0001193125-17-206488 Sample Contracts

AILERON THERAPEUTICS, INC. (a Delaware corporation) [●] Shares of Common Stock UNDERWRITING AGREEMENT
Underwriting Agreement • June 19th, 2017 • Aileron Therapeutics Inc • Pharmaceutical preparations • New York
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INDEMNIFICATION AGREEMENT
Indemnification Agreement • June 19th, 2017 • Aileron Therapeutics Inc • Pharmaceutical preparations • Delaware

This Indemnification Agreement (“Agreement”) is made as of [•], 2017 by and between Aileron Therapeutics, Inc., a Delaware corporation (the “Company”), and [•] (the “Indemnitee”). This Agreement supersedes and replaces any and all previous Agreements between the Company and Indemnitee covering the subject matter of this Agreement.

AILERON THERAPEUTICS, INC. EMPLOYMENT AGREEMENT
Employment Agreement • June 19th, 2017 • Aileron Therapeutics Inc • Pharmaceutical preparations • Massachusetts

This EMPLOYMENT AGREEMENT (the “Agreement”) is made and entered into by and between Aileron Therapeutics, Inc., a Delaware corporation (the “Company”) and Donald Dougherty of Boston, MA (the “Executive”).

Confidential Materials omitted and filed separately with the Securities and Exchange Commission. Double asterisks denote omissions. AMENDED AND RESTATED LICENSE AGREEMENT
License Agreement • June 19th, 2017 • Aileron Therapeutics Inc • Pharmaceutical preparations • Massachusetts

This Amended and Restated License Agreement (this “Agreement”) is entered into as of the 19th day of February, 2010 (the “Effective Date”), for the purpose of amending and replacing the License Agreement dated August 2, 2006 (the “Original Agreement”), by and among: Aileron Therapeutics, Inc. (formerly Renegade Therapeutics, Inc.), a Delaware corporation, having a principal place of business at 840 Memorial Drive, 2nd Floor, Cambridge, MA 02142 (“Licensee”); President and Fellows of Harvard College, Holyoke Center, Suite 727, 1350 Massachusetts Ave., Cambridge, MA (“Harvard”); and Dana-Farber Cancer Institute, Inc., 44 Binney Street, Boston, MA (“DFCI”). Harvard and DFCI shall be referred to together as “Licensors”.

AILERON THERAPEUTICS, INC. NONSTATUTORY STOCK OPTION AGREEMENT
Nonstatutory Stock Option Agreement • June 19th, 2017 • Aileron Therapeutics Inc • Pharmaceutical preparations

This option satisfies in full all commitments that the Company has to the Participant with respect to the issuance of stock, stock options or other equity securities.

AILERON THERAPEUTICS, INC. INCENTIVE STOCK OPTION AGREEMENT
Incentive Stock Option Agreement • June 19th, 2017 • Aileron Therapeutics Inc • Pharmaceutical preparations

This option satisfies in full all commitments that the Company has to the Participant with respect to the issuance of stock, stock options or other equity securities.

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