Upfront Payments. Within ten (10) days of the Effective Date, Celgene shall pay Acceleron Twenty-Five Million U.S. Dollars ($25,000,000) as an upfront, non-creditable, nonrefundable fee, relating to the license grants set forth in Article 4.
Upfront Payments. Centogene will issue at the beginning of each calendar month, a preliminary invoice for a prorated amount of the Annual Flat Fee, i.e. an amount equal to 1/12 of each Annual Flat Fee. Shire International shall make payment within ten (10) Business Days upon receipt of a proper invoice.
Upfront Payments. PTI shall make the following payments specified below to DURECT within [* * *] days following achievement of the corresponding event: Event Payment
Upfront Payments. (a) Upfront payment. Following the Effective Date, in consideration of the rights granted to ARES TRADING hereunder, ARES TRADING shall pay to Intrexon a one-time, non-refundable, non-creditable upfront payment of one hundred and fifteen million Dollars ($115,000,000) within forty-five (45) days after receipt by ARES TRADING of a corresponding invoice. Payment of the upfront payment shall be subject to any withholding tax obligations set forth in Section 8.7.
Upfront Payments. In consideration of the rights granted to AstraZeneca under this Agreement and the investment incurred for HMPL-504 by Xxxxxxxxx prior to the date of this Agreement, AstraZeneca shall, upon receipt of an invoice, make a payment of Twenty Million Dollars ($20,000,000) on the Effective Date as an upfront, non-creditable, non-refundable fee to Xxxxxxxxx, and such fee will not be reduced by the amount of any Indirect Taxes or Withholding Taxes required to be paid by AstraZeneca under any Applicable Law, subject, however, to Section 5.8.2 and 5.8.3.
Upfront Payments. Within two (2) Business Days after the Effective Date, Jazz shall pay to Pfenex a one-time, non-refundable (i) upfront payment of [***] Dollars ($[***]) in consideration of the licenses and related rights granted under this Agreement for HemOnc-NextGen; and (ii) option payment of [***] Dollars ($[***]) in consideration of the Option granted under Section 2.4 (together, such amounts, the “Upfront Payments”).
Upfront Payments. In consideration of the licenses and rights granted hereunder, KHK shall pay $17,500,000 to Syndax within thirty (30) days after the Effective Date. Such fee shall be non-refundable and shall not be creditable against any other amount due to Syndax pursuant to this Agreement.
Upfront Payments. Upon signing of this Agreement, within five (5) Business Days Endo will pay via wire to Vyrix two hundred and fifty-thousand US Dollars ($USD 250,000).
Upfront Payments. Prior to the commencement of any GLP toxicity study for the first Licensed Product by Genocea, its Affiliates or a Sublicensee in each of the Non-Exclusive Disease Fields, Genocea shall pay to Isconova an upfront, non-creditable, non-refundable fee of [* * *]. For the avoidance of doubt, payments under this Section 6.2 shall only be payable by Genocea once for each unique Disease Field, irrespective of the number of Licensed Products in any given Disease Field that become the subject of a GLP toxicity study.
Upfront Payments. Forest shall make the following payments to Microbia: (i) Fifty Million Dollars ($50,000,000) within fifteen (15) days after the Effective Date as an upfront, non-creditable, non-refundable fee, and (ii) Twenty Million Dollars ($20,000,000) within ten (10) days following January 15, 2008 as a non-creditable, non-refundable license fee.
