0001437749-24-007753 Sample Contracts

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Amendment #2 to Manufacturing and Supply Agreement
And Supply Agreement • March 14th, 2024 • UroGen Pharma Ltd. • Pharmaceutical preparations

This Amendment #2 to the Manufacturing & Supply Agreement (“Amendment #2”), effective as off its date of last signature (“Amendment #2 Effective Date”), is by and between UroGen Pharma Ltd., a company organized and existing under the laws of the State of Israel having an address at 9 HaTaasia St., Ra’anana 4365007, Israel (“Customer”) and Cenexi-Laboratoires Thissen S.A., a company incorporated in Belgium,having its registered office at 2-4-6, Rue de la Papyrée, B-1420 Braine-l'Alleud, also acting hereunder on behalf of its Affiliates ("Manufacturer").

LICENSE and SUPPLY AGREEMENT
License and Supply Agreement • March 14th, 2024 • UroGen Pharma Ltd. • Pharmaceutical preparations • Zürich

This License and Supply Agreement (the “Agreement”) shall enter into force upon the latter date of signature of the Agreement (the “Effective Date”) by and

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