Boulder Uses in Employment Clause

Employment from Employment Agreement

THIS EMPLOYMENT AGREEMENT (this "Agreement"), effective as of March 18, 2013 (the "Effective Date"), is between Array BioPharma Inc., a Delaware corporation (the "Company"), and Michael Needle, M.D. ("Employee").

Employment. The Company hereby employs Employee and Employee hereby agrees to be employed by the Company for the period and upon the terms and conditions hereinafter set forth. Employee shall commence full-time services on April 1, 2013 (such date is hereinafter referred to as the "Start Date"). The duties to be performed by Employee hereunder may be performed in Morristown, New Jersey or Boulder, Colorado, subject to reasonable travel requirements on behalf of the Company, or such other place as the Company may reasonably designate. Employee acknowledges that the Company's executive offices are located in Boulder, Colorado, where regular presence will be required, and that the Company also maintains other offices in the Boulder, Colorado and Raleigh, North Carolina areas, and that Employee will be required to travel frequently to such other offices of the Company.

Employment

This letter is to confirm our understanding with respect to your employment with OSI Pharmaceuticals, Inc., its subsidiaries or affiliates (the Company).

Employment. The Company will initially employ you, and you agree to be employed by the Company as Vice President, Global Regulatory Affairs reporting to Nicole Onetto. The principal location at which you shall perform such services shall be the Companys facility located in Boulder, Colorado. Your employment hereunder shall commence on or about January 1, 2002 (the Commencement Date) and shall continue on an at-will" basis, meaning that either you or the Company may terminate your employment at any time and for any reason.