PD-1 definition

PD-1 means programmed cell death protein 1.
PD-1 means programmed cell death protein 1, encoded by the PDCD1 gene, also known as CD279.
PD-1 means Programmed Death-1 receptor, also identified as CD279, and encoded by the PDCD1 gene.

Examples of PD-1 in a sentence

  • It is not necessary to put them by name (S1, ...., Sn, or PD1, ...

  • Mor, Affinity purification mass spectrometry analysis of PD-1 uncovers SAP as a new checkpoint inhibitor, Proc.

  • In November 2019, SELLAS announced that follow-up data from its Phase 1 clinical trial of GPS in combination with nivolumab to treat Wilms Tumor 1 (WT1) positive patients with ovarian cancer in second- or third-line remission continues to support the development of GPS in combination with PD-1 inhibitors.

  • In April 2019, SELLAS announced an agreement with Memorial Sloan Kettering Cancer Center (MSK) for the conduct of an investigator-sponsored clinical trial (IST) of GPS in combination with Bristol-Myers Squibb’s anti- PD-1 therapy, nivolumab, in patients with malignant pleural mesothelioma (MPM).

  • Carlomagno, Molecular mechanism of SHP2 activation by PD-1 stimulation, Sci.

  • Note: Use ofmonoclonal antibodies (mAbs) before administration ofstudy vaccine and during the study conduct is permitted with the exception ofthose targeting Tcells (anti- CD3, CD4, CD33, and CD52), B cells (anti-CD45, CD19, CD20, CD22, CD27, CD38,and CD138) and check point inhibitors (PD-1, PDL-1 and CTLA-4).

  • Notwithstanding any other provision of this Agreement, if the terms of a BNT PD-1 License prevent OncoC4 from co-funding the Development of a Mono/PD-1 Combination under an amended CDP, and because of such BNT PD-1 License such Development is not conducted under the CDP, the Parties shall discuss in good faith appropriate amendments to Section 7.4(a) so that OncoC4 is not prevented from earning an equitable portion of any Development Milestone Payment(s) as a result of such BNT PD-1 License.

  • Combination blockade of KLRG1 and PD-1 promotes immune control of local and disseminated cancers.

  • OncoC4 and BioNTech shall use Commercially Reasonable Efforts to conduct Development activities with respect to the Licensed Compound and Licensed Products, either as a monotherapy or in combination solely with a PD-1 Product (collectively, the “Mono/PD-1 Combinations”), in each case, in accordance with a joint clinical development plan (the “CDP”) approved by the JSC in accordance with the terms of this Agreement.


More Definitions of PD-1

PD-1 means the cell surface receptor protein commonly referred to as “Programmed Cell Death Protein 1” or “PD-1.” *** CERTAIN INFORMATION IN THIS DOCUMENT HAS BEEN OMITTED AND FILED SEPARATELY WITH THE SECURITIES AND EXCHANGE COMMISSION. CONFIDENTIAL TREATMENT HAS BEEN REQUESTED WITH RESPECT TO THE OMITTED PORTIONS. CONFIDENTIAL TREATMENT REQUESTED
PD-1 means programmed death-1, and refers to an inhibitory checkpoint receptor expressed on T cells, which binds with PD-L1 and PD-L2 to inhibit T cell and cytokine activation.
PD-1 means the Target programmed death-1 protein[***].
PD-1 the City approval for a 269 unit multifamily residential apartment complex approved by the City in Ord. 201, which is attached to that certain Notice dated January 17, 2014, recorded under Clerk’s File No. 20140022596 of the Hxxxxx County Real Property Records with various renderings and plans attached thereto.
PD-1 means the protein encoded by the human PD-1 gene, identified by the following UniProt number: Q15116.

Related to PD-1

  • Antibody means a molecule or a gene encoding such a molecule comprising or containing one or more immunoglobulin variable domains or parts of such domains or any existing or future fragments, variants, modifications or derivatives thereof.

  • Phase III Clinical Trial means a human clinical trial, the principal purpose of which is to demonstrate clinically and statistically the efficacy and safety of a Licensed Product for one or more indications in order to obtain Marketing Approval of such Licensed Product for such indication(s), as further defined in 21 C.F.R. §312.21 or a similar clinical study in a country other than the United States.

  • Phase I Clinical Trial means a clinical trial conducted in healthy humans or patients, which clinical trial is designed to establish the safety, drug-drug interactions and/or pharmacokinetics of an investigational drug given its intended use, and to support continued testing of such drug in Phase II Clinical Trials.

  • Phase II Clinical Trial means a controlled human clinical study that would satisfy the requirements of 21 CFR 312.21(b), conducted to study the effectiveness and establish the dose range of a Product for a particular Indication in patients with the disease or condition under study, including a Phase IIA Clinical Study or Phase IIB Clinical Study.

  • HIV means human immunodeficiency virus.