EXHIBIT 10.18 SIGNAL PHARMACEUTICALS, INC. SERIES E PREFERRED STOCK PURCHASE AGREEMENT SEPTEMBER 9, 1997 TABLE OF CONTENTSStock Purchase Agreement • May 15th, 1998 • Signal Pharmaceuticals Inc • California
LEASE SUITE 100 FromSignal Pharmaceuticals Inc • May 15th, 1998 • California
EXHIBIT 10.16 THIS WARRANT AND THE SHARES ISSUABLE HEREUNDER HAS NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED OR ANY STATE SECURITIES LAWS. NO SALE OR DISPOSITION MAY BE EFFECTED WITHOUT (i) EFFECTIVE REGISTRATION STATEMENTS...Signal Pharmaceuticals Inc • May 15th, 1998 • California
1 EXHIBIT 10.15 LOAN AND SECURITY AGREEMENT Agreement No. 30433 Dated as of November 22, 1996Loan and Security Agreement • May 15th, 1998 • Signal Pharmaceuticals Inc • California
1 EXHIBIT 10.40 STOCK PURCHASE AGREEMENT THIS STOCK PURCHASE AGREEMENT is entered into as of March 31, 1996, by and between Signal Pharmaceuticals, Inc., a California corporation, (the "Company"), and Tanabe Seiyaku Co., Ltd., a Japanese corporation...Stock Purchase Agreement • May 15th, 1998 • Signal Pharmaceuticals Inc • California
1. 2 Bylaws and the Code, as the same may be amended from time to time (but, only to the extent that such amendment permits the Company to provide broader indemnification rights than the Bylaws or the Code permitted prior to adoption of such amendment).Indemnity Agreement • May 15th, 1998 • Signal Pharmaceuticals Inc • Delaware
BACKGROUNDLicense Agreement • May 15th, 1998 • Signal Pharmaceuticals Inc
DUPONT LOGO] MASTER LEASE AGREEMENT Dated and effective as of July 8, 1993 ("Effective Date"), this MASTER LEASE AGREEMENT ("Agreement") is entered into by and between E.I. Dupont de Nemours & Co., a Delaware corporation with offices at Barley Mill...Master Lease Agreement • May 15th, 1998 • Signal Pharmaceuticals Inc
EXHIBIT 10.32 EXCLUSIVE LICENSE AGREEMENTLicense Agreement • May 15th, 1998 • Signal Pharmaceuticals Inc • California
EXHIBIT 10.35 RESTRICTED STOCK PURCHASE AGREEMENT Agreement made as of this 26th day of October, 1993 by and between Signal Pharmaceuticals, Inc., a California corporation (the "Company"), and The Regents of the University of California ("The Regents"...Restricted Stock Purchase Agreement • May 15th, 1998 • Signal Pharmaceuticals Inc • California
1. 3 STOCK OPTION AGREEMENTSignal Pharmaceuticals Inc • May 15th, 1998
EXHIBIT 10.14 SIGNAL PHARMACEUTICALS, INC. AMENDMENT TO AMENDED AND RESTATED INVESTORS' RIGHTS AGREEMENT THIS AMENDMENT TO AMENDED AND RESTATED INVESTORS' RIGHTS AGREEMENT (the "Amendment") is entered into as of November 25, 1997, by and among SIGNAL...Investors' Rights Agreement • May 15th, 1998 • Signal Pharmaceuticals Inc • California
AGREEMENTAgreement • May 15th, 1998 • Signal Pharmaceuticals Inc • Delaware
EXHIBIT 10.1 SECOND AMENDED AND RESTATED VOTING AGREEMENT THIS AMENDED AND RESTATED VOTING AGREEMENT is made as of the th day of September, 1994, by and among SIGNAL PHARMACEUTICALS, INC., a California corporation (the "Company"), Accel IV L.P., Accel...Voting Agreement • May 15th, 1998 • Signal Pharmaceuticals Inc • California
LICENSE AGREEMENT BETWEEN SIGNAL PHARMACEUTICALS, INC. AND THE REGENTS OF THE UNIVERSITY OF CALIFORNIA Case No. [***]License Agreement • May 15th, 1998 • Signal Pharmaceuticals Inc • California
BETWEENCollaboration Agreement • May 15th, 1998 • Signal Pharmaceuticals Inc • California
ARES TRADING S.A. 2 RESEARCH, DEVELOPMENT AND LICENSE AGREEMENT ------------------------------------------- TABLE OF CONTENTS -----------------Development and License Agreement • May 15th, 1998 • Signal Pharmaceuticals Inc • Massachusetts
RECITALSLicense Agreement • May 15th, 1998 • Signal Pharmaceuticals Inc • Massachusetts
EXHIBIT 10.11 [SIGNAL LETTERHEAD LOGO] September 8, 1994 Oxford Bioscience Partners L.P., Oxford Bioscience Partners (Bermuda) Limited Partnership, Oxford Bioscience Partners (Adjunct) L.P. 650 Town Center Drive Suite 810 Costa Mesa, CA 92626 Re:...1 • May 15th, 1998 • Signal Pharmaceuticals Inc
RECITALSSecurity Agreement • May 15th, 1998 • Signal Pharmaceuticals Inc • California
EXHIBIT 10.49 COLLABORATIVE RESEARCH AND LICENSE AGREEMENTAnd License Agreement • May 15th, 1998 • Signal Pharmaceuticals Inc • Delaware
ARTICLE 1 DEFINITIONSResearch Collaboration Agreement • May 15th, 1998 • Signal Pharmaceuticals Inc • California
EXHIBIT 10.19 SIGNAL PHARMACEUTICALS, INC. SERIES F PREFERRED STOCK PURCHASE AGREEMENT NOVEMBER 25, 1997 TABLE OF CONTENTSStock Purchase Agreement • May 15th, 1998 • Signal Pharmaceuticals Inc • California
EXHIBIT 10.37 RESTRICTED STOCK PURCHASE AGREEMENT Agreement made as of this ______ day of ________________, 1998 by and between Signal Pharmaceuticals, Inc., a California corporation (the "Company"), and The Regents of the University of California...Restricted Stock Purchase Agreement • May 15th, 1998 • Signal Pharmaceuticals Inc • California
2- 3 liabilities, costs and expenses, including reasonable attorneys' fees, incurred by Lessor arising out of any purchase orders or assignments executed by Lessor with respect to any Equipment or services relating thereto.Master Equipment Lease • May 15th, 1998 • Signal Pharmaceuticals Inc • California
BETWEENStock Purchase Agreement • May 15th, 1998 • Signal Pharmaceuticals Inc • California
EXHIBIT 10.47 RESTRICTED STOCK PURCHASE AGREEMENT Agreement made as of this 8th day of December, 1997 by and between Signal Pharmaceuticals, Inc., a California corporation (the "Company"), and University of Massachusetts (the "Purchaser"). Unless...Restricted Stock Purchase Agreement • May 15th, 1998 • Signal Pharmaceuticals Inc • California
CUSTOMER NO. 1093 MASTER LEASE AGREEMENT Lessor: TRANSAMERICA BUSINESS CREDIT CORPORATION RIVERWAY II WEST OFFICE TOWER WEST HIGGINS ROSEMONT, ILLINOIS 60018 Lessee: SIGNAL PHARMACEUTICALS, INC. 5555 OBERLIN DRIVE SAN DIEGO, CALIFORNIA 92121 The...Master Lease Agreement • May 15th, 1998 • Signal Pharmaceuticals Inc • Illinois
AGREEMENT AMONGCollaborative Development and Licensing Agreement • May 15th, 1998 • Signal Pharmaceuticals Inc • California
EXHIBIT 10.45 RESTRICTED STOCK PURCHASE AGREEMENT Agreement made as of this 31st day of October, 1996 by and between Signal Pharmaceuticals, Inc., a California corporation (the "Company"), and University of Massachusetts (or "Purchaser"). Unless...Restricted Stock Purchase Agreement • May 15th, 1998 • Signal Pharmaceuticals Inc • California
1 EXHIBIT 10.26 SIGNAL PHARMACEUTICALS CONSULTING AGREEMENT This CONSULTING AGREEMENT (the "Agreement") is made as of April 1, 1996 (the "Effective Date") by and between Signal Pharmaceuticals, Inc., a California corporation (the "Company"), and John...Signal Pharmaceuticals Consulting Agreement • May 15th, 1998 • Signal Pharmaceuticals Inc • California
1 EXHIBIT 10.9 [SIGNAL PHARMACEUTICALS, INC. LETTERHEAD] September 6, 1994 U.S. Venture Partners IV, L.P. 2180 Sandhill Road, Suite #300 Menlo Park, Ca Re: MANAGEMENT RIGHTS Gentlemen: This letter will confirm our agreement that pursuant to your...Signal Pharmaceuticals Inc • May 15th, 1998
1 EXHIBIT 10.10 [SIGNAL LOGO] September 8, 1994 U.S. Venture Partners IV, L.P. Second Ventures II, L.P. USVP Entrepreneur Partners II, L.P. 2180 Sand Hill Road Suite 300 Menlo Park, CA 94025 Attn: Philip Young Re: Management Rights Ladies and...Signal Pharmaceuticals Inc • May 15th, 1998
1 EXHIBIT 10.12 September 5, 1997 U.S. Venture Partners IV, L.P. 2180 Sand Hill Road, Suite #300 Menlo Park, Ca 94025 RE: MANAGEMENT RIGHTS Gentlemen: This letter will confirm our agreement that pursuant to your purchase of 45,733 shares of Series E...Signal Pharmaceuticals Inc • May 15th, 1998
June 13, 1995 Carl. F. Bobkowski P.O. Box 9664 Rancho Santa Fe, CA 92067 Dear Carl: It is my pleasure to offer you the position of Executive Vice President at Signal Pharmaceuticals, Inc. This letter ("Letter Agreement") will serve to confirm the...Signal Pharmaceuticals Inc • May 15th, 1998
