Dose & Route of administration ALWAYS PRESCRIBE ORAL DOSE USING 2 Sample Clauses

Dose & Route of administration ALWAYS PRESCRIBE ORAL DOSE USING 2. 5mg TABLETS Orally or subcutaneously (CRH hospital only- parenteral routes may be used where the patient fails to respond to or is intolerant of oral administration) Licensed indications Rheumatoid arthritis - 7.5mg – 25mg orally or subcutaneous injection ONCE WEEKLY Severe psoriasis unresponsive to conventional therapy. Initially 2.5mg-10mg once weekly. Then increased in steps of 2.5mg-5mg, adjusted according to response, dose to be adjusted at intervals of at least one week; usual dose 7.5-15mg once weekly. Maximum 30mg per week Unlicensed indications Crohn’s Disease - maintenance of remission of severe Crohn’s disease 10 – 25mg orally ONCE WEEKLY Psoriatic arthritis 7.5mg – 25mg orally or subcutaneous injection ONCE WEEKLY For other indication see BNF or as per specialist advice Doses outside the recommended range may be considered with prior agreement with the specialist team and GP involved. Lower doses should be considered for frail elderly and patients with renal impairment. Folic Acid 5mg at least once weekly should be prescribed whilst patient remains on Methotrexate.
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