Second Amendment to Lease (May 5th, 2016)

THIS SECOND AMENDMENT TO LEASE (the "Second Amendment") is made and entered into as of the Effective Date hereof, by and between 6800 BROKEN SOUND LLC, a Florida limited liability company and its successors or assigns ("Landlord"), and THERAPEUTICSMD, INC., a Nevada corporation authorized to do business in Florida ("Tenant").

Employment Agreement (December 22nd, 2015)

EMPLOYMENT AGREEMENT (this "Agreement"), by and between TherapeuticsMD, Inc., a Nevada corporation (the "Company"), and Brian Bernick, M.D. ("Executive") is entered into and effective as of the 17th day of December, 2015 (the "Effective Date").

Contract (November 27th, 2012)

Promissory Note Individual Long-term Debt, Type [Axis] February 24 Debt Issuance Financing [Axis] Promissory Note Entity VitaMed Promissory Note Number of Shares Under Company Option Award Type [Axis] Weighted Average Exercise Price Weighted Average Remaining Contractual Life in Years Aggregated Intrinstic Value Number of Shares Under Company Warrant Weighted Average Exercise Price Weighted Average Remaining Contractual Life in Years Aggregate Intrinstic Value June 19 Debt Issuance First United Line of Credit December 2011 Debt Issuance February 24 and June 19 combined Debt Issuance Warrants Issued in March 2012