Tractable definition

Tractable including variations such as “Tractability” means that a target derived peptide is detectable by mass-spectrometry at levels supportive of achieving biological activity using an ImmTAC and the expression profile of the target by qRT-PCR suggests that a viable therapeutic window may be achievable.
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Tractable means solvable in practice, not polynomial-time computable as in computational complexity theory.‌
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Examples of Tractable in a sentence

  • For each of the second and third Selected Targets (but not with respect to the first Selected Target), GSK shall make a non-refundable, non-creditable milestone payment to EPIZYME of Two Million Dollars ($2,000,000) upon the achievement of Target Validation with respect to such Selected Target and GSK shall make a non-refundable, non-creditable milestone payment to EPIZYME of Two Million Dollars ($2,000,000) upon the identification of a Tractable Hit with respect to such Selected Target.

  • Tractable analysis can be done for a fixed UE with a small number of interfering base stations with the UE placed, for example, at the cell corner to simulate a worst case scenario and finding the SINR as in [59] [60].

  • Upon the JSC’s determination that any Compound satisfies the applicable Tractable Hit Criteria, such Compound shall be deemed a Tractable Hit for all purposes hereunder.

  • Upon the later to occur of (i) the Completion of Screening for [*] ([*]) Mitotic Kinesin Targets or (ii) [*] days after the end of Contract Year [*] (the "Lead Target Selection Date"), the JRC will reasonably determine the number of Mitotic Kinesin Targets, other than [*], for which at least one Tractable Compound has been identified (a "Lead Target"); provided, however, if [*] establishes a [*] Program with respect to a particular Mitotic Kinesin Target, such Target shall be deemed a Lead Target.

  • On a Selected Target-by-Selected Target basis, the JPT shall make a recommendation as to whether or not a Compound satisfies the applicable Tractable Hit Criteria, for review and approval by the JSC.

  • If Pharmacopeia succeeds in attaining a Tractable Hit under a Screening Program for an Initial Target during the first one (1) year period from the commencement by Pharmacopeia of actual screening of its compound library against such Initial Target (or such extended time period as may be determined and agreed in writing by the JSC), then, subject to Article 9 and Section 3.3.1, **.

  • Under the Science of Autonomy effort, JPL will support TEES by proposing "Tractable models for planning under uncertainty: Exploiting the power of belief resets".

  • During the relevant Screening Program, Pharmacopeia will conduct activities as described in the Work Plan for the relevant Program with the objective being to identify Tractable Hits and develop Leads from such Tractable Hits.

  • In addition, with respect to any Discontinued Program, Sections 3.3, 3.4 and 3.5 and any remaining obligations of exclusivity thereunder shall apply with respect to GSK only until the date which is two (2) years after the date of attainment of the Tractable Hit Criteria for such Target, as such Tractable Hit Criteria attainment dates are listed in Exhibit A, which is attached hereto and is hereby incorporated by reference.

  • The Parties shall agree in writing, on or before the Effective Date, upon the Tractable Hit Criteria, Lead Declaration Criteria and provisional Candidate Selection Criteria applicable for the **.

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