Working Cell Bank definition

Working Cell Bank means a vialed collection of serially subcultivated cells generated by or on behalf of Trubion that is derived from the *** and/or the ***, as the context requires. The Working Cell Bank is used to establish seed cultures of the related Cell Line to initiate the Manufacturing Process.
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Working Cell Bank means a culture of cells derived from the Master Cell Bank and intended for use in the preparation of cell cultures used for production of Virus Seeds and/or Vaccines.
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Working Cell Bank means MEDIMMUNE's vialed collection serially subcultivated cells that is derived from the Master Cell Bank. The Working Cell Bank is used to establish seed cultures of the Cell Line to initiate the Process.
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Examples of Working Cell Bank in a sentence

  • Cell Bank Maintenance and Record Keeping General remark:It is usual to maintain a Master Cell Bank (MCB) and a Working Cell Bank.

  • A general statement on the establishment of the Master Cell Bank (MCB) or Working Cell Bank (WCB) and on the stability of the cell banks is also not considered commercially confidential.

  • The Working Cell Bank (WCB) was established without the use of materials from human or animal origin.

  • An explanation of the batch numbering system, including information regarding any pooling of harvests or intermediates and batch size or scale should be provided.• A flow diagram should be provided that illustrates the manufacturing route from the original inoculum (e.g., cells contained in one or more vials(s) of the Working Cell Bank up to the last harvesting operation.

  • The Working Cell Bank (WCB) is derived from the MCB, following expansion by serial subculture to a specified passage number (refer to “Points to Consider in the Characterization of Cell Lines Used to Produce Biologicals” dated May 1993)5.


More Definitions of Working Cell Bank

Working Cell Bank or “WCB” means a vialed collection of serially sub-cultivated cells expressing the Licensed Compound that is derived from the Master Cell Bank under GMP conditions, and used to establish seed cultures for the Manufacturing of drug substance.
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Working Cell Bank means the following microogranisms: [***].
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Working Cell Bank means the cell bank as set out in Appendix 6 from which the API is manufactured.
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Working Cell Bank means the cell bank from which the API is manufactured. [***] Indicates that information has been omitted and filed separately with the Securities and Exchange Commission. Confidential treatment has been requested with respect to the omitted portions.
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Working Cell Bank or “WCB” means the vialled collection of cells derived from the MCB, created beginning in Stage 6 on Schedule 2 hereto or a similar applicable Stage on an applicable Future Schedule;
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Working Cell Bank or "WCB" means the clonal cell line that has been designed and engineered to produce DX-2930, and shall be supplied to Xxxxxxxxxx by Dyax.
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Working Cell Bank or “WCB” and “Master Cell Bank” or “MCB” means the clonal cell line that has been designed and engineered to produce a recombinant protein which is further defined in a Work Order. A WCB or MCB can either be supplied to Xxxxxxxxxx by Dyax or be prepared by Xxxxxxxxxx as further defined in a Work Order.
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