Antibody-Drug Conjugate means an Antibody that is linked to a cytotoxic compound and that contains, uses, is made using or is otherwise based on SGI Technology.
Antibody-Drug Conjugate or “ADC” shall mean an Antibody which has undergone a EuCODE Modification and/or a ReCODE Modification conjugated to Payload Technology.
Antibody-Drug Conjugate means an antibody conjugated to a cytotoxic payload.
Examples of Antibody-Drug Conjugate in a sentence
This agreement expands the application of Innate’s science beyond our oncology focus and demonstrates how our antibody engineering expertise can play a major role in developing Antibody Drug Conjugate formats.
More Definitions of Antibody-Drug Conjugate
Antibody-Drug Conjugate means [**].
Antibody-Drug Conjugate or “ADC” shall mean an Antibody which 1) has undergone modification through the incorporation, substitution or addition of one or more non-naturally encoded amino acids (i.e., amino acids other than the 20 naturally-encoded amino acids), 2) provides one or more specific site(s) in the amino acid sequence of the Antibody suitable for conjugation, and 3) is suitable and capable of being conjugated, linked or attached to one or more cytotoxic payload(s) via one or more specific site(s). For clarity, ADC includes an Antibody that has been conjugated, linked or attached to one or more cytotoxic payload(s) via one or more specific site(s).
Antibody-Drug Conjugate means an Antibody that is linked to a cytotoxin or cytostatic compound and that contains, uses or is made using Drug Conjugation Technology.
Antibody-Drug Conjugate or “ADC” means an antibody drug conjugate comprising an antibody (or fragment thereof) that is Directed To a Target and is conjugated to [ * ].
Antibody-Drug Conjugate means an Antibody [***] or [***] and that contains, uses or is made using Drug Conjugation Technology. Confidential treatment has been requested for portions of this exhibit. The copy filed herewith omits the information subject to the confidentiality request. Omissions are designated as ***. A complete version of this exhibit has been filed separately with the Securities and Exchange Commission.
Antibody-Drug Conjugate means an antibody that is linked to a cytotoxin or cytostatic agent (generally, “cytotoxins”) and that contains, uses or is made using SGI Technology. “ADC Product Candidate” means each ADC comprising an Antibody targeted to a Designated Antigen to which Agensys has a Research License under Section 10.1.1 and which has not yet been designated as a Collaboration Product or Unilateral Product hereunder. “ADC Research Program” means the research conducted pursuant to Article 3. “ADC Research Program Term” means the term of the ADC Research Program set forth in Section 3.2. “Adverse Event” means any unfavorable and unintended medical occurrence in a human patient or subject who is administered a Product, including any undesirable sign (including abnormal laboratory findings of clinical concern), symptom or disease temporally associated with the use of such Product, whether or not considered related to such Product. “Affiliate” of a Party means any corporation or other business entity that, directly or indirectly, through one or more intermediaries, controls, is controlled by, or is under common control with a Party. As used in this definition of Affiliate, the term “control” means the direct or indirect ownership of [ * ] or more of the stock having the right to vote for directors thereof or the ability to otherwise control the management thereof. “Agensys ADC Know-How” means all Program Inventions developed by Agensys using SGI Technology, and that are necessary or useful for identifying, developing, making, using or selling ADC Product Candidates, Agensys Products or Agensys Licensed Products that specifically bind to any Designated Antigen or Exclusive Antigen. “Agensys ADC Patents” means all patent applications and patents that are Controlled by Agensys that claim Agensys ADC Know- How and/or ADC Product Candidates (to the extent SGI consents to the filing of such patent applications with respect to ADC Product Candidates in accordance with Section 10.1). -2-
Antibody-Drug Conjugate or “ADC” means an Antibody that (a) specifically binds to and that is directly or indirectly conjugated, linked, or otherwise modified to incorporate one or more cytotoxic agents (including protein degraders and proteosome inhibitors), corticosteroids, or small molecule immunomodulators (but specifically excluding cytokines), and (b) is designed to directly or indirectly cause the death or directly inhibit growth of an The term Antibody Drug Conjugate specifically excludes (i) NKCEs and (ii) the use of the Licensed Antibodies as naked Antibodies as a therapeutic.