0001193125-05-139830 Sample Contracts

LICENSE AGREEMENT Among COLEY PHARMACEUTICAL GROUP, INC. COLEY PHARMACEUTICAL GROUP, LTD. COLEY PHARMACEUTICAL GmbH and PFIZER INC.
License Agreement • July 11th, 2005 • Coley Pharmaceutical Group, Inc. • Pharmaceutical preparations • New York

Portions of this Exhibit were omitted and have been filed separately with the Secretary of the Commission pursuant to the Company’s application requesting confidential treatment under Rule 406 of the Securities Act.

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THIS INDENTURE made this 26th day of June, 2002
Indemnity Agreement • July 11th, 2005 • Coley Pharmaceutical Group, Inc. • Pharmaceutical preparations • Ontario

WITNESSETH that in consideration of the rents, covenants, conditions and agreements herein contained, the Landlord and the Tenant covenant and agree as follows:

NON-EXCLUSIVE LICENSE AGREEMENT
Non-Exclusive License Agreement • July 11th, 2005 • Coley Pharmaceutical Group, Inc. • Pharmaceutical preparations • Massachusetts

This NON-EXCLUSIVE LICENSE AGREEMENT (this “Agreement”), effective as of December 22, 2003 (the “Effective Date”), is between Coley Pharmaceutical Group, Inc., a Delaware corporation located at 93 Worcester Street, Suite 101, Wellesley, Massachusetts 02481 (“Coley”), and Chiron Corporation., a Delaware corporation having a principal place of business at 4560 Horton Street, Emeryville, California 94608 (“Licensee”) (each, a “Party” and collectively, the “Parties”).

STOCK PURCHASE AGREEMENT
Stock Purchase Agreement • July 11th, 2005 • Coley Pharmaceutical Group, Inc. • Pharmaceutical preparations • Delaware

THIS AGREEMENT, dated as of March 16, 2005, is between PFIZER INC., a Delaware corporation having a place of business at 235 East 42nd Street, New York, New York 10017-5755 (the “Purchaser”), and COLEY PHARMACEUTICAL GROUP, INC. (the “Company”), a Delaware corporation having a place of business at 93 Worcester Street, Wellesley, Massachusetts 02481.

LICENSE AGREEMENT
License Agreement • July 11th, 2005 • Coley Pharmaceutical Group, Inc. • Pharmaceutical preparations • Ontario

THIS AGREEMENT comes into force as of the first day of September, 1998, (“Effective Date”), by and between The Loeb Health Research Institute at the Ottawa Hospital (hereinafter referred to as “LOEB”) located at 725 Parkdale Avenue, Ottawa, Ontario K1 Y 4E9, CANADA and CpG ImmunoPharmaceuticals, Inc. having an address of 55 William Street, Suite 120, Wellesley, MA 02481, USA (hereinafter referred to as “CpG”).

SCREENING AND EVALUATION AGREEMENT BETWEEN PFIZER INC. AND COLEY PHARMACEUTICAL GROUP, INC.
Screening and Evaluation Agreement • July 11th, 2005 • Coley Pharmaceutical Group, Inc. • Pharmaceutical preparations

Portions of this Exhibit were omitted and have been filed separately with the Secretary of the Commission pursuant to the Company’s application requesting confidential treatment under Rule 406 of the Securities Act.

CONFIDENTIAL Coley Pharmaceutical Group, Inc. Wellesley Gateway Wellesley, Massachusetts 02481 September 25, 2001
License Agreement • July 11th, 2005 • Coley Pharmaceutical Group, Inc. • Pharmaceutical preparations • Massachusetts

This letter will serve as an amendment (the “Amendment”) to the License Agreement (the “Agreement”) dated as of September 1, 1998 between Coley Pharmaceutical Group, Inc., formerly known as CpG ImmunoPharmaceuticals, Inc. (“Coley”), and the Loeb Health Research Institute at the Ottawa Hospital (the “LOEB”). The Ottawa Health Research Institute (the “OHRI”) is the successor in interest to, and assignee of, all the rights and obligations of the LOEB under the Agreement. All capitalized terms that are used in this letter and not defined herein shall have the meanings ascribed to them in the Agreement. Except as specifically modified by this Amendment, the parties hereto agree that all of the terms and conditions set forth in the Agreement remain in full force and effect.

AWARD/CONTRACT 1. THIS CONTRACT IS A RATED ORDER UNDER DPAS (15 CFR 350) RATING PAGE Of PAGES COLEY PHARMACEUTICALS 93 WORCESTER ST WELLESLEY MA 02481-3609 9. DISCOUNT FOR PROMPT PAYMENT N/A CODE 38G55 FACILITY CODE 15A. ITEM NO. 15B. SUPPLIES/...
Coley Pharmaceutical Group, Inc. • July 11th, 2005 • Pharmaceutical preparations

The final price of this contract shall be the total of all costs determined reimbursable in accordance with the general provision of the contract entitled’ “Allowable Cost and Payment” but not exceeding the estimated cost plus the fixed fee, if any, both of which are specified above.

CONFIDENTIAL STRATEGIC ALLIANCE: LICENSE AGREEMENT INFECTIOUS DISEASES
Strategic Alliance: License Agreement • July 11th, 2005 • Coley Pharmaceutical Group, Inc. • Pharmaceutical preparations • New York

This License Agreement (“Agreement”) is made effective as of the 18th day of December 1998 (“Effective Date”), by and between CPG IMMUNOPHARMACEUTICALS, Inc. having a place of business at 55 William Street, Suite 120, Wellesley, MA, 02481, USA (herein referred to as “CPG”) and SMITHKLINE BEECHAM PLC., a corporation located at New Horizons Court, Brentford, Middlesex TW89EP, United Kingdom (herein referred to as “SB”)

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