesenchymal progenitor cells): implications for therapeutic use.


More Definitions of Ex vivo

Ex vivo specifically means where the cells or tissue are removed from a healthy donor (in the case of allogeneic therapy) or the patient (in the case of autologous therapy), modified ex vivo and then, implanted, transplanted, infused, or transferred into the patient. For purposes of clarity, specifically excluded from these Fields of Use are the following:
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Ex vivo delivery shall mean the introduction, outside of the body of a human, of such compositions into a cell, tissue, organoid, or organ, followed by the administration of cell, tissue, organoid, or organ which contains such introduced compositions into the body of the same (autologous) or different (allogeneic) human, without limitation as to the formulation, anatomic site, or route of administration or the use of encapsulation or other devices for such administration, and (ii) "In Vivo" delivery shall mean the introduction of such compositions into an individual, without limitation as to the formulation, anatomic site, or route of administration or the use of encapsulation or other devices for such administration. "Licensed Product(s)" shall mean [*] Licensed Products and [*] Licensed Products. "[*] Licensed Product" shall mean [*] of a Designated Protein, the making, using, selling, offering for sale or import of which is covered by a claim in the Patent Rights. "[*] Licensed Product" shall mean [*], the making, using, selling, offering for sale or import of which is covered by a claim in the Patent Rights. For clarity, the term "Licensed Product(s)" does not include a composition that includes a protein that is covered by, or that was made by a process covered by, a claim in the Patent Rights, if that protein is not a Designated Protein.
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Ex vivo means outside of a living animal.
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Ex vivo means a biological process or reaction taking place outside of a living cell or organism;
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Ex vivo means that cells are extracted from a patient, corrected or otherwise modified by Gene Therapy, and transplanted or dosed
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