Common use of Omnibus Signature Page Clause in Contracts

Omnibus Signature Page. This Subscription Agreement is intended to be read and construed in conjunction with the Warrant Agreement, the Security Agreement, the Note and the Warrant. Accordingly, pursuant to the terms and conditions of this Subscription Agreement and such related agreements it is hereby agreed that the execution by the Lender of this Subscription Agreement, in the place set forth herein, shall constitute agreement to be bound by the terms and conditions hereof and the terms and conditions of the Warrant Agreement and the Security Agreement (as amended pursuant to Section 6 of this Subscription Agreement), with the same effect as if each of such separate but related agreement were separately signed. VYTERIS HOLDINGS (NEVADA), INC. OMNIBUS SIGNATURE PAGE TO SUBSCRIPTION AGREEMENT, WARRANT AGREEMENT AND SECURITY AGREEMENT Date (NOTE: To be completed by subscriber): July 18, 2005 -------------------------------------------------------------------------------- If the Purchaser is an INDIVIDUAL, and if purchased as JOINT TENANTS, as TENANTS IN COMMON, or as COMMUNITY PROPERTY: ---------------------------- ------------------------------ PRINT NAME(S) SOCIAL SECURITY NUMBER(S) --------------------------- ------------------------------ SIGNATURE(S) OF SUBSCRIBER(S) SIGNATURE ---------------------------- ------------------------------ DATE ADDRESS If the Purchaser is a PARTNERSHIP, CORPORATION, LIMITED LIABILITY COMPANY or TRUST: XXXXXXX XXXXX SPECIALTY GROUP, LLC ---------------------------- ------------------------------ NAME OF PARTNERSHIP, FEDERAL TAXPAYER CORPORATION, LIMITED IDENTIFICATION NUMBER LIABILITY COMPANY OR TRUST BY: /s/ Xxxxxxx X. Xxxxxxxxx DELAWARE ------------------------- ------------------------------ NAME: XXXXXXX X. XXXXXXXXX STATE OF ORGANIZATION TITLE: 000 XXXXXXX XXXXXX, JULY 18, 2005 XXX XXXX, XX 00000 ---------------------------- ------------------------------ DATE ADDRESS VYTERIS HOLDINGS (NEVADA), INC. By: /s/ Xxxxxxx XxXxxxxxxx --------------------------- Name: Xxxxxxx XxXxxxxxxx Title: Vice President and Chief Financial Officer ACCREDITED INVESTOR CERTIFICATION Initial the appropriate item(s) THE UNDERSIGNED FURTHER REPRESENTS AND WARRANTS AS INDICATED BELOW BY THE UNDERSIGNED'S INITIALS:

Omnibus Signature Page. This Subscription Agreement is intended to be read and construed in conjunction with the Warrant Agreement, the Security Agreement, the Note and the Warrant. Accordingly, pursuant to the terms and conditions of this Subscription Agreement and such related agreements it is hereby agreed that the execution by the Lender of this Subscription Agreement, in the place set forth herein, shall constitute agreement to be bound by the terms and conditions hereof and the terms and conditions of the Warrant Agreement and the Security Agreement (as amended pursuant to Section 6 of this Subscription Agreement), with the same effect as if each of such separate but related agreement were separately signed. VYTERIS HOLDINGS (NEVADA), INC. OMNIBUS SIGNATURE PAGE TO SUBSCRIPTION AGREEMENT, WARRANT AGREEMENT AND SECURITY AGREEMENT Date (NOTE: To be completed by subscriber): July 18June 2, 2005 -------------------------------------------------------------------------------- If the Purchaser is an INDIVIDUAL, and if purchased as JOINT TENANTS, as TENANTS IN COMMON, or as COMMUNITY PROPERTY: ---------------------------- ------------------------------ PRINT NAME(S) SOCIAL SECURITY NUMBER(S) --------------------------- ------------------------------ SIGNATURE(S) OF SUBSCRIBER(S) SIGNATURE ---------------------------- ------------------------------ DATE ADDRESS If the Purchaser is a PARTNERSHIP, CORPORATION, LIMITED LIABILITY COMPANY or TRUST: XXXXXXX XXXXX SPECIALTY GROUPPRIVATE EQUITY ACCREDITED FUND III, LLC ---------------------------- ------------------------------ NAME OF PARTNERSHIP, FEDERAL TAXPAYER CORPORATION, LIMITED IDENTIFICATION NUMBER LIABILITY COMPANY OR TRUST BY: /s/ Xxxxxxx X. Xxxxxxxxx DELAWARE NEW YORK ------------------------- ------------------------------ NAME: XXXXXXX X. XXXXXXXXX STATE OF ORGANIZATION TITLE: 000 XXXXXXX XXXXXX, JULY 18JUNE 2, 2005 XXX XXXX, XX 00000 ---------------------------- ------------------------------ DATE ADDRESS VYTERIS HOLDINGS (NEVADA), INC. By: /s/ Xxxxxxx XxXxxxxxxx XxXxxxxx, Ph.D. --------------------------- Name: Xxxxxxx XxXxxxxxxx XxXxxxxx, Ph.D. Title: Vice President and Chief Financial Executive Officer ACCREDITED INVESTOR CERTIFICATION Initial the appropriate item(s) THE UNDERSIGNED FURTHER REPRESENTS AND WARRANTS AS INDICATED BELOW BY THE UNDERSIGNED'S INITIALS:

Omnibus Signature Page. This Subscription Agreement is intended to be read and construed in conjunction with the Warrant Agreement, the Security Agreement, the Note and the Warrant. Accordingly, pursuant to the terms and conditions of this Subscription Agreement and such related agreements it is hereby agreed that the execution by the Lender of this Subscription Agreement, in the place set forth herein, shall constitute agreement to be bound by the terms and conditions hereof and the terms and conditions of the Warrant Agreement and the Security Agreement (as amended pursuant to Section 6 of this Subscription Agreement), with the same effect as if each of such separate but related agreement were separately signed. VYTERIS HOLDINGS (NEVADA), INC. OMNIBUS SIGNATURE PAGE TO SUBSCRIPTION AGREEMENT, WARRANT AGREEMENT AND SECURITY AGREEMENT Date (NOTE: To be completed by subscriber): July 18May 27, 2005 -------------------------------------------------------------------------------- If the Purchaser is an INDIVIDUAL, and if purchased as JOINT TENANTS, as TENANTS IN COMMON, or as COMMUNITY PROPERTY: ---------------------------- ------------------------------ PRINT NAME(S) SOCIAL SECURITY NUMBER(S) --------------------------- ------------------------------ SIGNATURE(S) OF SUBSCRIBER(S) SIGNATURE ---------------------------- ------------------------------ DATE ADDRESS If the Purchaser is a PARTNERSHIP, CORPORATION, LIMITED LIABILITY COMPANY or TRUST: XXXXXXX XXXXX SPECIALTY GROUPPRIVATE EQUITY FUND I, LLC ---------------------------- ------------------------------ NAME OF PARTNERSHIP, FEDERAL TAXPAYER CORPORATION, LIMITED IDENTIFICATION NUMBER LIABILITY COMPANY OR TRUST BY: /s/ Xxxxxxx X. Xxxxxxxxx DELAWARE NEW YORK ------------------------- ------------------------------ NAME: XXXXXXX X. XXXXXXXXX STATE OF ORGANIZATION TITLE: 000 XXXXXXX XXXXXX, JULY 18May 27, 2005 XXX XXXX, XX 00000 ---------------------------- ------------------------------ DATE ADDRESS VYTERIS HOLDINGS (NEVADA), INC. By: /s/ Xxxxxxx XxXxxxxxxx --------------------------- XxXxxxxx -------------------- Name: Xxxxxxx XxXxxxxxxx XxXxxxxx, Ph.D. Title: Vice President and Chief Financial Executive Officer ACCREDITED INVESTOR CERTIFICATION Initial the appropriate item(s) THE UNDERSIGNED FURTHER REPRESENTS AND WARRANTS AS INDICATED BELOW BY THE UNDERSIGNED'S INITIALS:

Omnibus Signature Page. This Subscription Agreement is intended to be read and construed in conjunction with the Warrant Agreement, the Security Agreement, the Note and the Warrant. Accordingly, pursuant to the terms and conditions of this Subscription Agreement and such related agreements it is hereby agreed that the execution by the Lender of this Subscription Agreement, in the place set forth herein, shall constitute agreement to be bound by the terms and conditions hereof and the terms and conditions of the Warrant Agreement and the Security Agreement (as amended pursuant to Section 6 of this Subscription Agreement), with the same effect as if each of such separate but related agreement were separately signed. VYTERIS HOLDINGS (NEVADA), INC. OMNIBUS SIGNATURE PAGE TO SUBSCRIPTION AGREEMENT, WARRANT AGREEMENT AND SECURITY AGREEMENT Date (NOTE: To be completed by subscriber): July 18May 27, 2005 -------------------------------------------------------------------------------- If the Purchaser is an INDIVIDUAL, and if purchased as JOINT TENANTS, as TENANTS IN COMMON, or as COMMUNITY PROPERTY: ---------------------------- ------------------------------ PRINT NAME(S) SOCIAL SECURITY NUMBER(S) --------------------------- ------------------------------ SIGNATURE(S) OF SUBSCRIBER(S) SIGNATURE ---------------------------- ------------------------------ DATE ADDRESS If the Purchaser is a PARTNERSHIP, CORPORATION, LIMITED LIABILITY COMPANY or TRUST: XXXXXXX XXXXX SPECIALTY GROUP, LLC ---------------------------- ------------------------------ NAME OF PARTNERSHIP, FEDERAL TAXPAYER CORPORATION, LIMITED IDENTIFICATION NUMBER LIABILITY COMPANY OR TRUST BY: /s/ Xxxxxxx X. Xxxxxxxxx DELAWARE NEW YORK ------------------------- ------------------------------ NAME: XXXXXXX X. XXXXXXXXX STATE OF ORGANIZATION TITLE: 000 XXXXXXX XXXXXX, JULY 18May 27, 2005 XXX XXXX, XX 00000 ---------------------------- ------------------------------ DATE ADDRESS VYTERIS HOLDINGS (NEVADA), INC. By: /s/ Xxxxxxx XxXxxxxxxx --------------------------- XxXxxxxx -------------------- Name: Xxxxxxx XxXxxxxxxx XxXxxxxx, Ph.D. Title: Vice President and Chief Financial Executive Officer ACCREDITED INVESTOR CERTIFICATION Initial the appropriate item(s) THE UNDERSIGNED FURTHER REPRESENTS AND WARRANTS AS INDICATED BELOW BY THE UNDERSIGNED'S INITIALS:

Omnibus Signature Page. This Subscription Agreement is intended to be read and construed in conjunction with the Warrant Agreement, the Security Agreement, the Note and the Warrant. Accordingly, pursuant to the terms and conditions of this Subscription Agreement and such related agreements it is hereby agreed that the execution by the Lender of this Subscription Agreement, in the place set forth herein, shall constitute agreement to be bound by the terms and conditions hereof and the terms and conditions of the Warrant Agreement and the Security Agreement (as amended pursuant to Section 6 of this Subscription Agreement), with the same effect as if each of such separate but related agreement were separately signed. VYTERIS HOLDINGS (NEVADA), INC. OMNIBUS SIGNATURE PAGE TO SUBSCRIPTION AGREEMENT, WARRANT AGREEMENT AND SECURITY AGREEMENT Date (NOTE: To be completed by subscriber): July 18May 27, 2005 -------------------------------------------------------------------------------- If the Purchaser is an INDIVIDUAL, and if purchased as JOINT TENANTS, as TENANTS IN COMMON, or as COMMUNITY PROPERTY: ---------------------------- ------------------------------ PRINT NAME(S) SOCIAL SECURITY NUMBER(S) --------------------------- ---------------------------- ------------------------------ SIGNATURE(S) OF SUBSCRIBER(S) SIGNATURE ---------------------------- ------------------------------ DATE ADDRESS If the Purchaser is a PARTNERSHIP, CORPORATION, LIMITED LIABILITY COMPANY or TRUST: XXXXXXX XXXXX SPECIALTY GROUPILLUMINATION FUND, LLC ---------------------------- ------------------------------ NAME OF PARTNERSHIP, FEDERAL TAXPAYER CORPORATION, LIMITED IDENTIFICATION NUMBER LIABILITY COMPANY OR TRUST BY: /s/ Xxxxxxx X. Xxxxxxxxx DELAWARE NEW YORK ------------------------- ------------------------------ NAME: XXXXXXX X. XXXXXXXXX STATE OF ORGANIZATION TITLE: 000 XXXXXXX XXXXXX, JULY 18MAY 27, 2005 XXX XXXX, XX 00000 ---------------------------- ------------------------------ DATE ADDRESS VYTERIS HOLDINGS (NEVADA), INC. By: /s/ Xxxxxxx XxXxxxxxxx --------------------------- XxXxxxxx -------------------- Name: Xxxxxxx XxXxxxxxxx XxXxxxxx, Ph.D. Title: Vice President and Chief Financial Executive Officer ACCREDITED INVESTOR CERTIFICATION Initial the appropriate item(s) THE UNDERSIGNED FURTHER REPRESENTS AND WARRANTS AS INDICATED BELOW BY THE UNDERSIGNED'S INITIALS:

Omnibus Signature Page. This Subscription Agreement is intended to be read and construed in conjunction with the Warrant Agreement, the Security Agreement, the Note and the Warrant. Accordingly, pursuant to the terms and conditions of this Subscription Agreement and such related agreements it is hereby agreed that the execution by the Lender of this Subscription Agreement, in the place set forth herein, shall constitute agreement to be bound by the terms and conditions hereof and the terms and conditions of the Warrant Agreement and the Security Agreement (as amended pursuant to Section 6 of this Subscription Agreement), with the same effect as if each of such separate but related agreement were separately signed. VYTERIS HOLDINGS (NEVADA), INC. OMNIBUS SIGNATURE PAGE TO SUBSCRIPTION AGREEMENT, WARRANT AGREEMENT AND SECURITY AGREEMENT Date (NOTE: To be completed by subscriber): July 18May 27, 2005 -------------------------------------------------------------------------------- If the Purchaser is an INDIVIDUAL, and if purchased as JOINT TENANTS, as TENANTS IN COMMON, or as COMMUNITY PROPERTY: ---------------------------- ------------------------------ PRINT NAME(S) SOCIAL SECURITY NUMBER(S) --------------------------- ---------------------------- ------------------------------ SIGNATURE(S) OF SUBSCRIBER(S) SIGNATURE ---------------------------- ------------------------------ DATE ADDRESS If the Purchaser is a PARTNERSHIP, CORPORATION, LIMITED LIABILITY COMPANY or TRUST: XXXXXXX XXXXX SPECIALTY GROUPPRIVATE ACCREDITED EQUITY FUND III, LLC ---------------------------- ------------------------------ NAME OF PARTNERSHIP, FEDERAL TAXPAYER CORPORATION, LIMITED IDENTIFICATION NUMBER LIABILITY COMPANY OR TRUST BY: /s/ Xxxxxxx X. Xxxxxxxxx DELAWARE NEW YORK ------------------------- ------------------------------ NAME: XXXXXXX X. XXXXXXXXX STATE OF ORGANIZATION TITLE: 000 XXXXXXX XXXXXX, JULY 18MAY 27, 2005 XXX XXXX, XX 00000 ---------------------------- ------------------------------ DATE ADDRESS VYTERIS HOLDINGS (NEVADA), INC. By: /s/ Xxxxxxx XxXxxxxxxx XxXxxxxx --------------------------- Name: Xxxxxxx XxXxxxxxxx XxXxxxxx, Ph.D. Title: Vice President and Chief Financial Executive Officer ACCREDITED INVESTOR CERTIFICATION Initial the appropriate item(s) THE UNDERSIGNED FURTHER REPRESENTS AND WARRANTS AS INDICATED BELOW BY THE UNDERSIGNED'S INITIALS:

Omnibus Signature Page. This Subscription Agreement is intended to be read and construed in conjunction with the Warrant Agreement, the Security Agreement, the Note and the Warrant. Accordingly, pursuant to the terms and conditions of this Subscription Agreement and such related agreements it is hereby agreed that the execution by the Lender of this Subscription Agreement, in the place set forth herein, shall constitute agreement to be bound by the terms and conditions hereof and the terms and conditions of the Warrant Agreement and the Security Agreement (as amended pursuant to Section 6 of this Subscription Agreement), with the same effect as if each of such separate but related agreement were separately signed. VYTERIS HOLDINGS (NEVADA), INC. OMNIBUS SIGNATURE PAGE TO SUBSCRIPTION AGREEMENT, WARRANT AGREEMENT AND SECURITY AGREEMENT Date (NOTE: To be completed by subscriber): July 18May 27, 2005 -------------------------------------------------------------------------------- If the Purchaser is an INDIVIDUAL, and if purchased as JOINT TENANTS, as TENANTS IN COMMON, or as COMMUNITY PROPERTY: ---------------------------- ------------------------------ PRINT NAME(S) SOCIAL SECURITY NUMBER(S) --------------------------- ---------------------------- ------------------------------ SIGNATURE(S) OF SUBSCRIBER(S) SIGNATURE ---------------------------- ------------------------------ DATE ADDRESS If the Purchaser is a PARTNERSHIP, CORPORATION, LIMITED LIABILITY COMPANY or TRUST: XXXXXXX XXXXX SPECIALTY GROUPPRIVATE EQUITY FUND II, LLC ---------------------------- ------------------------------ NAME OF PARTNERSHIP, FEDERAL TAXPAYER CORPORATION, LIMITED IDENTIFICATION NUMBER LIABILITY COMPANY OR TRUST BY: /s/ Xxxxxxx X. Xxxxxxxxx DELAWARE NEW YORK ------------------------- ------------------------------ NAME: XXXXXXX X. XXXXXXXXX STATE OF ORGANIZATION TITLE: 000 XXXXXXX XXXXXX, JULY 18MAY 27, 2005 XXX XXXX, XX 00000 ---------------------------- ------------------------------ DATE ADDRESS VYTERIS HOLDINGS (NEVADA), INC. By: /s/ Xxxxxxx XxXxxxxxxx XxXxxxxx --------------------------- Name: Xxxxxxx XxXxxxxxxx XxXxxxxx, Ph.D. Title: Vice President and Chief Financial Executive Officer ACCREDITED INVESTOR CERTIFICATION Initial the appropriate item(s) THE UNDERSIGNED FURTHER REPRESENTS AND WARRANTS AS INDICATED BELOW BY THE UNDERSIGNED'S INITIALS:

Omnibus Signature Page. This Subscription Agreement is intended to be read and construed in conjunction with the Warrant Agreement, the Security Agreement, the Note and the Warrant. Accordingly, pursuant to the terms and conditions of this Subscription Agreement and such related agreements it is hereby agreed that the execution by the Lender of this Subscription Agreement, in the place set forth herein, shall constitute agreement to be bound by the terms and conditions hereof and the terms and conditions of the Warrant Agreement and the Security Agreement (as amended pursuant to Section 6 of this Subscription Agreement), with the same effect as if each of such separate but related agreement were separately signed. VYTERIS HOLDINGS (NEVADA), INC. OMNIBUS SIGNATURE PAGE TO SUBSCRIPTION AGREEMENT, WARRANT AGREEMENT AND SECURITY AGREEMENT Date (NOTE: To be completed by subscriber): July 18June 21, 2005 -------------------------------------------------------------------------------- If the Purchaser is an INDIVIDUAL, and if purchased as JOINT TENANTS, as TENANTS IN COMMON, or as COMMUNITY PROPERTY: ---------------------------- ------------------------------ PRINT NAME(S) SOCIAL SECURITY NUMBER(S) --------------------------- ------------------------------ SIGNATURE(S) OF SUBSCRIBER(S) SIGNATURE ---------------------------- ------------------------------ DATE ADDRESS If the Purchaser is a PARTNERSHIP, CORPORATION, LIMITED LIABILITY COMPANY or TRUST: XXXXXXX XXXXX SPECIALTY GROUP, LLC ---------------------------- ------------------------------ NAME OF PARTNERSHIP, FEDERAL TAXPAYER CORPORATION, LIMITED IDENTIFICATION NUMBER LIABILITY COMPANY OR TRUST BY: /s/ Xxxxxxx X. Xxxxxxxxx DELAWARE ------------------------- ------------------------------ NAME: XXXXXXX X. XXXXXXXXX STATE OF ORGANIZATION TITLE: 000 XXXXXXX XXXXXX, JULY 18JUNE 21, 2005 XXX XXXX, XX 00000 ---------------------------- ------------------------------ DATE ADDRESS VYTERIS HOLDINGS (NEVADA), INC. By: /s/ Xxxxxxx XxXxxxxxxx --------------------------- XxXxxxxx -------------------- Name: Xxxxxxx XxXxxxxxxx XxXxxxxx, Ph.D. Title: Vice President and Chief Financial Executive Officer ACCREDITED INVESTOR CERTIFICATION Initial the appropriate item(s) THE UNDERSIGNED FURTHER REPRESENTS AND WARRANTS AS INDICATED BELOW BY THE UNDERSIGNED'S INITIALS:

Omnibus Signature Page. This Subscription Agreement is intended to be read and construed in conjunction with the Warrant Agreement, Registration Rights Agreement pertaining to the Security Agreement, issuance by the Note Company of the shares of Common Stock and Warrants to subscribers pursuant to the WarrantMemorandum. Accordingly, pursuant to the terms and conditions of this Subscription Agreement and such related agreements it is hereby agreed that the execution by the Lender Purchaser of this Subscription Agreement, in the place set forth herein, shall constitute agreement to be bound by the terms and conditions hereof and the terms and conditions of the Warrant Agreement and the Security Agreement (as amended pursuant to Section 6 of this Subscription Registration Rights Agreement), with the same effect as if each of such separate but related agreement were separately signed. VYTERIS HOLDINGS (NEVADA)HYBRIDON, INC. OMNIBUS SIGNATURE PAGE TO SUBSCRIPTION AGREEMENT AND REGISTRATION RIGHTS AGREEMENT SUBSCRIBER HEREBY ELECTS TO SUBSCRIBE UNDER THE SUBSCRIPTION AGREEMENT FOR A TOTAL OF ____ UNITS AT A PRICE OF U.S. $250,000 PER UNIT (NOTE: TO BE COMPLETED BY SUBSCRIBER) AND EXECUTES THE SUBSCRIPTION AGREEMENT AND THE REGISTRATION RIGHTS AGREEMENT, WARRANT AGREEMENT AGREES TO BE BOUND BY THE TERMS AND SECURITY AGREEMENT CONDITIONS THEREOF AND AUTHORIZES THIS SIGNATURE PAGE TO BE ATTACHED THERETO. Date (NOTE: To be completed by subscriber): July 18August 28, 2005 -------------------------------------------------------------------------------- If the Purchaser is an INDIVIDUAL, and if purchased as 2003 IF THE PURCHASER IS AN INDIVIDUAL (IF PURCHASED AS JOINT TENANTS, as AS TENANTS IN COMMON, or as OR AS COMMUNITY PROPERTY: ---------------------------- ------------------------------ PRINT NAME(S, EACH OWNER MUST COMPLETE SEPARATE SIGNATURE PAGE): ____________________________ _____________________________________ Print Name Social Security Number (if applicable) SOCIAL SECURITY NUMBER(S) --------------------------- ------------------------------ SIGNATURE(S) OF SUBSCRIBER(S) SIGNATURE ---------------------------- ------------------------------ DATE ADDRESS If the Purchaser is a ____________________________ _____________________________________ Signature of Subscriber Signature ____________________________ _____________________________________ Date Address IF THE PURCHASER IS A PARTNERSHIP, CORPORATION, LIMITED LIABILITY COMPANY or OR TRUST: XXXXXXX XXXXX SPECIALTY GROUPOptima Life Sciences Limited ---------------------------- _____________________________________ Name of Partnership, LLC ---------------------------- ------------------------------ NAME OF PARTNERSHIPFederal Taxpayer Corporation, FEDERAL TAXPAYER CORPORATION, LIMITED IDENTIFICATION NUMBER LIABILITY COMPANY OR TRUST BYLimited Identification Number (if applicable) Liability Company or Trust By: /s/ Xxxxxxx X. Xxxxxxxxx DELAWARE ------------------------- Youssef El-Zein Isle of Man ------------------------------ NAME------------------------------------- Name: XXXXXXX X. XXXXXXXXX STATE OF ORGANIZATION TITLEYoussef El-Zein Jurisdiction of Organization Title: 000 XXXXXXX XXXXXXDirector Xx. Xxxxx'x Xxxxxxxx, JULY 1864A Athol St., 2005 XXX XXXXAugust 28, XX 00000 ---------------------------- ------------------------------ DATE ADDRESS VYTERIS HOLDINGS (NEVADA)2003 Xxxxxxx, Isle of Man IM1 1JE ---------------------------------- ------------------------------------- Date Address ACCEPTED: HYBRIDON, INC. By: /s/ Xxxxxxx XxXxxxxxxx --------------------------- Xxxxxx ------------------ Name: Xxxxxxx XxXxxxxxxx Xxxxxx Title: Vice President and Chief Financial Officer ACCREDITED INVESTOR CERTIFICATION Initial the appropriate item(s) THE UNDERSIGNED FURTHER REPRESENTS AND WARRANTS AS INDICATED BELOW BY THE UNDERSIGNED'S INITIALS:Executive Officer

Omnibus Signature Page. This Subscription Agreement is intended to be read and construed in conjunction with the Warrant Agreement, the Security Agreement, the Note and the Warrant. Accordingly, pursuant to the terms and conditions of this Subscription Agreement and such related agreements it is hereby agreed that the execution by the Lender of this Subscription Agreement, in the place set forth herein, shall constitute agreement to be bound by the terms and conditions hereof and the terms and conditions of the Warrant Agreement and the Security Agreement (as amended pursuant to Section 6 of this Subscription Agreement), with the same effect as if each of such separate but related agreement were separately signed. VYTERIS HOLDINGS (NEVADA), INC. OMNIBUS SIGNATURE PAGE TO SUBSCRIPTION AGREEMENT, WARRANT AGREEMENT AND SECURITY AGREEMENT Date (NOTE: To be completed by subscriber): July 1813, 2005 -------------------------------------------------------------------------------- If the Purchaser is an INDIVIDUAL, and if purchased as JOINT TENANTS, as TENANTS IN COMMON, or as COMMUNITY PROPERTY: ---------------------------- ------------------------------ PRINT NAME(S) SOCIAL SECURITY NUMBER(S) --------------------------- ------------------------------ SIGNATURE(S) OF SUBSCRIBER(S) SIGNATURE ---------------------------- ------------------------------ DATE ADDRESS If the Purchaser is a PARTNERSHIP, CORPORATION, LIMITED LIABILITY COMPANY or TRUST: XXXXXXX XXXXX SPECIALTY GROUP, LLC ---------------------------- ------------------------------ NAME OF PARTNERSHIP, FEDERAL TAXPAYER CORPORATION, LIMITED IDENTIFICATION NUMBER LIABILITY COMPANY OR TRUST BY: /s/ Xxxxxxx X. Xxxxxxxxx DELAWARE ------------------------- ------------------------------ NAME: XXXXXXX X. XXXXXXXXX STATE OF ORGANIZATION TITLE: 000 XXXXXXX XXXXXX, JULY 1813, 2005 XXX XXXX, XX 00000 ---------------------------- ------------------------------ DATE ADDRESS VYTERIS HOLDINGS (NEVADA), INC. By: /s/ Xxxxxxx XxXxxxxxxx --------------------------- Name: Xxxxxxx XxXxxxxxxx Title: Vice President and Chief Financial Officer ACCREDITED INVESTOR CERTIFICATION Initial the appropriate item(s) THE UNDERSIGNED FURTHER REPRESENTS AND WARRANTS AS INDICATED BELOW BY THE UNDERSIGNED'S INITIALS:

Omnibus Signature Page. This Subscription Agreement is intended to be read and construed in conjunction with the Warrant Agreement, the Security Agreement, the Note and the Warrant. Accordingly, pursuant to the terms and conditions of this Subscription Agreement and such related agreements it is hereby agreed that the execution by the Lender of this Subscription Agreement, in the place set forth herein, shall constitute agreement to be bound by the terms and conditions hereof and the terms and conditions of the Warrant Agreement and the Security Agreement (as amended pursuant to Section 6 of this Subscription Agreement), with the same effect as if each of such separate but related agreement were separately signed. VYTERIS HOLDINGS (NEVADA), INC. OMNIBUS SIGNATURE PAGE TO SUBSCRIPTION AGREEMENT, WARRANT AGREEMENT AND SECURITY AGREEMENT Date (NOTE: To be completed by subscriber): July 18June 2, 2005 -------------------------------------------------------------------------------- If the Purchaser is an INDIVIDUAL, and if purchased as JOINT TENANTS, as TENANTS IN COMMON, or as COMMUNITY PROPERTY: ---------------------------- ------------------------------ PRINT NAME(S) SOCIAL SECURITY NUMBER(S) --------------------------- ------------------------------ SIGNATURE(S) OF SUBSCRIBER(S) SIGNATURE ---------------------------- ------------------------------ DATE ADDRESS If the Purchaser is a PARTNERSHIP, CORPORATION, LIMITED LIABILITY COMPANY or TRUST: XXXXXXX XXXXX SPECIALTY GROUPPRIVATE EQUITY FUND II, LLC LP ---------------------------- ------------------------------ NAME OF PARTNERSHIP, FEDERAL TAXPAYER CORPORATION, LIMITED IDENTIFICATION NUMBER LIABILITY COMPANY OR TRUST BY: /s/ Xxxxxxx X. Xxxxxxxxx DELAWARE NEW YORK ------------------------- ------------------------------ NAME: XXXXXXX X. XXXXXXXXX STATE OF ORGANIZATION TITLE: 000 XXXXXXX XXXXXX, JULY 18JUNE 2, 2005 XXX XXXX, XX 00000 ---------------------------- ------------------------------ DATE ADDRESS VYTERIS HOLDINGS (NEVADA), INC. By: /s/ Xxxxxxx XxXxxxxxxx --------------------------- XxXxxxxx -------------------- Name: Xxxxxxx XxXxxxxxxx XxXxxxxx, Ph.D. Title: Vice President and Chief Financial Executive Officer ACCREDITED INVESTOR CERTIFICATION Initial the appropriate item(s) THE UNDERSIGNED FURTHER REPRESENTS AND WARRANTS AS INDICATED BELOW BY THE UNDERSIGNED'S INITIALS:

Omnibus Signature Page. This Subscription Agreement is intended to be read and construed in conjunction with the Warrant Agreement, the Security Agreement, the Note and the Warrant. Accordingly, pursuant to the terms and conditions of this Subscription Agreement and such related agreements it is hereby agreed that the execution by the Lender of this Subscription Agreement, in the place set forth herein, shall constitute agreement to be bound by the terms and conditions hereof and the terms and conditions of the Warrant Agreement and the Security Agreement (as amended pursuant to Section 6 of this Subscription Agreement), with the same effect as if each of such separate but related agreement were separately signed. VYTERIS HOLDINGS (NEVADA), INC. OMNIBUS SIGNATURE PAGE TO SUBSCRIPTION AGREEMENT, WARRANT AGREEMENT AND SECURITY AGREEMENT Date (NOTE: To be completed by subscriber): July 18June 2, 2005 -------------------------------------------------------------------------------- If the Purchaser is an INDIVIDUAL, and if purchased as JOINT TENANTS, as TENANTS IN COMMON, or as COMMUNITY PROPERTY: ---------------------------- ------------------------------ PRINT NAME(S) SOCIAL SECURITY NUMBER(S) --------------------------- ------------------------------ SIGNATURE(S) OF SUBSCRIBER(S) SIGNATURE ---------------------------- ------------------------------ DATE ADDRESS If the Purchaser is a PARTNERSHIP, CORPORATION, LIMITED LIABILITY COMPANY or TRUST: XXXXXXX XXXXX SPECIALTY GROUP, LLC ---------------------------- ------------------------------ NAME OF PARTNERSHIP, FEDERAL TAXPAYER CORPORATION, LIMITED IDENTIFICATION NUMBER LIABILITY COMPANY OR TRUST BY: /s/ Xxxxxxx X. Xxxxxxxxx DELAWARE NEW YORK ------------------------- ------------------------------ NAME: XXXXXXX X. XXXXXXXXX STATE OF ORGANIZATION TITLE: 000 XXXXXXX XXXXXX, JULY 18JUNE 2, 2005 XXX XXXX, XX 00000 ---------------------------- ------------------------------ DATE ADDRESS VYTERIS HOLDINGS (NEVADA), INC. By: /s/ Xxxxxxx XxXxxxxxxx XxXxxxxx --------------------------- Name: Xxxxxxx XxXxxxxxxx XxXxxxxx, Ph.D. Title: Vice President and Chief Financial Executive Officer ACCREDITED INVESTOR CERTIFICATION Initial the appropriate item(s) THE UNDERSIGNED FURTHER REPRESENTS AND WARRANTS AS INDICATED BELOW BY THE UNDERSIGNED'S INITIALS:

Omnibus Signature Page. This Subscription Agreement is intended to be read and construed in conjunction with the Warrant Agreement, the Security Agreement, the Note and the Warrant. Accordingly, pursuant to the terms and conditions of this Subscription Agreement and such related agreements it is hereby agreed that the execution by the Lender of this Subscription Agreement, in the place set forth herein, shall constitute agreement to be bound by the terms and conditions hereof and the terms and conditions of the Warrant Agreement and the Security Agreement (as amended pursuant to Section 6 of this Subscription Agreement), with the same effect as if each of such separate but related agreement were separately signed. VYTERIS HOLDINGS (NEVADA), INC. OMNIBUS SIGNATURE PAGE TO SUBSCRIPTION AGREEMENT, WARRANT AGREEMENT AND SECURITY AGREEMENT Date (NOTE: To be completed by subscriber): July 18June 2, 2005 -------------------------------------------------------------------------------- If the Purchaser is an INDIVIDUAL, and if purchased as JOINT TENANTS, as TENANTS IN COMMON, or as COMMUNITY PROPERTY: ---------------------------- ------------------------------ PRINT NAME(S) SOCIAL SECURITY NUMBER(S) --------------------------- ------------------------------ SIGNATURE(S) OF SUBSCRIBER(S) SIGNATURE ---------------------------- ------------------------------ DATE ADDRESS If the Purchaser is a PARTNERSHIP, CORPORATION, LIMITED LIABILITY COMPANY or TRUST: XXXXXXX XXXXX SPECIALTY GROUP, ILLUMINATION FUND LLC ---------------------------- ------------------------------ NAME OF PARTNERSHIP, FEDERAL TAXPAYER CORPORATION, LIMITED IDENTIFICATION NUMBER LIABILITY COMPANY OR TRUST BY: /s/ Xxxxxxx X. Xxxxxxxxx DELAWARE NEW YORK ------------------------- ------------------------------ NAME: XXXXXXX X. XXXXXXXXX STATE OF ORGANIZATION TITLE: 000 XXXXXXX XXXXXX, JULY 18JUNE 2, 2005 XXX XXXX, XX 00000 ---------------------------- ------------------------------ DATE ADDRESS VYTERIS HOLDINGS (NEVADA), INC. By: /s/ Xxxxxxx XxXxxxxxxx --------------------------- XxXxxxxx -------------------- Name: Xxxxxxx XxXxxxxxxx XxXxxxxx, Ph.D. Title: Vice President and Chief Financial Executive Officer ACCREDITED INVESTOR CERTIFICATION Initial the appropriate item(s) THE UNDERSIGNED FURTHER REPRESENTS AND WARRANTS AS INDICATED BELOW BY THE UNDERSIGNED'S INITIALS:

Omnibus Signature Page. This Subscription Agreement is intended to be read and construed in conjunction with the Warrant Agreement, the Security Agreement, the Note and the Warrant. Accordingly, pursuant to the terms and conditions of this Subscription Agreement and such related agreements it is hereby agreed that the execution by the Lender of this Subscription Agreement, in the place set forth herein, shall constitute agreement to be bound by the terms and conditions hereof and the terms and conditions of the Warrant Agreement and the Security Agreement (as amended pursuant to Section 6 of this Subscription Agreement), with the same effect as if each of such separate but related agreement were separately signed. VYTERIS HOLDINGS (NEVADA), INC. OMNIBUS SIGNATURE PAGE TO SUBSCRIPTION AGREEMENT, WARRANT AGREEMENT AND SECURITY AGREEMENT Date (NOTE: To be completed by subscriber): July 18June 2, 2005 -------------------------------------------------------------------------------- If the Purchaser is an INDIVIDUAL, and if purchased as JOINT TENANTS, as TENANTS IN COMMON, or as COMMUNITY PROPERTY: ---------------------------- ------------------------------ PRINT NAME(S) SOCIAL SECURITY NUMBER(S) --------------------------- ------------------------------ SIGNATURE(S) OF SUBSCRIBER(S) SIGNATURE ---------------------------- ------------------------------ DATE ADDRESS If the Purchaser is a PARTNERSHIP, CORPORATION, LIMITED LIABILITY COMPANY or TRUST: XXXXXXX XXXXX SPECIALTY GROUPPRIVATE EQUITY FUND I, LLC LP ---------------------------- ------------------------------ NAME OF PARTNERSHIP, FEDERAL TAXPAYER CORPORATION, LIMITED IDENTIFICATION NUMBER LIABILITY COMPANY OR TRUST BY: /s/ Xxxxxxx X. Xxxxxxxxx DELAWARE NEW YORK ------------------------- ------------------------------ NAME: XXXXXXX X. XXXXXXXXX STATE OF ORGANIZATION TITLE: 000 XXXXXXX XXXXXX, JULY 18JUNE 2, 2005 XXX XXXX, XX 00000 ---------------------------- ------------------------------ DATE ADDRESS VYTERIS HOLDINGS (NEVADA), INC. By: /s/ Xxxxxxx XxXxxxxxxx --------------------------- XxXxxxxx -------------------- Name: Xxxxxxx XxXxxxxxxx XxXxxxxx Title: Vice President and Chief Financial Executive Officer ACCREDITED INVESTOR CERTIFICATION Initial the appropriate item(s) THE UNDERSIGNED FURTHER REPRESENTS AND WARRANTS AS INDICATED BELOW BY THE UNDERSIGNED'S INITIALS: