EXHIBIT 10.105
AGREEMENT
THIS AGREEMENT is made and entered into this 8th day of January, 1996,
by and between the CLINIMETRICS RESEARCH ASSOCIATES, INC., a California
corporation with offices located at 0000 Xxxxxxx Xxxxx, Xxxxx 000, Xxx Xxxx, XX
00000 (hereinafter "CRA") and BIOMUNE SYSTEMS, INC. with offices located at 000
Xxxxxxx Xxxxx, Xxxxx 000, Xxxx Xxxx Xxxx, XX 00000 (hereinafter "CLIENT").
RECITALS
WHEREAS, CRA is the business of providing clinical research development and
other related services; and
WHEREAS, CLIENT is in the business of developing thereapeutic agents which
utilizes services such as those offered by CRA.
NOW THEREFORE, the parties agree as follows:
AGREEMENTS
Services Performed
1. In consideration of the compensation hereinafter provided for, CRA shall
perform the following services for Client: clinical trial design and
implementation, clinical trial monitoring, site management, data analysis and
reporting, and other related services as requested by Client.
It is expected that CRA will perform services at its place of business and
at Client's place of business, as necessary. CRA will comply with Client's
Standard Operating Procedures and work under the direction of Client's
personnel.
Compensation
2. For performing the above-stated services CRA shall be compensated by
Client as follows (refer to APPENDIX A for cost estimates):
a) Client shall pay an hourly rate of $65 per hour for protocol
development, case report form design, site recruitment and management
services.
b) Site monitoring services performed by, if travel of more than 50
miles from CRA's place of business is required, shall be paid by Client to
CRA at the per diem rate of $520 per day plus expenses as set forth in
paragraph 7 hereinunder. If travel requires transit of greater than or
equal to 1,000 miles, CRA shall be compensated one full travel day by
Client at the per diem rate of $520. Only one travel day will be paid per
contiguous trip. For the purposes of this section per diem will be defined
as any services performed on any given calendar date regardless of the
number of hours.
c) Client shall pay an hourly rate of $35 per hour for data entry and
data management services.
d) Client shall pay an hourly rate of $80 per hour for database
development and programming services.
e) Client shall pay an hourly rate of $125 per hour for statistical
analysis and reporting services.
f) Client shall reimburse CRA for the cost of producing case report
forms and study manuals.
g) Client shall make all payments to CRA in accordance with paragraphs
(a), (b), (c), (d), (e), and (f) within thirty days of receipt of an
invoice from CRA itemizing the number of work days or a fractional part
thereof on which services were rendered and associated expenses. All
payments are to be made to CRA in Santa Xxxxx County, California, or as
directed by CRA.
Hiring of CRA's Employees
3. In the event Client hires any of CRA's employees without the prior
written approval of CRA, Client shall pay to CRA a sum equivalent to one third
of such employee's annual salary at the time of his/her termination of
employment at CRA.
Indemnification
4. CRA shall perform its services in accordance with Client's standard
operating procedures and under the direction of Client's personnel services.
Therefore, Client shall indemnify and hold CRA harmless from any and all
liability which may result to Client and third parties as a direct result of the
performance of services by CRA for Client under the terms of this Agreement.
Inventions
5. To the extent that CRA is not precluded from doing so by a preexisting
contract, and if , during any period of CRA's service or as a result of such
service, CRA conceives, makes, or develops any inventions relating in any way to
Client's business or that of its subsidiaries or affiliates, CRA will (a) give
notice thereof to Client; (b) assign to Client all of CRA's rights therein; and
(c) execute any necessary papers and otherwise reasonably cooperate with Client
in securing of patents on such inventions.
Confidentiality/Non-Disclosure
6. CRA shall, both during and subsequent to CRA's services, keep
confidential any technical or other information of a confidential nature,
including knowledge of our projects and general activities and any information
not publicly disclosed relating to business which CRA may acquire through CRA's
consulting activities or otherwise. CRA will not disclose such information in
any matter without Client's express written permission. Title to all property
involved shall remain exclusively in Client. Upon termination of services, or
upon request at any time, CRA shall account for, and return to Client all papers
containing any such confidential information.
Travel Expenses
7. Client shall reimburse CRA for reasonable travel and living expenses for
its employees incurred in connection with work performed by CRA in accordance
with this Agreement. Reimbursements shall include but are not limited to
airfare, lodging, meals, tips, car rental, telephone, postage and automobile
mileage.
Limitation of Authority
8. CRA and Client are, and shall at all times be, independent contractors.
Neither party is a partner, employer, co-venturer or employee of the other, and
neither shall represent to any third party anything to the contrary.
a) Without limiting the foregoing, neither party shall have the
authority whatsoever to execute any agreement on behalf of the other party, nor
shall either party have any authority to negotiate any such agreement except as
the other party may expressly direct in writing. Each party shall be responsible
for meeting the tax requirements and Worker's Compensation for its own
employees.
b) It is agreed that CRA is to have complete freedom of action to the
details, methods, and means of performing these services. It is further
understood that CRA is retained and has contracted with Client only for the
purposes and to the extent set forth in this Agreement, and CRA's relation to
Client and any of its subsidiary companies shall, during the period of CRA's
retainer and services, be that of an independent contractor, and CRA shall be
free to dispose of such portion of CRA's entire time, energy, and skill as CRA
is not obligated to devote to Client and its subsidiaries, in such manner as CRA
sees fit and to such persons, firms, or corporations as CRA deems advisable so
long as same does not create a conflict of interest between Client and such
other persons, firms or corporations.
Term and Termination
9. a) The term of this Agreement shall commence upon the date set forth
above and shall continue hereafter for a renewable period of one (1) year unless
and may be renewed for additional one year periods by either party upon issuance
of thirty (30) days prior written notice to the other party. In addition, either
party hereto shall, without further notice have the immediate right to terminate
this Agreement if any of the following events or conditions occur:
i) A petition for bankruptcy is filed by or against either party
hereto which is not discharged within sixty (60) days;
ii) A default by the other party hereto in the performance of any
of the material obligations under the terms of this Agreement is not
cured within thirty (30) days of such parties receipt of written
notice of such default;
iii) Upon assignment of this Agreement to a third party by
Client;
b) Notice of continuation of the Agreement for additional one-year
(twelve-month) periods shall be given by Client to CRA at least two (2) months
prior to the end of the current one-year period. Compensation may be modified or
additional consideration given by mutual agreement of the parties.
Attorney's Fees
10. In the event of any litigation or arbitration between the parties
arising from this Agreement, the prevailing party shall be entitled to recover,
in addition to any other relief granted or awarded, its reasonable costs and
expenses (including attorney's fees) incurred.
Governing Law
11. This Agreement shall be governed and interpreted in accordance with the
laws of the State of California. The parties agree that any litigation for
injunctive relief shall be resolved in the state or federal courts within Santa
Xxxxx County, California.
Force Majeure
12. Neither party shall be deemed in default of this Agreement to the
extent that performance of their obligations or attempts to cure any breach are
delayed or prevented by reason of any act of God, fire, natural disaster,
accident, act of government, shortages of material or supplies or any other
cause beyond the control of such party ("Force Majeure"), provided that such
party gives the other party written notice thereof promptly, and, in any event,
within fifteen (15) days of discovery thereof and uses its best effort to cure
the breach. In the event of such a Force Majeure, the time for performance of
cure shall be extended for a period equal to the duration of the Force Majeure
but not in excess of two (2) months.
Severability
13. Should any provision of this Agreement be held void, invalid or
inoperative, the remaining provision of this Agreement shall not be affected and
shall continue in effect as though such provisions were deleted.
Notice
14. Any notice required or permitted to be sent hereunder shall be in
writing and shall be sent to either party at the address listed above for such
party, or such other addresses which either party may so notify the other. In
the event notice is sent pursuant to the terms set forth hereinabove, then such
notice shall be deemed delivered if hand delivered or if mailed postage prepaid
by registered or certified mail return receipt requested. All other notices
shall be deemed delivered if mailed postage prepaid by first class mail.
Entire Agreement
15. This Agreement states the entire Agreement between the parties with
respect to the subject hereof and supersedes all prior negotiations,
understanding, and agreements between the parties hereto concerning the subject
matter hereof. No amendment or modification of this Agreement shall be made
except by an instrument in writing signed by both parties.
CLINIMETRICS RESEARCH ASSOCIATES, INC.
By: /s/ [illegible]
Title: President
Date: January 8, 1996
Federal Tax I.D. No.: 00-0000000
BIOMUNE SYSTEMS, INC.
By: /s/ Xxxxx X. Xxxxxxx
Title: Chief Executive Officer
As agent for Optim Nutrition, Inc.
APPENDIX A
HOURS $/HOUR TOTAL
LABOR
Protocol Development 60 65 3,900
Case Report Form Design 40 65 2,600
Site Recruitment/Mgnt. 20 65 1,300
Site Monitoring 96 65 6,240
Data Management/Entry 260 35 9,100
Programming 80 80 6,400
Analysis 100 125 12,500
Labor Sub-Total 42.040
DAYS $/DAY TOTAL
TRAVEL
Site Visits 10 400 4,000
Development Meetings 1 800 800
Travel Sub-Total $4,800
QUANTITY $/UNIT TOTAL
STUDY SUPPLIES
Case Report Forms 50 30/ea 1,500
Study Manuals 10 20/ea 200
S/E Sub-Total $1,700
Subtotal 48,540
Administrative Fee (10%) 4,854
TOTAL $53,394