0001193125-08-224165 Sample Contracts

AMENDMENT NO. 1 TO LICENSE AGREEMENT
License Agreement • November 4th, 2008 • Durect Corp • Pharmaceutical preparations

This Amendment No. 1 to License Agreement (“Amendment No. 1”) is entered into as of September 12, 2008 and effective on the Amendment Date (defined below) by and between DURECT Corporation (“Durect”) and EpiCept Corporation (“EpiCept”).

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Contract
Development and License Agreement • November 4th, 2008 • Durect Corp • Pharmaceutical preparations • New York

Confidential treatment has been requested for portions of this exhibit. The copy filed herewith omits the information subject to the confidential treatment request. Omissions are designated as * * *. A complete version of this exhibit has been filed separately with the Securities and Exchange Commission.

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