Medicines Co /De Sample Contracts

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R E C I T A L S
Stockholders' Agreement • May 19th, 2000 • Medicines Co/ Ma • Delaware
LEASE FROM:
Lease • March 5th, 2003 • Medicines Co /De • Pharmaceutical preparations
LEASE FROM:
Agreement • March 5th, 2004 • Medicines Co /De • Pharmaceutical preparations
FROM
Medicines Co/ Ma • May 19th, 2000 • Massachusetts
RECITALS
Loan and Security Agreement • May 15th, 2002 • Medicines Co/ Ma • Pharmaceutical preparations • California
Contract
Medicines Co /De • June 28th, 2019 • Pharmaceutical preparations • New York
THE MEDICINES COMPANY AND WELLS FARGO BANK, NATIONAL ASSOCIATION, as Trustee INDENTURE Dated as of December 18, 2018 3.50% Convertible Senior Notes due 2024
Indenture • December 18th, 2018 • Medicines Co /De • Pharmaceutical preparations • New York

INDENTURE dated as of December 18, 2018 between THE MEDICINES COMPANY, a Delaware corporation, as issuer (the “Company”, as more fully set forth in Section 1.01) and WELLS FARGO BANK, NATIONAL ASSOCIATION, a national banking association, as trustee (the “Trustee”, as more fully set forth in Section 1.01).

1 THE MEDICINES COMPANY 5,000,000 Shares of Common Stock Underwriting Agreement
Medicines Co/ Ma • July 21st, 2000 • Pharmaceutical preparations • New York
AND
Medicines Co /De • August 5th, 2003 • Pharmaceutical preparations
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BACKGROUND:
Master Services Agreement • February 23rd, 2001 • Medicines Co/ Ma • Pharmaceutical preparations • New Jersey
INDEMNITY AGREEMENT
Indemnity Agreement • December 23rd, 2015 • Medicines Co /De • Pharmaceutical preparations • Delaware

THIS INDEMNITY AGREEMENT (this “Agreement”) is made as of , 2015, by and between The Medicines Company, a Delaware corporation (the “Company”), and (“Indemnitee”).

August 17, 2006 [Name] [Title] The Medicines Company 8 Campus Drive Parsippany, NJ 07054 Dear [Name]:
Medicines Co /De • March 1st, 2007 • Pharmaceutical preparations

This letter agreement amends and restates in its entirety the letter agreement between you and The Medicines Company (the “Company”) dated December 21, 2005 regarding the subject matter hereof.

Confidential Materials omitted and filed separately with the Securities and Exchange Commission. Double asterisks denote omissions. AGREEMENT AND PLAN OF MERGER by and among THE MEDICINES COMPANY, SILVER SURFER ACQUISITION CORP., FORTIS ADVISORS LLC...
Agreement and Plan of Merger • January 10th, 2013 • Medicines Co /De • Pharmaceutical preparations • Delaware

THIS AGREEMENT AND PLAN OF MERGER (this “Agreement”) is entered into as of December 11, 2012, by and among The Medicines Company, a Delaware corporation (the “Buyer”), Silver Surfer Acquisition Corp., a Delaware corporation and a wholly owned subsidiary of the Buyer (the “Transitory Subsidiary”), Fortis Advisors LLC, a Delaware limited liability company, solely in its capacity as the Representative (the “Representative”), and Incline Therapeutics, Inc., a Delaware corporation (the “Company”). The Buyer, the Transitory Subsidiary, the Company and the Representative are sometimes referred to herein individually as a “Party” and collectively as the “Parties”. All capitalized terms used in this Agreement shall have the meanings given to them in Section 9.1.

Mark Timney BY HAND/EMAIL December 10, 2018 Dear Mark,
Medicines Co /De • December 11th, 2018 • Pharmaceutical preparations

As an incentive to induce you to join The Medicines Company (the “Company”) as its Chief Executive Officer, the Company agrees, on the terms and subject to the conditions set forth in this letter (this “Agreement”), as follows:

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